Outcome of Henoch-Schönlein purpura nephritis treated with long-term immunosuppression

Pediatric Nephrology

Volumn 22, Issue 10, 2007, Pages 1717-1722

  Shenoy, Mohan ^a   Bradbury, Mark G ^a   Lewis, Malcolm A ^a   Webb, Nicholas J A ^a  

^a ROYAL MANCHESTER CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

Azathioprine; Cyclophosphamide; Henoch Sch nlein nephritis; Prognosis

Indexed keywords

AZATHIOPRINE; CREATININE; CYCLOPHOSPHAMIDE; METHYLPREDNISOLONE; PREDNISOLONE; PROTEIN; STEROID;

ADOLESCENT; ANAPHYLACTOID PURPURA; ANTIHYPERTENSIVE THERAPY; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL PROTOCOL; CONTROLLED STUDY; CONVALESCENCE; DRUG DOSE REDUCTION; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY BIOPSY; KIDNEY FAILURE; LONG TERM CARE; MALE; NEPHRITIS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN URINE LEVEL; PROTEINURIA; RETROSPECTIVE STUDY; TREATMENT DURATION;

ADOLESCENT; ADRENAL CORTEX HORMONES; AGE OF ONSET; AZATHIOPRINE; CHILD; CYCLOPHOSPHAMIDE; FEMALE; FOLLOW-UP STUDIES; GLOMERULAR FILTRATION RATE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; IMMUNOTHERAPY; MALE; NEPHRITIS; PROTEINURIA; PURPURA, SCHOENLEIN-HENOCH; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 34548317563     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-007-0557-4     Document Type: Article

References (27)

1. Coppo R, Amore A (2004) Henoch-Schönlein purpura. In: Avner ED, Harmon WE, Niaudet P (eds) Textbook of pediatric nephrology, 5th edn. Lippincottt Williams & Wilkins, pp 851-863
2. Narchi H (2005) Risk of long-term renal impairment and duration of follow-up recommended for Henoch-Schönlein purpura with normal or minimal urinary findings: A systematic review. Arch Dis Child 90:916-920
3. Meadow SR, Glasgow EF, White RHR, Moncrief MW, Cameron JS, Ogg CS (1972) Schönlein-Henoch nephritis. Q J Med 41:241-258
4. Koskimies O, Mir S, Rapola J, Vilska J (1981) Henoch-Schonlein nephritis: Long-term prognosis of unselected patients. Arch Dis Child 56:482-484
5. Counahan R, Winterborn MH, White RH, Heaton JM, Meadow SR, Bluett NH, Swetschin H, Cameron JS, Chantler C (1977) Prognosis of Henoch-Schonlein nephritis in children. BMJ 2:11-14
6. Stewart M, Savage JM, Bell B, McCord B (1988) Long-term renal prognosis of Henoch-Schonlein purpura in an unselected childhood population. Eur J Pediatr 147:113-115
7. Coppo R, Mazzucco G, Cagnoli L, Lupo A, Schena FP (1997) Long-term prognosis of Henoch-Schonlein nephritis in adults and children. Italian Group of Renal Immunopathology Collaborative Study on Henoch-Schonlein Purpura. Nephrol Dial Transplant 12:2277-2283
8. NAPRTCS annual report (2005) Available at https://web.emmes.com/study/ ped/annlrept/annlrept2005.pdf
9. UK Renal Registry Report (2005) UK Renal Registry, Bristol UK
10. Ronkainen J, Ala-Houhala M, Huttunen N-P, Jahnukainen T, Koskimies O, Ormala T, Nuutinen M (2003) Outcome of Henoch-Schönlein nephritis with nephrotic-range proteinuria. Clin Nephrol 60:80-84
11. Niaudet P, Habib R (1998) Methylprednisolone pulse therapy in the treatment of severe forms of Schönlein-Henoch nephritis. Pediatr Nephrol 12:238-243
12. Bunchman TE, Mauer SM, Sibley RK, Vernier RL (1988) Anaphylactoid purpura: Characteristics of 16 patients who progressed to renal failure. Pediatr Nephrol 2:393-397
13. Goldstein AR, White RHR, Akuse R, Chantler C (1992) Long-term follow-up of childhood Henoch-Schönlein nephritis. Lancet 339:280-282
14. Bergstein J, Leiser J, Andreoli SP (1998) Response of crescentic HSP nephritis to corticosteroid and azathioprine therapy. Clin Nephrol 49:9-14
15. Ronkainen J, Autio-Harmainen H, Nuutinen M (2003) Cyclosporin A for the treatment of severe Henoch-Schönlein glomerulonephritis. Pediatr Nephrol 18:1138-1142
16. Flynn JT, Smoyer WE, Bunchman TE, Kershaw DB, Sedman AB (2001) Treatment of Henoch-Schönlein purpura glomerulonephritis in children with high-dose corticosteroids plus oral cyclophosphamide. Am J Nephrol 21:128-133
17. Hattori M, Ito K, Konomoto T, Kawaguchi H, Yoshioka T, Khono M (1999) Plasmapheresis as the sole therapy for rapidly progressive Henoch-Schönlein purpura nephritis in children. Am J Kidney Dis 33:427-433
18. Shenoy M, Ognjanovic M, Coulthard MG (2007) Treating severe Henoch-Schonlein and IgA nephritis with plasmapheresis alone. Pediatr Nephrol 122:1167-1171
19. Tarshish P, Bernstein J, Edelmann CM (2004) Henoch-Schönlein purpura nephritis: Course of disease and efficacy of cyclophosphamide. Pediatr Nephrol 19:51-56
20. Schwartz GJ, Haycock GB, Edelman CM, Spitzer A (1976) A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics 51:875-878
21. Andreoli SP, Bergstein JM (1989) Treatment of severe IgA nephropathy in children. Pediatr Nephrol 3:248-253
22. Pillebout E, Thervet E, Hill G, Alberti C, Vanhille P, Nochy D (2002) Henoch-Schonlein purpura in adults: Outcome and prognostic factors. J Am Soc Nephrol 13:1271-1278
23. Kaku Y, Nohara K, Honda S (1998) Renal involvement in Henoch-Schonlein purpura: A multivariate analysis of prognostic factors. Kidney Int 53:1755-1759
24. Durkan A, Hodson EM, Willis NS, Craig JC (2005) Non-corticosteroid treatment for nephrotic syndrome in children. Cochrane Database Syst Rev Apr 18(2):CD002290
25. Kawasaki Y, Suzuki J, Suzuki H (2004) Efficacy of methylprednisolone and urokinase pulse therapy combined with or without cyclophosphamide in severe Henoch-Schonlein nephritis: A clinical and histopathological study. Nephrol Dial Transplant 19:858-864
26. Foster BJ, Bernard C, Drummond KN, Sharma AK (2000) Effective therapy for severe Henoch-Schonlein purpura nephritis with prednisolone and azathioprine: A clinical and histopathologic study. J Pediatr 136:370-375
27. Ronkainen J, Nuutinen M, Koskimies O (2002) The adult kidney 24years after childhood Henoch-Schönlein purpura. A retrospective cohort study. Lancet 360:666-670