Antiadenoviral effect of the α5β1 integrin receptor ligand, GRGDSP peptide, in serotypes that cause acute keratoconjunctivitis

Ophthalmologica

Volumn 221, Issue 5, 2007, Pages 326-330

  Uchio, Eiichi ^a   Kimura, Ryoji ^a   Huang, Yuh Huey ^a   Fuchigami, Aya ^a   Kadonosono, Kazuaki ^b   Hayashi, Akio ^c   Ishiko, Hiroaki ^c   Aoki, Koki ^d   Ohno, Shigeaki ^d  

^a FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b YOKOHAMA CITY UNIVERSITY MEDICAL CENTER   (Japan)

^c Mitsubishi Kagaku Bio Clinical Laboratories Inc   (Japan)

^d HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

5 1 integrin receptor ligand; Adenovirus; Conjunctivitis; GRGDSP peptide

Indexed keywords

GLYCYLARGINYLGLYCYLASPARTYLSERYLPROLINE; LIGAND; LYMPHOCYTE ANTIGEN RECEPTOR; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5; VERY LATE ACTIVATION ANTIGEN 5 RECEPTOR;

ACUTE DISEASE; ADENOVIRUS; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; KERATOCONJUNCTIVITIS; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROTYPE;

ACUTE DISEASE; ADENOVIRIDAE; ADENOVIRIDAE INFECTIONS; ANTIVIRAL AGENTS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTEGRIN ALPHA5BETA1; KERATOCONJUNCTIVITIS; LIGANDS; OLIGOPEPTIDES; SEROTYPING; VIRUS REPLICATION;

EID: 34548317314     PISSN: 00303755     EISSN: None     Source Type: Journal    
DOI: 10.1159/000104763     Document Type: Article

References (29)

