메뉴 건너뛰기




Volumn 18, Issue 13, 2007, Pages 1319-1322

Homocysteine is toxic for dopaminergic neurons in primary mesencephalic culture

Author keywords

1 methyl 4 phenylpyridinium; Dopamine; Tyrosine hydroxylase

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; HOMOCYSTEINE; MICROTUBULE PROTEIN; TYROSINE 3 MONOOXYGENASE;

EID: 34548319411     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/WNR.0b013e3282aaa0b4     Document Type: Article
Times cited : (36)

References (23)
  • 2
    • 0345600889 scopus 로고    scopus 로고
    • Hyperhomocysteinemia as an independent risk factor for silent brain infarction
    • Kim NK, Choi BO, Jung WS, Choi YJ, Choi KG. Hyperhomocysteinemia as an independent risk factor for silent brain infarction. Neurology 2003; 61:1595-1599.
    • (2003) Neurology , vol.61 , pp. 1595-1599
    • Kim, N.K.1    Choi, B.O.2    Jung, W.S.3    Choi, Y.J.4    Choi, K.G.5
  • 3
    • 0038387939 scopus 로고    scopus 로고
    • Homocysteine and Alzheimer's disease
    • Morris MS. Homocysteine and Alzheimer's disease. Lancet Neurol 2003; 2:425-428.
    • (2003) Lancet Neurol , vol.2 , pp. 425-428
    • Morris, M.S.1
  • 4
    • 0037289759 scopus 로고    scopus 로고
    • Homocysteine-evoked 45Ca release in the rabbit hippocampus is mediated by both NMDA and group I metabotropic glutamate receptors: In vivo microdialysis study
    • Lazarewicz JW, Ziembowicz A, Matyja E, Stafiej A, Zieminska E. Homocysteine-evoked 45Ca release in the rabbit hippocampus is mediated by both NMDA and group I metabotropic glutamate receptors: in vivo microdialysis study. Neurochem Res 2003; 28:259-269.
    • (2003) Neurochem Res , vol.28 , pp. 259-269
    • Lazarewicz, J.W.1    Ziembowicz, A.2    Matyja, E.3    Stafiej, A.4    Zieminska, E.5
  • 5
    • 0030915272 scopus 로고    scopus 로고
    • Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor
    • Lipton SA, Kim WK, Choi YB, Kumar S, D'Emilia DM, Rayudu PV, et al. Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor. Proc Natl Acad Sci USA 1997; 94:5923-5928.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 5923-5928
    • Lipton, S.A.1    Kim, W.K.2    Choi, Y.B.3    Kumar, S.4    D'Emilia, D.M.5    Rayudu, P.V.6
  • 6
    • 0018096158 scopus 로고
    • Methionine requirement and replacement by homocysteine in tissue cultures of selected rodent and human malignant and normal cells
    • Kreis W, Goodenow M. Methionine requirement and replacement by homocysteine in tissue cultures of selected rodent and human malignant and normal cells. Cancer Res 1978; 38:2259-2262.
    • (1978) Cancer Res , vol.38 , pp. 2259-2262
    • Kreis, W.1    Goodenow, M.2
  • 7
    • 0028849482 scopus 로고
    • Metabolism of homocysteine, its relation to the other cellular thiols and its mechanism of cell damage in a cell culture line (human histiocytic cell line U-937)
    • Hultberg B, Andersson A, Isaksson A. Metabolism of homocysteine, its relation to the other cellular thiols and its mechanism of cell damage in a cell culture line (human histiocytic cell line U-937). Biochim Biophys Acta 1995; 1269:6-12.
    • (1995) Biochim Biophys Acta , vol.1269 , pp. 6-12
    • Hultberg, B.1    Andersson, A.2    Isaksson, A.3
  • 9
    • 0031613978 scopus 로고    scopus 로고
    • Thermolabile methylenetetrahydrofolate reductase polymorphism (C677T) and total homocysteine concentration among African-American and white women
    • Giles WH, Kittner SJ, Ou CY, Croft JB, Brown V, Buchholz DW, et al. Thermolabile methylenetetrahydrofolate reductase polymorphism (C677T) and total homocysteine concentration among African-American and white women. Ethn Dis 1998; 8:149-157.
    • (1998) Ethn Dis , vol.8 , pp. 149-157
    • Giles, W.H.1    Kittner, S.J.2    Ou, C.Y.3    Croft, J.B.4    Brown, V.5    Buchholz, D.W.6
  • 10
    • 0037426415 scopus 로고    scopus 로고
    • Effect of L-dopa on plasma homocysteine in PD patients: Relationship to B-vitamin status
    • Miller JW, Selhub J, Nadeau MR, Thomas CA, Feldman RG, Wolf PA. Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status. Neurology 2003; 60:1125-1129.
    • (2003) Neurology , vol.60 , pp. 1125-1129
    • Miller, J.W.1    Selhub, J.2    Nadeau, M.R.3    Thomas, C.A.4    Feldman, R.G.5    Wolf, P.A.6
  • 12
    • 0036270262 scopus 로고    scopus 로고
    • Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease
    • Duan W, Ladenheim B, Cutler RG, Kruman II, Cadet JL, Mattson MP. Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease. J Neurochem 2002; 80:101-110.
