Synthesis of two isotopically labeled 5-HT1B antagonists

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 50, Issue 5-6, 2007, Pages 412-413

  Elmore, Charles S ^a   Hall, James E ^a   Ye, Xiaomei ^a   Heys, J Richard ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

5 HT1B; N heterocyclic iridium complex; Tritiation

Indexed keywords

IRIDIUM COMPOUNDS; ORGANIC COMPOUNDS;

5-HT1B; IRIDIUM COMPLEX; ISOTOPICALLY LABELED; N-HETEROCYCLIC; N-HETEROCYCLIC IRIDIUM COMPLEX; TRITIATION;

SYNTHESIS (CHEMICAL);

AR A 000002; CARBON 14; DEUTERIUM; M 549865; SEROTONIN 1B ANTAGONIST; TRITIUM; UNCLASSIFIED DRUG;

CONFERENCE PAPER; DRUG STRUCTURE; DRUG SYNTHESIS; ISOTOPE LABELING; NUCLEAR MAGNETIC RESONANCE; RADIOCHEMISTRY;

EID: 34548184653     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1164     Document Type: Conference Paper

References (4)

1. Maes M, Meltzer HY. In Psychopharmacology: The Fourth Generation of Progress, Bloom FE, Kepfer DJ (eds). Raven Press: New York, 1995; 933.
2. Blier P, de Montigny C. Trends Pharmaceut Sci 1994; 15: 220.
3. For examples of T-H exchange reactions see Garman RN, Hickey MJ, Kingston LP, McAuley B, Jones JR, Lockley WJS, Mather AN, Wilkinson DJ. J Label Compd Radiopharm 2005; 48: 75 and references therein.
4. Werner T, Berg S, Johansson R. J Label Compd Radiopharm 2004; 47: 175.