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Volumn 56, Issue 11, 2007, Pages 1831-1843

Dendritic cells modified with 6Ckine/IFNγ fusion gene induce specific cytotoxic T lymphocytes in vitro

Author keywords

Chemokines; Cytokines; Dendritic cells; Gene therapy; Tumor immunology

Indexed keywords

ADENOVIRUS VECTOR; CD83 ANTIGEN; CHEMOKINE RECEPTOR CCR7; GAMMA INTERFERON; HYBRID PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 2; RANTES; SECONDARY LYMPHOID TISSUE CHEMOKINE; TRANSCRIPTION FACTOR T BET;

EID: 34548161595     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00262-007-0327-y     Document Type: Article
Times cited : (8)

References (51)
  • 1
    • 0035838981 scopus 로고    scopus 로고
    • Regulation of T cell immunity by dendritic cells
    • Lanzavecchia A, Sallusto F (2001) Regulation of T cell immunity by dendritic cells. Cell 106:263-266
    • (2001) Cell , vol.106 , pp. 263-266
    • Lanzavecchia, A.1    Sallusto, F.2
  • 2
    • 0242329386 scopus 로고    scopus 로고
    • Cellular immunity for cancer chemoimmunotherapy-an overview
    • Mihich E (2003) Cellular immunity for cancer chemoimmunotherapy-an overview. Cancer Immunol Immunother 52:661-662
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 661-662
    • Mihich, E.1
  • 4
    • 33645841055 scopus 로고    scopus 로고
    • Dendritic cell-based tumor vaccines and antigen presentation attenuators
    • Evel-Kabler K, Chen SY (2006) Dendritic cell-based tumor vaccines and antigen presentation attenuators. Mol Ther 13:850-858
    • (2006) Mol Ther , vol.13 , pp. 850-858
    • Evel-Kabler, K.1    Chen, S.Y.2
  • 5
    • 33645531088 scopus 로고    scopus 로고
    • Intrapulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma
    • Yang SC, Batra RK, Hillinger S et al (2006) Intrapulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma. Cancer Res 66:3205-3213
    • (2006) Cancer Res , vol.66 , pp. 3205-3213
    • Yang, S.C.1    Batra, R.K.2    Hillinger, S.3
  • 6
    • 0036377917 scopus 로고    scopus 로고
    • Recombinant adenovirus vector activates and protects human monocyte-derived dendritic cells from apoptosis
    • Lundqvist A, Choudhury A, Nagata T et al (2002) Recombinant adenovirus vector activates and protects human monocyte-derived dendritic cells from apoptosis. Hum Gene Ther 13:1541-1549
    • (2002) Hum Gene Ther , vol.13 , pp. 1541-1549
    • Lundqvist, A.1    Choudhury, A.2    Nagata, T.3
  • 7
    • 0037105694 scopus 로고    scopus 로고
    • Adenovirus infection enhances dendritic cell immunostimulatory properties and induces natural killer and T-cell-mediated tumor protection
    • Miller G, Lahrs S, Pillarisetty VG et al (2002) Adenovirus infection enhances dendritic cell immunostimulatory properties and induces natural killer and T-cell-mediated tumor protection. Cancer Res 62:5260-5266
    • (2002) Cancer Res , vol.62 , pp. 5260-5266
    • Miller, G.1    Lahrs, S.2    Pillarisetty, V.G.3
  • 8
    • 0035893749 scopus 로고    scopus 로고
    • The dynamics of the T-cell antitumor response: Chemokine-secreting dendritic cells can prime tumor-reactive T cells extranodally
    • Kirk CJ, Hartigan-O'Connor D, Mule JJ (2001) The dynamics of the T-cell antitumor response: chemokine-secreting dendritic cells can prime tumor-reactive T cells extranodally. Cancer Res 61:8794-8802
