Cardiovascular responses to somatosensory stimulation and their modulation by baroreflex mechanisms

Clinical and Experimental Hypertension

Volumn 29, Issue 6, 2007, Pages 403-418

  Kawabe, Tetsuya ^a   Kawabe, Kazumi ^a   Sapru, Hreday N ^a  

^a New Jersey Medical School   (United States)

Author keywords

Aortic nerve; Barodenervation; NTS; RVLM; Sciatic nerve; Somatosensory stimulation

Indexed keywords

EXCITATORY AMINO ACID; GLUTAMIC ACID; URETHAN;

AMINO ACID TRANSPORT; ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA NERVE; ARTICLE; ARTIFICIAL VENTILATION; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; MALE; MICROINJECTION; NEUROMODULATION; NOCICEPTIVE STIMULATION; NONHUMAN; PRESSORECEPTOR REFLEX; RAT; SCIATIC NERVE; SOLITARY TRACT NUCLEUS; SOMATOSENSORY CORTEX; SOMATOSENSORY STIMULATION;

AFFERENT PATHWAYS; ANIMALS; BAROREFLEX; BLOOD PRESSURE; CARDIOVASCULAR PHYSIOLOGY; CARDIOVASCULAR SYSTEM; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; HEART RATE; MALE; MEDULLA OBLONGATA; MICROINJECTIONS; RATS; RATS, WISTAR; REFLEX; SCIATIC NERVE; SOLITARY NUCLEUS; SYMPATHETIC NERVOUS SYSTEM;

EID: 34548316260     PISSN: 10641963     EISSN: 15256006     Source Type: Journal    
DOI: 10.1080/10641960701578402     Document Type: Article

References (33)

