Neurocristic cutaneous hamartoma: A distinctive dermal melanocytosis with an unknown malignant potential

Modern Pathology

Volumn 11, Issue 6, 1998, Pages 573-578

  Mezebish, David ^a   Smith, Kathleen ^a   Williams, John ^a   Menon, Padman ^a   Crittenden, Jacob ^a   Skelton, Henry ^b  

^a WALTER REED ARMY MEDICAL CENTER   (United States)

^b LABORATORY CORPORATION OF AMERICA   (United States)

Author keywords

Hair follicles; Melanocytic; Neuromesenchyme; Schwann

Indexed keywords

EPITHELIAL MEMBRANE ANTIGEN;

ADULT; ARTICLE; CASE REPORT; DYSPLASIA; FEMALE; HAIR FOLLICLE; HAMARTOMA; HUMAN; IMMUNOHISTOCHEMISTRY; MALIGNANT TRANSFORMATION; MELANOCYTE; MELANOCYTOSIS; MESENCHYME CELL; METASTASIS POTENTIAL; PRIORITY JOURNAL; SCHWANN CELL; SKIN FIBROBLAST; SPINDLE CELL;

ADULT; ANTIGENS, NEOPLASM; CA-15-3 ANTIGEN; FEMALE; HAMARTOMA; HUMANS; IMMUNOENZYME TECHNIQUES; MELANOCYTES; NEOPLASM PROTEINS; NEURAL CREST; S100 PROTEINS; SKIN DISEASES;

EID: 0031842797     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Reed RJ. Neuromesenchyme: the concept of a neurocristic effector cell for dermal mesenchyme. Am J Dermatopathol 1983;4:385-95.
2. Pearson JP, Weiss SW, Headington JT. Cutaneous malignant melanotic neurocristic tumors arising in neurocristic hamartomas. Am J Surg Pathol 1996;20:665-77.
3. Nakamura H. Mesenchymal derivatives from the neural crest. Arch Histol Jpn 1982;45:127-38.
4. Pathy AL, Helm TN, Elson D, Bergfeld WF, Tuthill RJ. Malignant melanoma arising in a blue nevus with features of pilar neurocristic hamartoma. J Cutan Pathol 1993;20:459-64.
5. Tuthill RJ, Clark WH, Levene A. Pilar neurocristic hamartoma: its relationship to blue nevus and equine melanotic disease. Arch Dermatol 1982;118:592-6.
6. Pittman JL, Fisher BK. Plaque-type blue nevus. Arch Dermatol 1976;112:1127-8.
7. Levene A. Disseminated dermal melanocytosis terminating in melanoma: a human condition resembling equine melanotic disease. Br J Dermatol 1979;101:197-205.
8. Mevorah B, Frenk E, Delacretas J. Dermal melanocytosis: report of an unusual case. Dermatologica 1977;154:107-14.
9. Le Douarin NM. Migration and differentiation of neural crest cells. Curr Top Dev Biol 1980;16:31-85.
10. Le Douarin NM, Cell line segregation during peripheral nervous lineages in the neural crest. Glia 1991;4:175-84.
11. Wachtler F. On the differentiation and migration of some non-neuronal neural crest-derived cell types. Anat Embryol (Berl) 1984;170:161-8.
12. Rutledge JC. Research advances in prenatal craniofacial development: report of a conference and review of topics. Pediatr Pathol 1989;9:613-21.
13. Skelton HG, Smith KJ, Barrett TL, Lupton GP, Graham JH. HMB45 in benign and malignant melanocytic lesions. Am J Dermatopathol 1991;13:543-50.
14. Mark GJ, Mihm MC, Litelpo MG, Reed RI, Clark WH. Congenital melanocytic nevi of the small and garment type: clinical, histologic, and ultrastructural studies. Hum Pathol 1973;4:395-418.
15. Cramer SF. The melanocytic differentiation pathway in congenital melanocytic nevi: theoretical considerations. Pediatr Pathol 1988;8:253-65.
16. Weiss SW, Nickoloff BJ. CD34 is expressed by a distinctive cell population in peripheral nerve, nerve sheath tumors, and related lesions. Am J Surg Pathol 1993;17:1039-45.
17. Reed R, von Boxberg Y, Lofberg J. Local embryonic matrices determine region-specific phenotypes in neural crest cells. Science 1988;241:86-9.
18. Hendrickson MR, Ross JC. Neoplasms arising in congenital giant nevi: morphologic study of seven cases and a review of the literature. Am J Surg Pathol 1981;5:109-35.
19. Connelly J, Smith JL Jr. Malignant blue nevus. Cancer 1991; 67:2653-7.
20. Elder DE, Murphy GF. In: Melanocytic tumors of the skin. Atlas of tumor pathology. 3rd series. Fasc 2. Washington, DC: Armed Forces Institute of Pathology; 1991. p. 64-78.