    • (2001) Cancer Res , vol.61 , pp. 8794-8802
    • Kirk, C.J.1    Hartigan-O'Connor, D.2    Mule, J.J.3
  • 9
    • 0035266293 scopus 로고    scopus 로고
    • T cell-dependent antitumor immunity mediated by secondary lymphoid tissue chemokine: Augmentation of dendritic cell-based immunotherapy
    • Kirk CJ, Hartigan-O'Connor D, Nickoloff BJ et al (2001) T cell-dependent antitumor immunity mediated by secondary lymphoid tissue chemokine: augmentation of dendritic cell-based immunotherapy. Cancer Res 61:2062-2070
    • (2001) Cancer Res , vol.61 , pp. 2062-2070
    • Kirk, C.J.1    Hartigan-O'Connor, D.2    Nickoloff, B.J.3
  • 11
    • 0031892090 scopus 로고    scopus 로고
    • A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes
    • Gunn MD, Tangemann K, Tam C et al (1998) A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. Proc Natl Acad Sci USA 95:258-263
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 258-263
    • Gunn, M.D.1    Tangemann, K.2    Tam, C.3
  • 12
    • 0033080779 scopus 로고    scopus 로고
    • Chemokines and the homing of dendritic cells to the T cell areas of lymphoid organs
    • Cyster JG (1999) Chemokines and the homing of dendritic cells to the T cell areas of lymphoid organs. J Exp Med 189:447-450
    • (1999) J Exp Med , vol.189 , pp. 447-450
    • Cyster, J.G.1
  • 13
    • 0031571802 scopus 로고    scopus 로고
    • Isolation and characterization of Exodus-2, a novel C-C chemokine with a unique 37-amino acid carboxyl-terminal extension
    • Hromas R, Kim CH, Klemsz M et al (1997) Isolation and characterization of Exodus-2, a novel C-C chemokine with a unique 37-amino acid carboxyl-terminal extension. J Immunol 159:2554-2558
    • (1997) J Immunol , vol.159 , pp. 2554-2558
    • Hromas, R.1    Kim, C.H.2    Klemsz, M.3
  • 14
    • 0034192078 scopus 로고    scopus 로고
    • Secondary lymphoid tissue chemokine mediates T cell-dependent antitumor responses in vivo
    • Sharma S, Stolina M, Luo J et al (2000) Secondary lymphoid tissue chemokine mediates T cell-dependent antitumor responses in vivo. J Immunol 164:4558-4563
    • (2000) J Immunol , vol.164 , pp. 4558-4563
    • Sharma, S.1    Stolina, M.2    Luo, J.3
  • 15
    • 0035417890 scopus 로고    scopus 로고
    • Secondary lymphoid organ chemokine reduces pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma
    • Sharma S, Stolina M, Zhu L et al (2001) Secondary lymphoid organ chemokine reduces pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma. Cancer Res 61:6406-6412
    • (2001) Cancer Res , vol.61 , pp. 6406-6412
    • Sharma, S.1    Stolina, M.2    Zhu, L.3
  • 16
    • 0026071233 scopus 로고
    • Lymphokine-activated killer cells, natural killer cells and cytokines
    • Perussia B (1991) Lymphokine-activated killer cells, natural killer cells and cytokines. Curr Opin Immunol 3:49-55
    • (1991) Curr Opin Immunol , vol.3 , pp. 49-55
    • Perussia, B.1
  • 17
    • 0030890586 scopus 로고    scopus 로고
    • Cellular responses to interferon-gamma
    • Boehm U, Klamp T, Groot M et al (1997) Cellular responses to interferon-gamma. Annu Rev Immunol 15:749-795
    • (1997) Annu Rev Immunol , vol.15 , pp. 749-795
    • Boehm, U.1    Klamp, T.2    Groot, M.3
  • 18
    • 0035953308 scopus 로고    scopus 로고
    • IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
