Integrating regimen adherence assessment into clinical practice

Promoting Treatment Adherence: A Practical Handbook for Health Care Providers

Volumn , Issue , 2006, Pages 17-34

  Riekert, Kristin A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

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[No Author keywords available]

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EID: 34548257517     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.4135/9781452225975.n2     Document Type: Chapter

References (82)

1. Anis, A. H., Lynd, L. D., Wang, X. H., King, G., Spinelli, J. J., Fitzgerald, M., et al. (2001). Double trouble: Impact of inappropriate use of asthma medication on the use of health care resources. CMAJ: Canadian Medical Association Journal, 164, 625-631.
2. Blair, S. N., Haskell, W. L., Ho, P., Paffenbarger, R. S., Jr., Vranizan, K. M., Farquhar, J. W., et al. (1985). Assessment of habitual physical activity by a seven-day recall in a community survey and controlled experiments. American Journal of Epidemiology, 122, 794-804.
3. Block, G., Gillespie, C., Rosenbaum, E. H., & Jenson, C. (2000). A rapid food screener to assess fat and fruit and vegetable intake. American Journal of Preventive Medicine, 18, 284-288. doi:10.1016/S0749-3797(00)00119-7 http://dx.doi.org/10.1016/S0749-3797%2800%2900119-7
4. Bronstein, J. M., Santer, L., & Johnson, V. (2000). The use of Medicaid claims as a supplementary source of information on quality of asthma care. Journal for Healthcare Quality, 22, 13-18. doi:10.1111/j.1945-1474.2000.tb00160.x http://dx.doi.org/10.1111/j.1945-1474.2000.tb00160.x
5. Brownlee-Duffeck, M., Peterson, L., Simonds, J. F., Goldstein, D., Kilo, C., & Hoette, S. (1987). The role of health beliefs in the regimen adherence and metabolic control of adolescents and adults with diabetes mellitus. Journal of Consulting and Clinical Psychology, 55, 139-144. doi:10.1037/0022-006X.55.2.139 http://dx.doi.org/10.1037/0022-006X.55.2.139
6. Burton, S., & Blair, E. (1991). Task conditions, response formulation processes, and response accuracy for behavioral frequency questions in surveys. Public Opinion Quarterly, 33, 50-79. doi:10.1086/269241 http://dx.doi.org/10.1086/269241
7. Calfas, K. J., Zabinski, M. F., & Rupp, J. (2000). Practical nutrition assessment in primary care settings: A review. American Journal of Preventive Medicine, 18, 289-299. doi:10.1016/S0749-3797(00)00116-1 http://dx.doi.org/10.1016/S0749-3797%2800%2900116-1
8. Cleemput, I., Kesteloot, K., & DeGeest, S. (2002). A review of the literature on the economics of noncompliance. Room for methodological improvement. Health Policy, 59, 65-94. doi:10.1016/S0168-8510(01)00178-6 http://dx.doi.org/10.1016/S0168-8510%2801%2900178-6
9. Conway, J. M., Seale, J. L., Jacobs, D. R., Jr., Irwin, M. L., & Ainsworth, B. E. (2002). Comparison of energy expenditure estimates from doubly labeled water, a physical activity questionnaire, and physical activity records. American Journal of Clinical Nutrition, 75, 519-525.
10. Courneya, K. S., & McAuley, E. (1995). Cognitive mediators of the social influence-exercise adherence relationship: A test of the theory of planned behavior. Journal of Behavioral Medicine, 18, 499-515. doi:10.1007/BF01904776 http://dx.doi.org/10.1007/BF01904776
11. Davies, P. D. (2003). The role of DOTS in tuberculosis treatment and control. American Journal of Respiratory Medicine, 2, 203-209.