    • (2002) J Neurochem , vol.80 , pp. 101-110
    • Duan, W.1    Ladenheim, B.2    Cutler, R.G.3    Kruman, I.I.4    Cadet, J.L.5    Mattson, M.P.6
  • 13
    • 20344396838 scopus 로고    scopus 로고
    • Effects of homocysteine on the dopaminergic system and behavior in rodents
    • Lee ES, Chen H, Soliman KF, Charlton CG. Effects of homocysteine on the dopaminergic system and behavior in rodents. Neurotoxicology 2005; 26:361-371.
    • (2005) Neurotoxicology , vol.26 , pp. 361-371
    • Lee, E.S.1    Chen, H.2    Soliman, K.F.3    Charlton, C.G.4
  • 14
    • 33644903828 scopus 로고    scopus 로고
    • Acute intranigral homocysteine administration produces stereotypic behavioral changes and striatal dopamine depletion in Sprague-Dawley rats
    • Chandra G, Gangopadhyay PK, Senthil Kumar KS, Mohanakumar KP. Acute intranigral homocysteine administration produces stereotypic behavioral changes and striatal dopamine depletion in Sprague-Dawley rats. Brain Res 2006; 1075:81-92.
    • (2006) Brain Res , vol.1075 , pp. 81-92
    • Chandra, G.1    Gangopadhyay, P.K.2    Senthil Kumar, K.S.3    Mohanakumar, K.P.4
  • 16
    • 0034624968 scopus 로고    scopus 로고
    • Kashiwaya Y, Takeshima T, Mori N, Nakashima K, Clarke K, Veech RL. D-beta-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease. Proc Natl Acad Sci USA 2000; 97:5440-5444.
    • Kashiwaya Y, Takeshima T, Mori N, Nakashima K, Clarke K, Veech RL. D-beta-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease. Proc Natl Acad Sci USA 2000; 97:5440-5444.
  • 17
    • 0028834192 scopus 로고
    • L-dopa cytotoxicity to PC12 cells in culture is via its autoxidation
    • Basma AN, Morris EJ, Nicklas WJ, Geller HM. L-dopa cytotoxicity to PC12 cells in culture is via its autoxidation. J Neurochem 1995; 64:825-832.
    • (1995) J Neurochem , vol.64 , pp. 825-832
    • Basma, A.N.1    Morris, E.J.2    Nicklas, W.J.3    Geller, H.M.4
  • 18
    • 0031240873 scopus 로고    scopus 로고
    • Vesicular neurotransmitter transporters. Potential sites for the regulation of synaptic function
    • Varoqui H, Erickson JD. Vesicular neurotransmitter transporters. Potential sites for the regulation of synaptic function. Mol Neurobiol 1997; 15:165-191.
    • (1997) Mol Neurobiol , vol.15 , pp. 165-191
    • Varoqui, H.1    Erickson, J.D.2
  • 19
    • 0026684489 scopus 로고
    • Synaptosomal plasma membrane transport of excitatory sulphur amino acid transmitter candidates: Kinetic characterisation and analysis of carrier specificity
    • Grieve A, Butcher SP, Griffiths R. Synaptosomal plasma membrane transport of excitatory sulphur amino acid transmitter candidates: kinetic characterisation and analysis of carrier specificity. J Neurosci Res 1992; 32:60-68.
    • (1992) J Neurosci Res , vol.32 , pp. 60-68
    • Grieve, A.1    Butcher, S.P.2    Griffiths, R.3
  • 20
    • 0029751103 scopus 로고    scopus 로고
    • The etiology of Parkinson's disease with emphasis on the MPTP story
    • Langston JW. The etiology of Parkinson's disease with emphasis on the MPTP story. Neurology 1996; 47(6 Suppl 3):S153-S160.
    • (1996) Neurology , vol.47 , Issue.6 SUPPL. 3
    • Langston, J.W.1
  • 22
    • 0034813210 scopus 로고    scopus 로고
    • Folate deficiency-induced oxidative stress and apoptosis are mediated via homocysteine-dependent overproduction of hydrogen peroxide and enhanced activation of NF-kappaB in human Hep G2 cells
    • Chern CL, Huang RF, Chen YH, Cheng JT, Liu TZ. Folate deficiency-induced oxidative stress and apoptosis are mediated via homocysteine-dependent overproduction of hydrogen peroxide and enhanced activation of NF-kappaB in human Hep G2 cells. Biomed Pharmacother 2001; 55:434-442.
    • (2001) Biomed Pharmacother , vol.55 , pp. 434-442
    • Chern, C.L.1    Huang, R.F.2    Chen, Y.H.3    Cheng, J.T.4    Liu, T.Z.5
  • 23
    • 33746543557 scopus 로고    scopus 로고
    • Mitochondrial mechanism of microvascular endothelial cells apoptosis in hyperhomocysteinemia
    • Tyagi N, Ovechkin AV, Lominadze D, Moshal KS, Tyagi SC. Mitochondrial mechanism of microvascular endothelial cells apoptosis in hyperhomocysteinemia. J Cell Biochem 2006; 98:1150-1162.
    • (2006) J Cell Biochem , vol.98 , pp. 1150-1162
    • Tyagi, N.1    Ovechkin, A.V.2    Lominadze, D.3    Moshal, K.S.4    Tyagi, S.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.