    • Shankaran V, Ikeda H, Bruce AT et al (2001) IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 410:1107-1111
    • (2001) Nature , vol.410 , pp. 1107-1111
    • Shankaran, V.1    Ikeda, H.2    Bruce, A.T.3
  • 19
    • 0028289170 scopus 로고
    • Antitumor potential of interferon-gamma: Retroviral expression of mouse interferon-gamma cDNA in two kinds of highly metastatic mouse tumor lines reduces their tumorigenicity
    • Yanagihara K, Seyama T, Watanabe Y (1994) Antitumor potential of interferon-gamma: retroviral expression of mouse interferon-gamma cDNA in two kinds of highly metastatic mouse tumor lines reduces their tumorigenicity. Nat Immun 13:102-112
    • (1994) Nat Immun , vol.13 , pp. 102-112
    • Yanagihara, K.1    Seyama, T.2    Watanabe, Y.3
  • 20
    • 0030033708 scopus 로고    scopus 로고
    • Role of neutrophils and lymphocytes in inhibition of a mouse mammary adenocarcinoma engineered to release IL-2, IL-4, IL-7, IL-10, IFN-alpha, IFN-gamma, and TNF-alpha
    • Musiani P, Allione A, Modica A et al (1996) Role of neutrophils and lymphocytes in inhibition of a mouse mammary adenocarcinoma engineered to release IL-2, IL-4, IL-7, IL-10, IFN-alpha, IFN-gamma, and TNF-alpha. Lab Invest 74:146-157
    • (1996) Lab Invest , vol.74 , pp. 146-157
    • Musiani, P.1    Allione, A.2    Modica, A.3
  • 21
    • 0033023734 scopus 로고    scopus 로고
    • Local secretion of IFN-gamma induces an antitumor response: Comparison between T cells plus IL-2 and IFN-gamma transfected tumor cells
    • Sadanaga N, Nagoshi M, Lederer JA et al (1999) Local secretion of IFN-gamma induces an antitumor response: comparison between T cells plus IL-2 and IFN-gamma transfected tumor cells. J Immunother 22:315-323
    • (1999) J Immunother , vol.22 , pp. 315-323
    • Sadanaga, N.1    Nagoshi, M.2    Lederer, J.A.3
  • 22
    • 0035284744 scopus 로고    scopus 로고
    • Differential regulation of human blood dendritic cell subsets by IFNs
    • Ito T, Amakawa R, Inaba M et al (2001) Differential regulation of human blood dendritic cell subsets by IFNs. J Immunol 166:2961-2969
    • (2001) J Immunol , vol.166 , pp. 2961-2969
    • Ito, T.1    Amakawa, R.2    Inaba, M.3
  • 23
    • 0033532531 scopus 로고    scopus 로고
    • Unique features of dendritic cells in IFN-gamma transgenic mice: Relevance to cancer development and therapeutic implications
    • Akbar SM, Kajino K, Tanimoto K et al (1999) Unique features of dendritic cells in IFN-gamma transgenic mice: relevance to cancer development and therapeutic implications. Biochem Biophys Res Commun 259:294-299
    • (1999) Biochem Biophys Res Commun , vol.259 , pp. 294-299
    • Akbar, S.M.1    Kajino, K.2    Tanimoto, K.3
  • 24
    • 0035667197 scopus 로고    scopus 로고
    • Rapid lipopolysaccharide-induced differentiation of CD14(+) monocytes into CD83(+) dendritic cells is modulated under serum-free conditions by exogenously added IFN-gamma and endogenously produced IL-10
    • Koski GK, Lyakh LA, Rice NR (2001) Rapid lipopolysaccharide-induced differentiation of CD14(+) monocytes into CD83(+) dendritic cells is modulated under serum-free conditions by exogenously added IFN-gamma and endogenously produced IL-10. Eur J Immunol 31:3773-3781
    • (2001) Eur J Immunol , vol.31 , pp. 3773-3781
    • Koski, G.K.1    Lyakh, L.A.2    Rice, N.R.3