1. Boscan P, Paton JF. Role of the solitary tract nucleus in mediating nociceptive evoked cardiorespiratory responses. Auton Neurosci. 2001;86:170-182.
2. Boscan P, Pickering AE, Paton JF. The nucleus of the solitary tract: an integrating station for nociceptive and cardiorespiratory afferents. Exp Physiol. 2002;87:259-266.
3. Corbett EK, Batten TF, Kaye JC, Deuchars J, McWilliam PN. Labelling of rat vagal preganglionic neurons by carbocyanine dye DiI applied to the heart. Neuroreport. 1999;10:1177-1181.
4. Ermirio R, Ruggeri P, Molinari C, Weaver LC. Somatic and visceral inputs to neurons of the rostral ventrolateral medulla. Am J Physiol. 1993;265:R35-R40.
5. Esteves F, Lima D, Coimbra A. Structural types of spinal cord marginal (lamina I) neurons projecting to the nucleus of the tractus solitarius in the rat. Somatosens Mot Res. 1993;10:203-216.
6. Gamboa-Esteves FO, Tavares I, Almeida A, Batten TFC, McWilliam PN, Lima D. Projection sites of superficial and deep spinal dorsal horn cells in the nucleus tractus solitarii of the rat. Brain Res. 2001;921:195-205.
7. Gordon FJ. Excitatory amino acid receptors in central cardiovascular regulation. Clin Exp Hypertens. 1995;17:81-90.
8. Hallback M, Folkow B. Cardiovascular responses to acute mental "stress" in spontaneously hypertensive rats. Acta Physiol Scand. 1974;90:684-698.
9. Hirooka Y, Dampney RAL. Endogenous angiotensin within the rostral ventrolateral medulla facilitates the somatosympathetic reflex. J Hypertens. 1995;13:747-754.
10. Kawabe T, Chitravanshi VC, Kawabe K, Sapru HN. Cardiovascular effects of adrenocorticotropin microinjections into the rostral ventrolateral medullary pressor area of the rat. Brain Res. 2006;1102:117-126.
11. Kiely J, Gordon FJ. Non-NMDA receptors in the rostral ventrolateral medulla mediate somatosympathetic pressor responses. J Auton Nerv Syst. 1993;43:231-240.
12. Makeham JM, Goodchild AK, Pilowsky PM. NK1 receptor activation in rat rostral ventrolateral medulla selectively attenuates somato-sympathetic reflex while antagonism attenuates sympathetic chemoreflex. Am J Physiol. 2005;288:R1707-R1715.
13. McKitrick DJ, Calaresu FR. Expression of Fos in rat central nervous system elicited by afferent stimulation of the femoral nerve. Brain Res. 1993;632:127-135.
14. Menetrey D, Basbaum A. Spinal and trigeminal projections to the nucleus of the solitary tract: a possible substrate for somatovisceral and viscerovisceral reflex activation. J Comp Neurol. 1987;255:439-450.
15. Miyawaki T, Goodchild AK, Pilowsky PM. Activation of mu-opioid receptors in rat ventrolateral medulla selectively blocks baroreceptor reflexes while activation of delta opioid receptors blocks somato-sympathetic reflexes. Neuroscience 2002;109:133-144.
16. Morrison SF, Reis D. Reticulospinal vasomotor neurons in the RVL mediate the somatosympathetic reflex. Am J Physiol. 1989;256:R1084-R1097.
17. Nosaka S, Sato A, Shimada F. Somatosplanchnic reflex discharges in rats. J Auton Nerv Syst 1980;2:95-104.
18. th ed. New York: Academic Press, 1998.
19. Pezzone MA, Lee WS, Hoffman GE, Pezzone KM, Rabin BS. Activation of brainstem catecholaminergic neurons by conditioned and unconditioned aversive stimuli as revealed by c-Fos immunoreactivity. Brain Res. 1993;608:310-318.
20. Pickering AE, Boscan P, Paton JF. Nociception attenuates parasympathetic but not sympathetic baroreflex via NK1 receptors in the rat nucleus tractus solitarii. J Physiol. 2003;551:589-599.
21. Potts JT, Li J. Interaction between carotid baroreflex and exercise pressor reflex depends on baroreceptor afferent input. Am J Physiol. 1998;274:H1841-H1847.
22. Potts JT, Lee SM, Anguelov PI. Tracing of projection neurons from the cervical dorsal horn to the medulla with the anterograde tracer biotinylated dextran amine. Auton Neurosci. 2002;98:64-69.
23. Randich A, Maixner W. Interactions between cardiovascular and pain regulatory systems. Neurosci Biobehav Rev. 1984;8:343-367.
24. Sapru HN. Baroreceptor reflex components and their alteration in hypertension. In: Reflex control of the circulation, eds. Zucker IH and Gilmore JP. Boca Raton: CRC Press, 1991, pp. 195-214.
25. Sapru HN. Glutamate circuits in selected medullo-spinal areas regulating cardiovascular function. Clin Exp Pharmacol Physiol. 2002;29:491-496.
26. Sapru HN, Krieger AJ. Procedure for the decerebration of the rat. Brain Res Bull. 1978;3:675-679.
27. Sato A, Schmidt RF. Somatosympathetic reflexes: afferent fibers, central pathways, discharge characteristics. Physiol. 1973;Rev 53:916-947.
28. Scherrer U, Pryor SL, Bertocci LA, Victor RG. Arterial baroreflex buffering of sympathetic activation during exercise-induced elevations in arterial pressure. J Clin Invest. 1990;86:1855-1861.
29. Stornetta RL, Morrison SF, Ruggiero DA, Reis DJ. Neurons of rostral ventrolateral medulla mediate somatic pressor reflex. Am J Physiol. 1989;256:R448-R462.
30. Talman WT, Perrone MH, Reis DJ. Evidence for L-glutamate as neurotransmitter of baroreceptor afferent nerve fibers. Science. 1980;209:813-815.
31. Toney GM, Mifflin SW. Sensory modalities conveyed in the hindlimb somatic afferent input to nucleus tractus solitarius. J Appl Physiol. 2002;88:2062-2073.
32. Viard E, Sapru HN. Endomorphin-2 in the medial NTS attenuates the responses to baroreflex activation. Brain Res. 2006;1073-1074:365-373.
33. Zanzinger J, Czachurski J, Offner B, Seller H. Somato-sympathetic reflex transmission in the ventrolateral medulla oblongata: spatial organization and receptor types. Brain Res. 1994;656:353-358.