Effect of extracts and isolated compounds from Chresta scapigera on viability of Leishmania amazonensis and Trypanosoma cruzi

Revista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences

Volumn 43, Issue 2, 2007, Pages 295-300

  Schinor, Elisandra Cristina ^a   Salvador, Marcos José ^a,b   Pral, Elisabeth Mieko Furusho ^a   Alfieri, Silvia Celina ^a   Albuquerque, Sérgio ^a   Dias, Diones Aparecida ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO DE PESQUISA E DESENVOLVIMENTO   (Brazil)

Author keywords

Chresta scapigera leishmanicidal activity; Chresta scapigera trypanocidal activity; Flavonoids; Triterpenes

Indexed keywords

11ALPHA 12ALPHA OXIDETARAXERYL ACETATE; AMPHOTERICIN B; APIGENIN; BETA AMYRIN; CHRESTA SCAPIGERA EXTRACT; CRYSOERIOL; KAEMPFEROL; LUPEOL; LUTEOLIN; PLANT EXTRACT; TILIROSIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ARTICLE; CHRESTA SCAPIGERA; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; FRACTIONATION; LEISHMANIA; MEDICINAL PLANT; MOUSE; NONHUMAN; TRYPANOSOMA CRUZI;

EID: 34548277032     PISSN: 15169332     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1516-93322007000200016     Document Type: Article

References (15)

1. BARATA, L.E.S.; SANTOS, L.S.; FERRI, P.H.; PHILLIPSON, J.D.; PAINE, A.; CROFT, S.L. Anti-leishmanial activity of neolignans from Virola species and synthetic analogues. Phytochemistry, v. 55, p. 589-595, 2000.
2. BASTOS, J.K.; ALBUQUERQUE, S.; SILVA, M.L.A. Evaluation of the trypanocidal activity of lignans isolated from leaves of Zanthoxylum naranjillo. Planta Med., v. 65, p. 541-544, 1999.
3. BERGER, I.; PASSREITER, C.M.; CACERE, A.; KUBELKA, W. Antiprotozoal activity of Neurolaena lobata. Phytother. Res., v. 15, p. 327-330, 2001.
4. BRENER, Z. Therapeutic activity on criterion of cure on mice experimentally infected with Trypanosoma cruzi. Rev. Inst. Med. Trop. Sao Paulo, v. 4, p. 389-396, 1962.
5. COURA, J.R.; DE CASTRO, S.L. A critical review on Chagas disease chemotherapy. Mem. Inst. Oswaldo Cruz, v. 97, p. 3-24, 2002.
6. FOURNET, A.; MUÑOZ, V.; ROBLOT, F.; HOCQUEMILLER, R.; CAVÉ, A.; GANTIER, J.C. Antiprotozoal activity of dehydrozaluzanin C, a sesquiterpene lactone isolated from Munnozia maronii (Asteraceae). Phytother. Res., v. 7, p. 111-115, 1993.
7. GRAEL, C.F.F.; VICHNEWSKI, W.; DE SOUZA, G.E.P.; LOPES, J.L.C.; ALBUQUERQUE, S.; CUNHA, R.W. A study of the trypanocidal and analgesic properties from Lychnophora granmongolense (Duarte) Semir & Leitão Filho. Phytother. Res., v. 14, p. 203-206, 2000.
8. MAFEZOLI, J.; VIEIRA, J.C.; FERNANDES, J.B.; DA SILVA, M.F.G.F.; ALBUQUERQUE, S. In vitro activity of Rutaceae species against the trypomastigote form of Trypanosoma cruzi. J. Ethnopharmacol., v. 73, p. 335-340, 2000.
9. MOSMANN, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Imm. Method, v. 65, p. 55-63, 1983.
10. MUELAS-SERRANO, S.; NOGAL, J.J.; MARTINEZ-DÍAZ, R.A.; ESCARIO, J.A.; MARTINEZ-FERNANDEZ, J.R.; GÓMEZ-BARRIO, A. In vitro screening of American plant extracts on Trypanosoma cruzi and Trichomonas vaginalis. J. Ethnopharmacol., v. 71, p. 101-107, 2000.
11. OKETCH-RABAH, H.A.; CHRISTENSEN, S.B.; FRYDENVANG, K.; DOSSAJI, S.F.; THEANDER, T.G.; CORNETT, C.; WATKINS, W.M.; KHARAZMI, A.; LEMMICH, E. Antiprotozoal properties of 16,17-dihydrobrachycalyxolide from Vernonia brachycalyx. Planta Med., v. 64, p. 559-562, 2001.
12. RIBEIRO, A.; VELOSO, D.P. Trypanocidal flavonoids from Trixis vauthieri. J. Nat. Prod., v. 60, p. 836-838.
13. ROBINSON, H. Generic and subtribal classification of American Vernonieae, Smithsonian contributions to Botany, number 89. Washington: Smithsonian Institution Press, 1999. p. 116.
14. SALVADOR, M.J.; FERREIRA, E.O.; PRAL, E.M.F.; ALFIERI, S.C.; ALBUQUERQUE, S.; ITO, I.Y.; DIAS, D.A. Bioactivity of crude extracts and some constituents of Blutaparon portulacoides (Amaranthaceae). Phytomedicine, v. 9, p. 566-571, 2002.
15. SAUVAIN, M.; POISSON, J.; KUNESCH, N.; GANTIER, J.C.; GAYRAL, P.; DEDET, J.P. Osilation of leishmanicidal triterpenes and lignans from Amazonian Liana Doliocarpus dentatus (Dilleniaceae). Phytother. Res., v. 10, p. 1-4, 1996.