  • 25
    • 0033591630 scopus 로고    scopus 로고
    • Interleukin 12-dependent interferon gamma production by CD8alpha+ lymphoid dendritic cells
    • Ohteki T, Fukao T, Suzue K et al (1999) Interleukin 12-dependent interferon gamma production by CD8alpha+ lymphoid dendritic cells. J Exp Med 189:1981-1986
    • (1999) J Exp Med , vol.189 , pp. 1981-1986
    • Ohteki, T.1    Fukao, T.2    Suzue, K.3
  • 26
    • 0032553652 scopus 로고    scopus 로고
    • Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation method
    • Mizuguchi H, Kay MA (1998) Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation method. Hum Gene Ther 9:2577-2583
    • (1998) Hum Gene Ther , vol.9 , pp. 2577-2583
    • Mizuguchi, H.1    Kay, M.A.2
  • 27
    • 22044455732 scopus 로고    scopus 로고
    • Adenoviral expression of a truncated S1 subunit of SARS-CoV spike protein results in specific humoral immune responses against SARS-CoV in rats
    • Liu RY, Wu LZ, Huang BJ et al (2005) Adenoviral expression of a truncated S1 subunit of SARS-CoV spike protein results in specific humoral immune responses against SARS-CoV in rats. Virus Res 112:24-31
    • (2005) Virus Res , vol.112 , pp. 24-31
    • Liu, R.Y.1    Wu, L.Z.2    Huang, B.J.3
  • 29
    • 0035400376 scopus 로고    scopus 로고
    • Novel centrifugal method for simple and highly efficient adenovirus-mediated green fluorescence protein gene transduction into human monocyte-derived dendritic cells
    • Nishimura N, Nishioka Y, Shinohara T et al (2001) Novel centrifugal method for simple and highly efficient adenovirus-mediated green fluorescence protein gene transduction into human monocyte-derived dendritic cells. J Immunol Methods 253:113-124
    • (2001) J Immunol Methods , vol.253 , pp. 113-124
    • Nishimura, N.1    Nishioka, Y.2    Shinohara, T.3
  • 30
    • 0035111590 scopus 로고    scopus 로고
    • Enhanced efficiency by centrifugal manipulation of adenovirus-mediated interleukin 12 gene transduction into human monocyte-derived dendritic cells
    • Nishimura N, Nishioka Y, Shinohara T et al (2001) Enhanced efficiency by centrifugal manipulation of adenovirus-mediated interleukin 12 gene transduction into human monocyte-derived dendritic cells. Hum Gene Ther 12:333-346
    • (2001) Hum Gene Ther , vol.12 , pp. 333-346
    • Nishimura, N.1    Nishioka, Y.2    Shinohara, T.3
  • 31
    • 0033083396 scopus 로고    scopus 로고
    • Signs of immaturity of splenic dendritic cells from the autoimmune prone biobreeding rat: Consequences for the in vitro expansion of regulator and effector T cells
    • Delemarre FG, Simons PJ, de Heer HJ et al (1999) Signs of immaturity of splenic dendritic cells from the autoimmune prone biobreeding rat: consequences for the in vitro expansion of regulator and effector T cells. J Immunol 162:1795-1801
    • (1999) J Immunol , vol.162 , pp. 1795-1801
    • Delemarre, F.G.1    Simons, P.J.2    De Heer, H.J.3
  • 32
    • 0034697388 scopus 로고    scopus 로고
    • Distinct subsets of dendritic cells resembling dermal DCs can be generated in vitro from monocytes, in the presence of different serum supplements
    • Duperrier K, Eljaafari A, Dezutter-Dambuyant C et al (2000) Distinct subsets of dendritic cells resembling dermal DCs can be generated in vitro from monocytes, in the presence of different serum supplements. J Immunol Methods 238:119-131