12. DiMatteo, M. R. (2004). Variations in patients' adherence to medical recommendations: A quantitative review of 50 years of research. Medical Care, 42, 200-209. doi:10.1097/01.mlr.0000114908.90348.f9 http://dx.doi.org/10.1097/01.mlr.0000114908.90348.f9
13. DiMatteo, M. R., Giordani, P. J., Lepper, H. S., & Croghan, T. W. (2002). Patient adherence and medical treatment outcomes: A meta-analysis. Medical Care, 40, 794-811. doi:10.1097/00005650-200209000-00009 http://dx.doi.org/10.1097/00005650-200209000-00009
14. Dishman, R. K., & Steinhardt, M. (1988). Reliability and concurrent validity for a 7-day recall of physical activity in college students. Medicine and Science in Sports and Exercise, 20, 14-25. doi:10.1249/00005768-198802000-00003 http://dx.doi.org/10.1249/00005768-198802000-00003
15. Dubbert, P. M., King, A., Rapp, S. R., Brief, D., Martin, J. E., & Lake, M. (1985). Riboflavin as a tracer of medication compliance. Journal of Behavioral Medicine, 8, 287-299. doi:10.1007/BF00870315 http://dx.doi.org/10.1007/BF00870315
16. Erickson, S. R., Coombs, J. H., Kirking, D. M., & Azimi, A. R. (2001). Compliance from self-reported versus pharmacy claims data with metered-dose inhalers. Annals of Pharmacotherapy, 35, 997-1003. doi:10.1345/aph.10379 http://dx.doi.org/10.1345/aph.10379
17. Fairley, C. K., Levy, R., Rayner, C. R., Allardice, K., Costello, K., Thomas, C., et al. (2003). Randomized trial of an adherence programme for clients with HIV. International Journal of STD & AIDS, 14, 805-809. doi:10.1258/095646203322556129 http://dx.doi.org/10.1258/095646203322556129
18. Finney, J. W., Hook, R. J., Friman, P. C., Rapoff, M. A., & Christophersen, E. R. (1993). The overestimation of adherence to pediatric medical regimens. Child Health Care, 22, 297-304. doi:10.1207/s15326888chc2204_5 http://dx.doi.org/10.1207/s15326888chc2204_5
19. Flynn, M. F., Lyman, R. D., & Prentice-Dunn, S. (1995). Protection motivation theory and adherence to medical treatment regimens for muscular dystrophy. Journal of Social and Clinical Psychology, 14, 61-75. doi:10.1521/jscp.1995.14.1.61 http://dx.doi.org/10.1521/jscp.1995.14.1.61
20. Fotheringham, M. J., & Sawyer, M. G. (1995). Adherence to recommended medical regimens in childhood and adolescence. Journal of Paediatrics and Child Health, 31, 72-78. doi:10.1111/j.1440-1754.1995.tb00750.x http://dx.doi.org/10.1111/j.1440-1754.1995.tb00750.x
21. Fullmer, S., Geiger, C. J., & Parent, C. R. (1991). Consumers' knowledge, understanding, and attitudes toward health claims on food labels. Journal of the American Dietetic Association, 91, 166-171.
22. Gao, X., & Nau, D. P. (2000). Congruence of three self-report measures of medication adherence among HIV patients. Annals of Pharmacotherapy, 34, 1117-1122. doi:10.1345/aph.19339 http://dx.doi.org/10.1345/aph.19339
23. George, C. F., Peveler, R. C., Heiliger, S., & Thompson, C. (2000). Compliance with tricyclic antidepressants: The value of four different methods of assessment. British Journal of Clinical Pharmacology, 50, 166-171. doi:10.1046/j.1365-2125.2000.00244.x http://dx.doi.org/10.1046/j.1365-2125.2000.00244.x
24. Haskell, W. L., & Kiernan, M. (2000). Methodologic issues in measuring physical activity and physical fitness when evaluating the role of dietary supplements for physically active people. American Journal of Clinical Nutrition, 72, 541S-550S.
25. Haynes, R. B., Montague, P., Oliver, T., McKibbon, K. A., Brouwers, M. C., & Kanani, R. (2000). Interventions for helping patients to follow prescriptions for medications. Cochrane Database of Systematic Review, CD000011.
26. Hepke, K. L., Martus, M. T., & Share, D. A. (2004). Costs and utilization associated with pharmaceutical adherence in a diabetic population. American Journal of Managed Care, 10, 144-151.
