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Volumn 46, Issue 34, 2007, Pages 6521-6524

Iron-catalyzed cross-coupling of alkyl halides with alkenyl Grignard reagents

Author keywords

Alkyl halides; Grignard reagents; Homogeneous catalysis; Iron; Sustainable chemistry

Indexed keywords

CATALYSIS; CHEMICAL BONDS; COUPLING AGENTS; HALOGEN COMPOUNDS; REACTION RATES;

EID: 34548299141     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200702206     Document Type: Article
Times cited : (189)

References (42)
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  • 2
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    • For recent reviews on metal-catalyzed cross-coupling reactions with alkyl halides, see: a
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    • For other pioneering studies, see refs, 10] and [11
    • For other pioneering studies, see refs. [10] and [11].
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    • For other iron-catalyzed cross-coupling reactions of alkyl halides with aryl Grignard reagents, see: a
    • For other iron-catalyzed cross-coupling reactions of alkyl halides with aryl Grignard reagents, see: a) T. Nagano, T. Hayashi, Org. Lett. 2004, 6, 1297-1299;
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    • This system was used by Cahiez for the cross-coupling between vinyl bromides and alkyl Grignard reagents, see ref, 14c
    • This system was used by Cahiez for the cross-coupling between vinyl bromides and alkyl Grignard reagents, see ref. [14c].
  • 38
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    • 1H NMR spectroscopy.
    • 1H NMR spectroscopy.
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    • Yield determined by NMR spectroscopy
    • Yield determined by NMR spectroscopy.
  • 40
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    • Other alkenyl Grignard reagents were also examined. When vinylmagnesium bromide was used, the major product observed was the elimination product from the starting alkyl halide. When styrylmagnesium bromide was used, incomplete conversion was observed, and the cross-coupling product was obtained along with both the elimination and reduction products
    • Other alkenyl Grignard reagents were also examined. When vinylmagnesium bromide was used, the major product observed was the elimination product from the starting alkyl halide. When styrylmagnesium bromide was used, incomplete conversion was observed, and the cross-coupling product was obtained along with both the elimination and reduction products.
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    • For other iron-catalyzed 5-exo-trig cyclizations, see ref. [17d] and: D. Nečas, M. Kotora, I. Císařová, Eur. J. Org. Chem. 2004, 1280-1285.
    • For other iron-catalyzed 5-exo-trig cyclizations, see ref. [17d] and: D. Nečas, M. Kotora, I. Císařová, Eur. J. Org. Chem. 2004, 1280-1285.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.