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For recent reviews on metal-catalyzed C-C bond coupling reactions, see: Metal-Catalyzed Cross-Coupling Reactions, Vol. 1-2, 2nd ed. (Eds.: A. de Meijere, F. Diederich), Wiley-VCH, Weinheim, 2006.
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For other pioneering studies, see refs. [10] and [11].
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37
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This system was used by Cahiez for the cross-coupling between vinyl bromides and alkyl Grignard reagents, see ref, 14c
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This system was used by Cahiez for the cross-coupling between vinyl bromides and alkyl Grignard reagents, see ref. [14c].
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1H NMR spectroscopy.
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1H NMR spectroscopy.
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Yield determined by NMR spectroscopy
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Yield determined by NMR spectroscopy.
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Other alkenyl Grignard reagents were also examined. When vinylmagnesium bromide was used, the major product observed was the elimination product from the starting alkyl halide. When styrylmagnesium bromide was used, incomplete conversion was observed, and the cross-coupling product was obtained along with both the elimination and reduction products
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Other alkenyl Grignard reagents were also examined. When vinylmagnesium bromide was used, the major product observed was the elimination product from the starting alkyl halide. When styrylmagnesium bromide was used, incomplete conversion was observed, and the cross-coupling product was obtained along with both the elimination and reduction products.
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For other iron-catalyzed 5-exo-trig cyclizations, see ref. [17d] and: D. Nečas, M. Kotora, I. Císařová, Eur. J. Org. Chem. 2004, 1280-1285.
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For other iron-catalyzed 5-exo-trig cyclizations, see ref. [17d] and: D. Nečas, M. Kotora, I. Císařová, Eur. J. Org. Chem. 2004, 1280-1285.
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