27. Hesselink, A. E., Penninx, B. W., Wijnhoven, H. A., Kriegsman, D. M., & van Eijk, J. T. (2001). Determinants of an incorrect inhalation technique in patients with asthma or COPD. Scandinavian Journal of Primary Health Care, 19, 255-260. doi:10.1080/02813430152706792 http://dx.doi.org/10.1080/02813430152706792
28. Hinkin, C. H., Hardy, D. J., Mason, K. I., Castellon, S. A., Durvasula, R. S., Lam, M. N., et al. (2004). Medication adherence in HIV-infected adults: Effect of patient age, cognitive status, and substance abuse. AIDS, 18(Suppl. 1), S19-S25. doi:10.1097/00002030-200401001-00004 http://dx.doi.org/10.1097/00002030-200401001-00004
29. Hulka, B. S., Cassel, J. C., Kupper, L. L., & Burdette, J. A. (1976). Communication, compliance, and concordance between physicians and patients with prescribed medications. American Journal of Public Health, 66, 847-853. doi:10.2105/AJPH.66.9.847 http://dx.doi.org/10.2105/AJPH.66.9.847
30. Jeste, S. D., Patterson, T. L., Palmer, B. W., Dolder, C. R., Goldman, S., & Jeste, D. V (2003). Cognitive predictors of medication adherence among middle-aged and older outpatients with schizophrenia. Schizophrenia Research, 63, 49-58. doi:10.1016/S0920-9964(02)00314-6 http://dx.doi.org/10.1016/S0920-9964%2802%2900314-6
31. Jobe, J. B. (2000). Cognitive processes in self-report. In A. A.Stone, J. S.Turkkan, C. A.Bachrach, J. B.Jobe, H. S.Kurtzman, & V. S.Cain (Eds.), The science of self-report: Implications for research and practice (pp. 25-28). Mahwah, NJ: Erlbaum.
32. Johnson, S. B., Freund, A., Silverstein, J., Hansen, C. A., & Malone, J. (1990). Adherence-health status relationships in childhood diabetes. Health Psychology, 9, 606-631. doi:10.1037/0278-6133.9.5.606 http://dx.doi.org/10.1037/0278-6133.9.5.606
33. Joshi, N., & Milfred, D. (1995). The use and misuse of new antibiotics. A perspective. Archives of Internal Medicine, 155, 569-577. doi:10.1001/archinte.1995.00430060026004 http://dx.doi.org/10.1001/archinte.1995.00430060026004
34. Krapek, K., King, K., Warren, S. S., George, K. G., Caputo, D. A., Mihelich, K., et al. (2004). Medication adherence and associated hemoglobin A1c in type 2 diabetes. Annals of Pharmacotherapy, 38, 1357-1362. doi:10.1345/aph.1D612 http://dx.doi.org/10.1345/aph.1D612
35. Kriska, A. M., & Caspersen, C. J. (1997). Introduction to a collection of physical activity questionnaires. Medicine and Science in Sports and Exercise, 29, S5-S9.
36. Lucas, G. M., Flexner, C. W., & Moore, R. D. (2002). Directly administered antiretroviral therapy in the treatment of HIV infection: Benefit or burden? AIDS Patient Care and STDs, 16, 527-535. doi:10.1089/108729102761041083 http://dx.doi.org/10.1089/108729102761041083
37. McCombs, J. S., Nichol, M. B., Newman, C. M., & Sclar, D. A. (1994). The costs of interrupting antihypertensive drug therapy in a Medicaid population. Medical Care, 32, 214-226. doi:10.1097/00005650-199403000-00003 http://dx.doi.org/10.1097/00005650-199403000-00003
38. Miller, C. K., Probart, C. K., & Achterberg, C. L. (1997). Knowledge and misconceptions about the food label among women with non-insulin-dependent diabetes mellitus. Diabetes Educator, 23, 425-432. doi:10.1177/014572179702300407 http://dx.doi.org/10.1177/014572179702300407
39. Mitty, J. A., Macalino, G., Taylor, L., Harwell, J. I., & Flanigan, T. P. (2003). Directly observed therapy (DOT) for individuals with HIV: Successes and challenges. Medscape General Medicine, 5, 30.
40. Montgomery, D. A., & Amos, R. J. (1991). Nutrition information needs during cardiac rehabilitation: Perceptions of the cardiac patient and spouse. Journal of the American Dietetic Association, 91, 1078-1083.