    • (2000) J Immunol Methods , vol.238 , pp. 119-131
    • Duperrier, K.1    Eljaafari, A.2    Dezutter-Dambuyant, C.3
  • 33
    • 1442299843 scopus 로고    scopus 로고
    • Chemokine gene modification of human dendritic cell-based tumor vaccines using a recombinant adenoviral vector
    • Terando A, Roessler B, Mule JJ (2004) Chemokine gene modification of human dendritic cell-based tumor vaccines using a recombinant adenoviral vector. Cancer Gene Ther 11:165-173
    • (2004) Cancer Gene Ther , vol.11 , pp. 165-173
    • Terando, A.1    Roessler, B.2    Mule, J.J.3
  • 34
    • 0030639411 scopus 로고    scopus 로고
    • A comparison of gene transfer methods in human dendritic cells
    • Arthur JF, Butterfield LH, Roth MD et al (1997) A comparison of gene transfer methods in human dendritic cells. Cancer Gene Ther 4:17-25
    • (1997) Cancer Gene Ther , vol.4 , pp. 17-25
    • Arthur, J.F.1    Butterfield, L.H.2    Roth, M.D.3
  • 35
    • 0032984602 scopus 로고    scopus 로고
    • Recombinant adenovirus is an efficient and non-perturbing genetic vector for human dendritic cells
    • Zhong L, Granelli-Piperno A, Choi Y et al (1999) Recombinant adenovirus is an efficient and non-perturbing genetic vector for human dendritic cells. Eur J Immunol 29:964-972
    • (1999) Eur J Immunol , vol.29 , pp. 964-972
    • Zhong, L.1    Granelli-Piperno, A.2    Choi, Y.3
  • 36
    • 0030937585 scopus 로고    scopus 로고
    • Complexes of adenovirus with polycationic polymers and cationic lipids increase the efficiency of gene transfer in vitro and in vivo
    • Fasbender A, Zabner J, Chillon M et al (1997) Complexes of adenovirus with polycationic polymers and cationic lipids increase the efficiency of gene transfer in vitro and in vivo. J Biol Chem 272:6479-6489
    • (1997) J Biol Chem , vol.272 , pp. 6479-6489
    • Fasbender, A.1    Zabner, J.2    Chillon, M.3
  • 37
    • 0031962522 scopus 로고    scopus 로고
    • High efficiency adenovirus-mediated gene transfer to human dendritic cells
    • Dietz AB, Vuk-Pavlovic S (1998) High efficiency adenovirus-mediated gene transfer to human dendritic cells. Blood 91:392-398
    • (1998) Blood , vol.91 , pp. 392-398
    • Dietz, A.B.1    Vuk-Pavlovic, S.2
  • 38
    • 0032943734 scopus 로고    scopus 로고
    • Dendritic cell activation induced by various stimuli, e.g. exposure to microorganisms, their products, cytokines, and simple chemicals as well as adhesion to extracellular matrix
    • Aiba S, Tagami H (1998) Dendritic cell activation induced by various stimuli, e.g. exposure to microorganisms, their products, cytokines, and simple chemicals as well as adhesion to extracellular matrix. J Dermatol Sci 20:1-13
    • (1998) J Dermatol Sci , vol.20 , pp. 1-13
    • Aiba, S.1    Tagami, H.2
  • 39
    • 21244434750 scopus 로고    scopus 로고
    • Modulation of dendritic cell maturation and function by B lymphocytes
    • Bayry J, Lacroix-Desmazes S, Kazatchkine MD et al (2005) Modulation of dendritic cell maturation and function by B lymphocytes. J Immunol 175:15-20
    • (2005) J Immunol , vol.175 , pp. 15-20
    • Bayry, J.1    Lacroix-Desmazes, S.2    Kazatchkine, M.D.3
  • 40
    • 3242663278 scopus 로고    scopus 로고
    • Interferon-gamma is an autocrine mediator for dendritic cell maturation
