Hormonal response to buspirone is not impaired in major depression

Human Psychopharmacology

Volumn 22, Issue 6, 2007, Pages 389-395

  Navinés, Ricard ^a,b   Gómez Gil, Esther ^a   Martín Santos, Rocío ^b   Martínez de Osaba, María J ^a   Escolar, Ginés ^a   Gastó, Cristóbal ^a  

^a HOSPITAL CLÍNIC   (Spain)

^b INST MUNIC D INVESTIGACIO MEDICA   (Spain)

Author keywords

5 HT1A receptors; Buspirone; Hormonal response; Major depression

Indexed keywords

BENZODIAZEPINE; BUSPIRONE; CORTICOTROPIN; HYDROCORTISONE; POSTSYNAPTIC RECEPTOR; PROLACTIN; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; DRUG RECHALLENGE; FEMALE; HAMILTON SCALE; HORMONE RESPONSE; HOSPITAL BASED CASE CONTROL STUDY; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; HYPOTHESIS; LOW DRUG DOSE; MAJOR DEPRESSION; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RECEPTOR SENSITIVITY; SCORING SYSTEM; SINGLE DRUG DOSE;

ADOLESCENT; ADRENOCORTICOTROPIC HORMONE; ADULT; ANALYSIS OF VARIANCE; BUSPIRONE; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; DEPRESSIVE DISORDER, MAJOR; FEMALE; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED; PROLACTIN; RECEPTOR, SEROTONIN, 5-HT1A; TREATMENT OUTCOME;

EID: 34548225100     PISSN: 08856222     EISSN: 10991077     Source Type: Journal    
DOI: 10.1002/hup.862     Document Type: Article

References (29)

1. American Psychiatric Association (APA). 1994. Diagnostic and Statistical Manual of Metal Disorders, 4th edn. (DSM-IV). American Psychiatric Association: Washington, DC.
2. Anderson IM, Ware CJ, da Roza Davis JM, Cowen PJ. 1992. 5-HT-mediated prolactin release in major depression. Br J Psychiatry 160: 372-378.
3. Barden N. 2004. Implication or the hypothalamic-pituitary-adrenal axis in the physiopathology of depression. J Psychiatry Neurosci 29: 185-193.
4. Bhagwagar Z, Rabiner EA, Sargent PA, Grasby PM, Cowen PJ. 2004. Persistent reduction in brain serotonin1A receptor binding in recovered depressed men measured by positron emission tomography with [11C]WAY-100635. Mol Psychiatry 9: 386-392.
5. Blier P, de Montigny C. 1994. Advances and trends in the treatment of depression. Trends Pharmacol Sci 15: 220-226.
6. Blier P, Seletti B, Gilbert F, Young SN, Benkelfat C. 2002. Serotonin1A receptor activation and hypothermia in humans: lack of evidence for a presynaptic mediation. Neuropsychopharmacology 27: 301-308.
7. Carney MWP, Roth M, Garside RF. 1965. The diagnosis of depressive syndromes and the prediction of ECT response. Br J Psychiatry 111: 659-674.
8. 1A receptors. Nucl Med Biol 27: 437-439.
9. 1A receptor sensitivity in major depression. A neuroendocrine study with buspirone. Br J Psychiatry 164: 372-379.
10. Dinan G, Scott LV, Thakore J, Naesdal J, Keeling PW. 2001. Impact of cortisol on buspirone stimulated prolactin release: a double-blind placebo-controlled study. Psychoneuroendocrinology 26: 751-756.
11. First M, Spitzer R, Gibbon M, Williams J. 1995. Structured Clinical Interview for DSM-IV Axis I Disorders-Patients Edition (SCID-I/P, Version 2.0). New York State Psychiatric Institute: New York, NY.
12. Gelfin Y, Lerer B, Lesch KP, Gorfine M, Allolio B. 1995. Complex effects of age and gender on hypothermic, adrenocorticotrophic hormone and cortisol responses to ipsapirone challenge in normal subjects. Psychopharmacology 120: 356-364.
13. Gómez E, Catalan R, Navinés R, Gastó C. 2001. Serotonin receptor changes in depression: evidences and limitations. Actas Esp Psiquiatr 29: 186-194.
14. Hamilton M. 1960. A rating scale for depression. J Neurol Neurosurg Psychiatry 23: 56-62.
15. 1A receptor responsivity in unipolar depression. Evaluation of ipsapirone-induced ACTH and cortisol secretion in patients and controls. Biol Psychiatry 28: 620-628.
16. McAllister-Williams RH, Ferrier IN, Young AH. 1998. Mood and neuropsychological function in depression: the role of corticosteroids and serotonin. Psychol Med 28: 573-584.
17. McMillen BA, Matthews RT, Sanghera MK, Shepard PD, German DC. 1983. Dopamine receptor antagonsim by the novel anxiety drug buspirone. J Neurosci 3: 733-738.
18. McMillen BA. 1985. Comparative chronic effects of buspirone or neuroleptics on rat brain dopaminergic neurotransmission. J Neural Transm 64: 1-12.
19. Meltzer HY, Maes M. 1994. Effects of buspirone on plasma prolactin and cortisol levels in major depressed and normal subjects. Biol Psychiatry 33: 316-323.
20. Meltzer HY, Maes M. 1995. Effects of ipsapirone on plasma cortisol and body temperature in major depression. Biol Psychiatry 38: 450-457.
21. Moeller F, Steinberg JL, Fulton M, Kramer G, Petty F. 1994. A preliminary neuroendocrine study with buspirone in major depression. Neuropsychopharmacology 10: 75-83.
22. 1A receptors: from molecular biology to neuropsychiatric symptoms. Actas Esp Psiquiatr 31: 272-283.
23. Navinés R, Gómez-Gil E, Martín-Santos R, Martínez de Osaba MJ, Imaz ML, Gastó C. 2006. An increased hypothermic response to buspirone in patients with major depresión. Psychophamacology 188: 258-260.
24. Porter RJ, Gallagher P, Watson S, Smith MS, Young AH. 2003. Elevated prolactin responses to 1-tryptophan infusion in medication-free depressed patients. Psychopharmacology 169: 77-83.
25. Porter RJ, Gallagher P, Watson S, Young AH. 2004. Corticosteroid-serotonin interactions in depression: a review of the human evidence. Psychopharmacology 173: 1-17.
26. Price LH, Cappiello A, Malison R, et al. 1997. Effects of antiglucocorticoid treatment on 5-HT1A function in depressed patients and healthy subjects. Neuropsychopharmacology 17: 246-256.
27. Riedel WJ, Klaassen T, Griez E, Honing A, Menheere PPCA, van Praag HM. 2002. Dissociable hormonal, cognitive and mood responses to neuroendocrine challenge: evidence for receptor-specific serotoninergic dysregulation in depressed mood. Neuropsychopharmacology 26: 358-367.
28. Shapira B, Newman ME, Gelfin Y, Lerer B. 2000. Blunted temperature and cortisol responses to ipsapirone in major depression: lack of enhancement by electroconvulsive therapy. Psychoneumendocrinology 25: 421-438.
29. Shin Shiah I, Yatham LN, Lam RW, Zis AP. 1998. Cortisol, hypothermic and behavioral responses to ipsapirone in patients with bipolar depression and normal controls. Neuropsychobiology 38: 6-12.