41. Morisky, D. E., Green, L. W., & Levine, D. M. (1986). Concurrent and predictive validity of a self-reported measure of medication adherence. Medical Care, 24, 67-74. doi:10.1097/00005650-198601000-00007 http://dx.doi.org/10.1097/00005650-198601000-00007
42. Mukherjee, J. S., Rich, M. L., Socci, A. R., Joseph, J. K., Viru, F. A., Shin, S. S., et al. (2004). Programmes and principles in treatment of multidrug-resistant tuberculosis. Lancet, 363, 474-481. doi:10.1016/S0140-6736(04)15496-2 http://dx.doi.org/10.1016/S0140-6736%2804%2915496-2
43. Mushlin, A. I., & Appel, F. A. (1977). Diagnosing potential noncompliance. Physicians' ability in a behavioral dimension of medical care. Archives of Internal Medicine, 137, 318-321. doi:10.1001/archinte.1977.03630150030010 http://dx.doi.org/10.1001/archinte.1977.03630150030010
44. Nikolaus, T., Kruse, W., Bach, M., Specht-Leible, N., Oster, P., & Schlierf, G. (1996). Elderly patients' problems with medication. An in-hospital and follow-up study. European Journal of Clinical Pharmacology, 49, 255-259. doi:10.1007/BF00226324 http://dx.doi.org/10.1007/BF00226324
45. O'Neil, P. M. (2001). Assessing dietary intake in the management of obesity. Obesity Research, 9 (Suppl. 5), 361S-366S.
46. Parienti, J. J., Massari, V., Descamps, D., Vabret, A., Bouvet, E., Larouze, B., et al. (2004). Predictors of virologic failure and resistance in HIV-infected patients treated with nevirapine-or efavirenz-based antiretroviral therapy. Clinical Infectious Diseases, 38, 1311-1316. doi:10.1086/383572 http://dx.doi.org/10.1086/383572
47. Patrick, D. L., Ramsey, S. D., Spencer, A. C., Kinne, S., Belza, B., & Topolski, T. D. (2001). Economic evaluation of aquatic exercise for persons with osteoarthritis. Medical Care, 39, 413-424. doi:10.1097/00005650-200105000-00002 http://dx.doi.org/10.1097/00005650-200105000-00002
48. Pereira, M. A., FitzerGerald, S. J., Gregg, E. W., Joswiak, M. L., Ryan, W. J., Suminski, R. R., et al. (1997). A collection of physical activity questionnaires for health-related research. Medicine and Science in Sports and Exercise, 29, S1-205.
49. Pratt, R. J., Robinson, N., Loveday, H. P., Pellowe, C. M., Franks, P. J., Hankins, M., et al. (2001). Adherence to antiretroviral therapy: Appropriate use of self-reporting in clinical practice. HIV Clinical Trials, 2, 146-159. doi:10.1310/89E2-XNJL-W107-R2GL http://dx.doi.org/10.1310/89E2-XNJL-W107-R2GL
50. Quittner, A. L., Espelage, D. L., Ievers-Landis, C., & Drotar, D. (2000). Measuring adherence to medical treatments in childhood chronic illness: Considering multiple methods and sources of information. Journal of Clinical Psychology in Medical Settings, 7, 41-54. doi:10.1023/A:1009545319673 http://dx.doi.org/10.1023/A:1009545319673
51. Quittner, A. L., & Opipari, L. C. (1994). Differential treatment of siblings: Interview and diary analyses comparing two family contexts. Child Development, 65, 800-814. doi:10.2307/1131419 http://dx.doi.org/10.2307/1131419
52. Rand, C. S. (2000). "I took the medicine like you told me, doctor": Self-report of adherence with medical regimens. In A. A.Stone, J. S.Turkkan, C. A.Bachrach, J. B.Jobe, H. S.Kurtzman, & V. S.Cain (Eds.), The science of self-report: Implications for research and practice (pp. 257-276). Mahwah, NJ: Erlbaum.
53. Rand, C. S., & Wise, R. A. (1994). Measuring adherence to asthma medication regimens. American Journal of Respiratory and Critical Care Medicine, 149, S69-S76.
