Tuning a potassium channel - The caress of the surroundings

Biophysical Journal

Volumn 93, Issue 4, 2007, Pages 1091-1092

  Jordan, Peter C ^a  

^a BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN; POTASSIUM CHANNEL; POTASSIUM ION; PROTON; SODIUM ION;

ARTICLE; BINDING KINETICS; BINDING SITE; DEHYDRATION; DIELECTRIC CONSTANT; ELECTRODE; HYDROGEN BOND; LIGAND BINDING; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; QUANTUM CHEMISTRY; SOLVATION; TEMPERATURE DEPENDENCE; THERMODYNAMICS;

EID: 34548228479     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.107.110205     Document Type: Article

References (11)

1. Hille, B. 2001. Ionic Channels of Excitable Membranes, 3rd ed. Sinauer Associates, Sunderland, MA.
2. + channel-Fab complex at 2.0 Å 9 resolution. Nature. 414:43-48.
3. Bezanilla, F., and C. M. Armstrong. 1972. Negative conductance caused by entry of sodium and cesium ions into the potassium channels of squid axon. J. Gen. Physiol. 60:588-608.
4. Varma, S., and S. B. Rempe. 2006. Coordination numbers of alkali metal ions in aqueous solutions. Biophys. Chem. 124:192-199.
5. Noskov, S. Y., S. Berneche, and B. Roux. 2004. Control of ion selectivity in potassium channels by electrostatic and dynamic properties of carbonyl ligands. Nature. 431:830-834.
6. Eisenman, G. 1962. Cation selective glass electrodes and their mode of operation, Part 2. Biophys J. 2:259-323.
7. +-conducting channel. Nature. 440:570-574.
8. Varma, S., and S. B. Rempe. 2007. Tuning ion coordination architectures to enable selective partitioning. Biophys. J. 93:1093-1099.
9. +-selective family of ion channels using a comprehensive alignment and the KcsA channel structure. Biophys. J. 84:2929-2942.
10. Noskov, S. Y., and B. Roux. 2007. Importance of hydration and dynamics on the selectivity of the KcsA and NaK channels. J. Gen. Physiol. 129:135-143.
11. Bichet, D., Y.-F. Lin, C. A. Ibarra, C. S. Huang, B. A. Yi, Y. N. Jan, and L. Y. Jan. 2004. Evolving potassium channels by means of yeast selection reveals structural elements important for selectivity. Proc. Natl. Acad. Sci. USA. 101:4441-4446.