1. Stehle T, Dermody TS: Structural similarities in the cellular receptors used by adenovirus and reovirus. Viral Immunol 2004;17:129-143.
2. Bewley MC, Springer K, Zhang YB, Freimuth P, Flanagan JM: Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR. Science 1999;286:1579-1583.
3. Arnberg N, Edlund K, Kidd AH, Wadell G: Adenovirus type 37 uses sialic acid as a cellular receptor. J Virol 2000;74:42-48.
4. Huang S, Kamata T, Takada Y, Ruggeri ZM, Nemerow GR: Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells. J Virol 1996;70: 4502-4508.
5. Nemerow GR, Cheresh DA, Wickham TJ: Adenovirus entry into host cells: a role for alpha(v) integrins. Trends Cell Biol 1994;4:52-55.
6. Wickham TJ, Mathias P, Cheresh DA, Nemerow GR: Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell 1993;73:309-319.
7. Davison E, Diaz RM, Hart IR, Santis G, Marshall JF: Integrin alpha5beta1-mediated adenovirus infection is enhanced by the integrin-activating antibody TS2/16. J Virol 1997;71:6204-6207.
8. Li E, Brown SL, Stupack DG, Puente XS, Cheresh DA, Nemerow GR: Integrin alpha(v)beta1 is an adenovirus coreceptor. J Virol 2001;75:5405-5409.
9. Meier O, Greber UF: Adenovirus endocytosis. J Gene Med 2003;5:451-462.
10. Freimuth P: A human cell line selected for resistance to adenovirus infection has reduced levels of the virus receptor. J Virol 1996;70:4081-4085.
11. Lagrota MH, Ciribelli-Guimaraes J, Pereira NA, Wigg MD, Fonseca ME: Antiviral chemotherapy: in vitro activity of ribavirin on DNA and RNA viruses. Rev Latinoam Microbiol 1982;24:121-124.
12. Lennette DA, Eiferman RA: Inhibition of adenovirus replication in vitro by trifluridine. Arch Ophthalmol 1978;96:1662-1663.
13. Gordon YJ, Romanowski E, Araullo-Cruz T, Seaberg L, Erzurum S, Tolman R, De Clercq E: Inhibitory effect of (S)-HPMPC, (S)-HPMPA, and 2′-nor-cyclic GMP on clinical ocular adenoviral isolates is serotype-dependent in vitro. Antiviral Res 1991;16:11-16.
14. Murphy GF, Wood DP, McRoberts JW, Henslee-Downey PJ: Adenovirus- associated hemorrhagic cystitis treated with intravenous ribavirin. J Urol 1993;149:565-566.
15. Fanourgiakis P, Georgala A, Vekemans M, Triffet A, De Bruyn JM, Duchateau V, Martiat P, De Clercq E, Snoeck R, Wollants E, Rector A, Van Ranst M, Aoun M: Intravesical instillation of cidofovir in the treatment of hemorrhagic cystitis caused by adenovirus type 11 in a bone marrow transplant recipient. Clin Infect Dis 2005;40:199-201.
16. Kaneko H, Kato K, Mori S, Shigeta S: Antiviral activity of NMSO3 against adenovirus in vitro. Antiviral Res 2001;52:281-288.
17. v integrins. J Virol 2000;74:7691-7693.
18. Wickham TJ, Carrion ME, Kovesdi I: Targeting of adenovirus penton base to new receptors through replacement of its RGD motif with other receptor-specific peptide motifs. Gene Ther 1995;2:750-756.
19. Katagiri YU, Sleeman J, Fujii H, Herrlich P, Hotta H, Tanaka K, Chikuma S, Yagita H, Okumura K, Murakami M, Saiki I, Chambers AF, Uede T: CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis. Cancer Res 1999;59:219-226.
20. Tanaka-Yokogui K, Itoh N, Usui N, Takeuchi S, Uchio E, Aoki K, Usui M, Ohno S: New genome type of adenovirus serotype 19 causing nosocomial infections of epidemic keratoconjunctivitis in Japan. J Med Virol 2001;65:530-533.
21. Wadell G, de Jong JC: Restriction endonucleases in identification of a genome type of adenovirus 19 associated with keratoconjunctivitis. Infect Immun 1980;27:292-296.
22. Green M, Pina M: Biochemical studies on adenovirus multiplication. 6. Properties of highly purified tumorigenic human adenoviruses and their DNA. Proc Natl Acad Sci USA 1964;51:1251-1259.
23. Kowalczynska HM, Nowak-Wyrzykowska M, Kolos R, Dobkowski J, Kaminski J: Fibronectin adsorption and arrangement on copolymer surfaces and their significance in cell adhesion. J Biomed Mater Res A 2005;72:228-236.
24. Oharazawa H, Ibaraki N, Ohara K, Reddy VN: Inhibitory effects of Arg-Gly-Asp (RGD) peptide on cell attachment and migration in a human lens epithelial cell line. Ophthalmic Res 2005;37:191-196.
25. Durmort C, Stehlin C, Schoehn G, Mitraki A, Drouet E, Cusack S, Burmeister WP: Structure of the fiber head of Ad3, a non-CAR-binding serotype of adenovirus. Virology 2001;285:302-312.
26. Shayakhmetov DM, Eberly AM, Li ZY, Lieber A: Deletion of penton RGD motifs affects the efficiency of both the internalization and the endosome escape of viral particles containing adenovirus serotype 5 or 35 fiber knobs. J Virol 2005;79:1053-1061.
27. Burmeister WP, Guilligay D, Cusack S, Wadell G, Arnberg N: Crystal structure of species D adenovirus fiber knobs and their sialic acid binding sites. J Virol 2004;78:7727-7736.
28. Mei YF, Lindman K, Wadell G: Human adenoviruses of subgenera B, C, and E with various tropisms differ in both binding to and replication in the epithelial A549 and 293 cells. Virology 2002;295:30-43.
29. Mei YF, Segerman A, Lindman K, Hornsten P, Wahlin A, Wadell G: Human hematopoietic (CD34+) stem cells possess high-affinity receptors for adenovirus type 11p. Virology 2004;328:198-207.