54. Rapoff, M. A. (1999). Adherence to pediatric medical regimens. New York: Kluwer Academic.
55. Rauh, M. J., Hovell, M. F., Hofstetter, C. R., Sallis, J. F., & Gleghorn, A. (1992). Reliability and validity of self-reported physical activity in Latinos. International Journal of Epidemiology, 21, 966-971. doi:10.1093/ije/21.5.966 http://dx.doi.org/10.1093/ije/21.5.966
56. Reynolds, L. A., Johnson, S. B., & Silverstein, J. (1990). Assessing daily diabetes management by 24-hour recall interview: The validity of children's reports. Journal of Pediatric Psychology, 15, 493-509. doi:10.1093/jpepsy/15.4.493 http://dx.doi.org/10.1093/jpepsy/15.4.493
57. Richardson, M. T., Ainsworth, B. E., Jacobs, D. R., & Leon, A. S. (2001). Validation of the Stanford 7-day recall to assess habitual physical activity. Annals of Epidemiology, 11, 145-153. doi:10.1016/S1047-2797(00)00190-3 http://dx.doi.org/10.1016/S1047-2797%2800%2900190-3
58. Riekert, K. A., Butz, A. M., Eggleston, P. A., Winkelstein, M., & Rand, C. S. (2003). Caregiver-physician medication concordance and under-treatment of asthma among inner-city children. Pediatrics, 111, e214-e220. doi:10.1542/peds.111.3.e214 http://dx.doi.org/10.1542/peds.111.3.e214
59. Riekert, K. A., & Rand, C. S. (2002). Electronic monitoring of adherence: When is high-tech best? Journal of Clinical Psychology in Medical Settings, 9, 25-34. doi:10.1023/A:1014131928789 http://dx.doi.org/10.1023/A:1014131928789
60. Robinson, D., Woerner, M. G., Alvir, J. M., Bilder, R., Goldman, R., Geisler, S., et al. (1999). Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder. Archives of General Psychiatry, 56, 241-247. doi:10.1001/archpsyc.56.3.241 http://dx.doi.org/10.1001/archpsyc.56.3.241
61. Salas, M., In't Veld, B. A., van der Linden, P. D., Hofman, A., Breteler, M., & Stricker, B. H. (2001). Impaired cognitive function and compliance with antihypertensive drugs in elderly: The Rotterdam Study. Clinical Pharmacology and Therapeutics, 70, 561-566.
62. Sallis, J. F., Haskell, W. L., Wood, P. D., Fortmann, S. P., Rogers, T., Blair, S. N., et al. (1985). Physical activity assessment methodology in the Five-City Project. American Journal of Epidemiology, 121, 91-106.
63. Scarfone, R. J., Capraro, G. A., Zorc, J. J., & Zhao, H. (2002). Demonstrated use of metered-dose inhalers and peak flow meters by children and adolescents with acute asthma exacerbations. Archives of Pediatrics and Adolescent Medicine, 156, 378-383.
64. Schatzkin, A., Kipnis, V., Carroll, R. J., Midthune, D., Subar, A. F., Bingham, S., et al. (2003). A comparison of a food frequency questionnaire with a 24-hour recall for use in an epidemiological cohort study: Results from the biomarker-based Observing Protein and Energy Nutrition (OPEN) study. International Journal of Epidemiology, 32, 1054-1062. doi:10.1093/ije/dyg264 http://dx.doi.org/10.1093/ije/dyg264
65. Schillinger, D., Piette, J., Grumbach, K., Wang, F., Wilson, C., Daher, C., et al. (2003). Closing the loop: Physician communication with diabetic patients who have low health literacy. Archives of Internal Medicine, 163, 83-90. doi:10.1001/archinte.163.1.83 http://dx.doi.org/10.1001/archinte.163.1.83
66. Schoeller, D. A., Ravussin, E., Schutz, Y., Acheson, K. J., Baertschi, P., & Jequier, E. (1986). Energy expenditure by doubly labeled water: Validation in humans and proposed calculation. American Journal of Physiology, 250, R823-R830.
67. Shalansky, S. J., Levy, A. R., & Ignaszewski, A. P. (2004). Self-reported Morisky score for identifying nonadherence with cardiovascular medications. Annals of Pharmacotherapy, 38, 1363-1368. doi:10.1345/aph.1E071 http://dx.doi.org/10.1345/aph.1E071
68. Shrestha, M., Parupia, H., Andrews, B., Kim, S. W., Martin, M. S., Park, D. I., et al. (1996). Metered-dose inhaler technique of patients in an urban ED: Prevalence of incorrect technique and attempt at education. American Journal of Emergency Medicine, 14, 380-384. doi:10.1016/S0735-6757(96)90054-6 http://dx.doi.org/10.1016/S0735-6757%2896%2990054-6
69. Steele, D. J., Jackson, T. C., & Gutmann, M. C. (1990). Have you been taking your pills? The adherence-monitoring sequence in the medical interview. Journal of Family Practice, 30, 294-299.
