In vitro and in vivo antiplasmodial activity and cytotoxicity of extracts of Phyllanthus niruri L. herbs traditionally used to treat malaria in Indonesia

Southeast Asian Journal of Tropical Medicine and Public Health

Volumn 38, Issue 4, 2007, Pages 609-615

  Mustofa, ^a   Sholikhah, Eti Nurwening ^a   Wahyuono, Subagus ^a  

^a GADJAH MADA UNIVERSITY   (Indonesia)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 34548235955     PISSN: 01251562     EISSN: 26975718     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Achmadi UF. Malaria and poverty In Indonesia : 1997-2001 situational review of malaria and poverty in Indonesia. Jakarta: Center for Data and Information, Ministry of Health, Republic of Indonesia, 2003.
2. Anonymous. Traditional medicine of Kalimantan people. Jakarta: Department of Education and Culture, Republic of Indonesia, 1990.
3. Baird JK, Sustriayu Nalim MF, Basri H, et al. Survey of resistance to chloroquine by Plasmodium vivax in Indonesia. Trans R Soc Trop Med Hyg 1996; 90:409-11.
4. Benoit-Vical F, Valentin A, Pélissier Y, et al. In vitro antimalarial activity of vegetal extracts used in West African traditional medicine. Am J Trop Med Hyg 1996; 54: 67-71.
5. Desjardins RE, Canfield CJ, Haynes JD, Chulay JD. Quantitative assessment of antimalarial activity In vitro by a semiautomated microdilution technique. Antimicrob Agents Chemother 1979; 16: 710-8.
6. Dondero TJ Jr, Kosin E, Parsons RE, Tann G, Lumanuaw FH. Preliminary survey for chloroquine resistant malaria parts of Nort Sumatra, Indonesia. Southeast Asian J Trop Med Public Health 1974;5:574-8.
7. Ebisawa I, Fukuyama T. Chloroquine resistance of Plasmodium falciparum in West Irian and East Kalimantan. Ann Trop Med Parasitol 1975; 69: 275-82.
8. Fryauff DJ, Soekartono, Tuti S, et al. Survey resistant in vivo to chloroquine of Plasmodium falciparum and P vivax in North Sulawesi, Indonesia. Trans R Soc Trop Med Hyg 1998; 92: 82-3.
9. Gessler MC, Nkunya MHN, Mwasumbi LB, Heinrich M, Tonner M. Screening Tanzanian medical plants for antimalarial activity. Acta Trop 1994; 55: 65-7.
10. Giridharan P, Sumasundaram ST, Perumal K, et al. Novel substituted methylenedioxy lignan suppresses proliferation of cancer cells by inhibiting and activation of c-myc and caspases leading to apoptosis. Br J Cancer 2002; 87: 98-105.
11. Hukeri VI, Kalyani GA, Kakrani HK. Hypoglycemic activity of flavonoids of Phyllanthus frametus in rats, Fitoterapia 1988; 59: 68-70.
12. Khanna A, Rizvi F, Chander R. Lipid lowering activity of Phyllanthus niruri in hyperlipemic rats. J Ethnopharmacol 2002; 82: 19.
13. Lambros C, Vanderberg JP Synchronisation of Plasmodium falciparum erythrocytic stages in culture. J Parasitol 1979; 64: 418-20.
14. Munoz V, Souvain M, Bourdy G, et al. The search for natural bloactive compounds through a multidisciplinary approach in Bolivia: Part II. Antimalarial activity of some plants used by Mosetena Indians. J Ethnopharmacol 2000; 139-55.
15. Ngatidjan, Laboratory method for toxicology. Yogyakarta: Gadjah Mada University, 1991.
16. O'Neill MJ, Bray DH, Boardman P, Phillipson JD, Warshut DC. Plant as sources of antimalarial drugs part. 1. In vitro test method for the evaluation of crude extracts from plants. Planta Med 1985; 52: 394-8.
17. Peters WJ, Portus JH. Robinson BL. The chemotherapy of rodent malaria XXII. The value of drug-resistant strains of P. berghei in screening for blood schizontisidal activity. Ann Trop Med Parasitol 1975; 69: 155-71.
18. Qian-Cutrone J, Huang S, Trimble J, et al. Niruriside, a new HIV RE/RRE binding inhibitors from Phyllanthus niruri. J Nat Prod 1996; 59: 196-9.
19. Sudarsono, Agus P, Didik G, Subagus W, Imono AD, Ngatidjan. Medicinal plant. Yogyakarta: Research Center for Traditional Medicine, Gadjah Mada University, 1996.
20. Trager W, Jensen JB. Cultivation of malarial parasites. Nature 1978; 273: 621-2.
21. Ueno H, Horie S, Nishi Y, et al. Chemical and pharmaceutical studies on medical plants in Paraguay. Geraniin, an angiotensin-converting enzyme inhibitor from Paraparai Mi Phyllanthus niruri. J Nat Prod 1988; 51: 357-9.
22. Van Huysenn W, Rieckmann KH. Disposable environment chamber for assessing the drug susceptibility of malaria parasites, Trop Med Parasitol 1993: 44: 329-30.
23. WHO. The situation of malaria in the world in 1994. Wkly Epidemiol Rec 1997; 72: 269-92.
24. WHO. Roll Back Malaria. A global partnership. Geneva: World Health Organization, 1998.