Early dietary treatments with Lorenzo's oil and docosahexaenoic acid for neurological development in a case with Zellweger syndrome

Brain and Development

Volumn 29, Issue 9, 2007, Pages 586-589

  Tanaka, Kyoko ^a   Shimizu, Toshiaki ^a   Ohtsuka, Yoshikazu ^a   Yamashiro, Yuichiro ^a   Oshida, Kyoichi ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Docosahexaenoic acid; Lorenzo's oil; Lunaria oil; Zellweger syndrome

Indexed keywords

15 TETRACOSENOIC ACID; DOCOSAHEXAENOIC ACID; FATTY ACID DERIVATIVE; GLYCYRRHIZIC ACID; LORENZO OIL; LUNARIA OIL; TAURINE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ARTICLE; ARTIFICIAL MILK; CASE REPORT; CHOLESTASIS; DENVER DEVELOPMENTAL SCREENING TEST; DIET THERAPY; ERYTHROCYTE MEMBRANE; FATTY ACID ANALYSIS; FEMALE; HUMAN; LIVER DYSFUNCTION; NERVOUS SYSTEM DEVELOPMENT; NEUROLOGIC EXAMINATION; ZELLWEGER SYNDROME;

CHILD DEVELOPMENT; DOCOSAHEXAENOIC ACIDS; DRUG COMBINATIONS; DRUG THERAPY, COMBINATION; ERUCIC ACIDS; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; FATTY ACIDS; FEMALE; HUMANS; INFANT, NEWBORN; TREATMENT OUTCOME; TRIGLYCERIDES; TRIOLEIN; ZELLWEGER SYNDROME;

EID: 34548289424     PISSN: 03877604     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.braindev.2007.02.005     Document Type: Article

References (11)

1. Martinez M., Vaazazquez E., Garcia-Shilva M.T., Manzanares J., Bertran J.M., Castell F., et al. Therapeutic effects of docosahexaenoic acid ethylester in patients with generalized peroxisomal disorders. Am J Clin Nutr 71 (2000) 376S-385S
2. Martinez M. Docosahexaenoic acid therapy in docosahexaenoic acid-deficient patient with disorders of peroxisomal biogenesis. Lipids 31 (1996) S145-S152
3. Martinez M. Polyunsaturated fatty acids in the developing human brain, erythrocytes and plasma in peroxisomal disease: therapeutic implications. J Inherit Metab Dis 18 (1995) 61-75
4. Martinez M., Vazquez E., Garcia-Silva M.T., Beltran J.M., Castello F., Pineda M., et al. Treatment of generalized peroxisomal disorders with docosahexaenoic acid ethyl ether. Rev Neurol 28 (1999) S59-S64
5. Moser H.W., Loes D.J., Melhem E.R., Raymond G.V., Bezman L., and Cox C.S. X-linked adrenoleukodystrophy: overview and prognosis as a function of age and brain magnetic resonance imaging abnormality. A study involving 372 patients. Neuropediatrics 31 (2000) 227-239
6. Martinez M. Polyunsaturated fatty acid changes suggesting a new enzymatic defect in Zellweger syndrome. Lipids 24 (1989) 261-265
7. Cook C., Barnett J., Coupland K., and Sargent J. Effects of feeding Lunaria oil rich in nervonic and erucic acids on the fatty acid compositions of sphingomyelins from erythrocytes, liver, and brain of the quaking mouse mutant. Lipids 33 (1998) 993-1000
8. Martinez M., Mougan I., Roig M., and Ballabriga A. Blood polyunsaturated fatty acids in patients with peroxisomal disorders. A multicenter study. Lipids 29 (1994) 273-280
9. Ferdinandusse S., Denis S., Mooijer P.A., Zhang Z., Reddy J.K., Spector A.A., et al. Identification of the peroxisomal beta-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid. J Lipid Res 42 (2001) 1987-1995
10. Huyghe S., Casteels M., Janssen A., Meulders L., Mannaerts G.P., Declercq P.E., et al. Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse. Biochem J 353 (2001) 673-680
11. Suzuki Y., Shimozawa N., Imamura A., Fukuda Y., Ichihashi H., Orii T., et al. Trial of docosahexaenoic acid supplementation on a Japanese patient with a peroxisome biogenesis defect. Acta Paediatr Jpn 38 (1996) 520-523