70. Steiner, J. F., & Prochazka, A. V. (1997). The assessment of refill compliance using pharmacy records: Methods, validity, and applications. Journal of Clinical Epidemiology, 50, 105-116. doi:10.1016/S0895-4356(96)00268-5 http://dx.doi.org/10.1016/S0895-4356%2896%2900268-5
71. Stone, A. A., Turkkan, J. S., Bachrach, C. A., Jobe, J. B., Kurtzman, H. S., & Cain, V. S. (2000). The science of self-report: Implications for research and practice. Mahwah, NJ: Erlbaum.
72. SullivanS. D., KrelingD. H., & HazletT. K. (1990). Noncompliance with medication regimens and subsequent hospitalisations: A literature analysis and cost of hospitalisation estimate. Journal of Research in Pharmaco-Economics, 2, 19-33.
73. Svarstad, B. L., Shireman, T. I., & Sweeney, J. K. (2001). Using drug claims data to assess the relationship of medication adherence with hospitalization and costs. Psychiatric Services, 52, 805-811. doi:10.1176/appi.ps.52.6.805 http://dx.doi.org/10.1176/appi.ps.52.6.805
74. Thrift, A. G., McNeil, J. J., Forbes, A., & Donnan, G. A. (1998). Three important subgroups of hypertensive persons at greater risk of intracerebral hemorrhage. Melbourne Risk Factor Study Group. Hypertension, 31, 1223-1229. doi:10.1161/01.HYP.31.6.1223 http://dx.doi.org/10.1161/01.HYP.31.6.1223
75. Turbi, C., Herrero-Beaumont, G., Acebes, J. C., Torrijos, A., Grana, J., Miguelez, R., et al. (2004). Compliance and satisfaction with raloxifene versus alendronate for the treatment of postmenopausal osteoporosis in clinical practice: An open-label, prospective, nonrandomized, observational study. Clinical Therapeutics, 26, 245-256. doi:10.1016/S0149-2918(04)90023-9 http://dx.doi.org/10.1016/S0149-2918%2804%2990023-9
76. Vitolins, M. Z., Rand, C. S., Rapp, S. R., Ribisl, P. M., & Sevick, M. A. (2000). Measuring adherence to behavioral and medical interventions. Controlled Clinical Trials, 21, 188S-194S. doi:10.1016/S0197-2456(00)00077-5 http://dx.doi.org/10.1016/S0197-2456%2800%2900077-5
77. Washburn, R. A., Jacobsen, D. J., Sonko, B. J., Hill, J. O., & Donnelly, J. E. (2003). The validity of the Stanford seven-day physical activity recall in young adults. Medicine and Science in Sports and Exercise, 35, 1374-1380. doi:10.1249/01.MSS.0000079081.08476.EA http://dx.doi.org/10.1249/01.MSS.0000079081.08476.EA
78. Watts, R. W., McLennan, G., Bassham, I., & el Saadi, O. (1997). Do patients with asthma fill their prescriptions? A primary compliance study. Australian Family Physician, 26(Suppl. 1), S4-S6.
79. Weinstein, A. G., & Cuskey, W. (1985). Theophylline compliance in asthmatic children. Annals of Allergy, 54, 19-24.
80. Wiener, L., Riekert, K., Ryder, C., & Wood, L. V. (2004). Assessing medication adherence in adolescents with HIV when electronic monitoring is not feasible. AIDS Patient Care and STDs, 18, 31-42. doi:10.1089/apc.2004.18.527 http://dx.doi.org/10.1089/apc.2004.18.527
81. Wilbur, J., Chandler, P., & Miller, A. M. (2001). Measuring adherence to a women's walking program. Western Journal of Nursing Research, 23, 8-24. doi:10.1177/01939450122044934 http://dx.doi.org/10.1177/01939450122044934
82. World Health Organization. (2003). Adherence to long-term therapies: Evidence for action (Rep. No. 11500526). Geneva: Author.