    • Pan J, Zhang M, Wang J et al (2004) Interferon-gamma is an autocrine mediator for dendritic cell maturation. Immunol Lett 94:141-151
    • (2004) Immunol Lett , vol.94 , pp. 141-151
    • Pan, J.1    Zhang, M.2    Wang, J.3
  • 41
    • 0034670053 scopus 로고    scopus 로고
    • A subset of human monocyte-derived dendritic cells expresses high levels of interleukin-12 in response to combined CD40 ligand and interferon-gamma treatment
    • Mosca PJ, Hobeika AC, Clay TM et al (2000) A subset of human monocyte-derived dendritic cells expresses high levels of interleukin-12 in response to combined CD40 ligand and interferon-gamma treatment. Blood 96:3499-3504
    • (2000) Blood , vol.96 , pp. 3499-3504
    • Mosca, P.J.1    Hobeika, A.C.2    Clay, T.M.3
  • 42
    • 2942557230 scopus 로고    scopus 로고
    • Overexpression of CCL-21/secondary lymphoid tissue chemokine in human dendritic cells augments chemotactic activities for lymphocytes and antigen presenting cells
    • Riedl K, Baratelli F, Batra RK et al (2003) Overexpression of CCL-21/secondary lymphoid tissue chemokine in human dendritic cells augments chemotactic activities for lymphocytes and antigen presenting cells. Mol Cancer 2:35-47
    • (2003) Mol Cancer , vol.2 , pp. 35-47
    • Riedl, K.1    Baratelli, F.2    Batra, R.K.3
  • 43
    • 0033819679 scopus 로고    scopus 로고
    • Recombinant adenovirus induces maturation of dendritic cells via an NF-kappaB-dependent pathway
    • Morelli AE, Larregina AT, Ganster RW et al (2000) Recombinant adenovirus induces maturation of dendritic cells via an NF-kappaB-dependent pathway. J Virol 74:9617-9628
    • (2000) J Virol , vol.74 , pp. 9617-9628
    • Morelli, A.E.1    Larregina, A.T.2    Ganster, R.W.3
  • 44
    • 0038620239 scopus 로고    scopus 로고
    • Optimization of dendritic cell maturation and gene transfer by recombinant adenovirus
    • Miller G, Lahrs S, Shah AB et al (2003) Optimization of dendritic cell maturation and gene transfer by recombinant adenovirus. Cancer Immunol Immunother 52:347-358
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 347-358
    • Miller, G.1    Lahrs, S.2    Shah, A.B.3
  • 45
    • 27144508046 scopus 로고    scopus 로고
    • Dendritic cell maturation, but not CD8+ T cell induction, is dependent on type I IFN signaling during vaccination with adenovirus vectors
    • Hensley SE, Giles-Davis W, McCoy KC et al (2005) Dendritic cell maturation, but not CD8+ T cell induction, is dependent on type I IFN signaling during vaccination with adenovirus vectors. J Immunol 175:6032-6041
    • (2005) J Immunol , vol.175 , pp. 6032-6041
    • Hensley, S.E.1    Giles-Davis, W.2    McCoy, K.C.3
  • 46
    • 0029096916 scopus 로고
    • Activation of dual T cell signaling pathways by the chemokine RANTES
    • Bacon KB, Premack BA, Gardner P et al (1995) Activation of dual T cell signaling pathways by the chemokine RANTES. Science 269:1727-1730
    • (1995) Science , vol.269 , pp. 1727-1730
    • Bacon, K.B.1    Premack, B.A.2    Gardner, P.3
  • 47
    • 0031906135 scopus 로고    scopus 로고
    • RANTES-induced T cell activation correlates with CD3 expression
    • Dairaghi DJ, Soo KS, Oldham ER et al (1998) RANTES-induced T cell activation correlates with CD3 expression. J Immunol 160:426-433
    • (1998) J Immunol , vol.160 , pp. 426-433
    • Dairaghi, D.J.1    Soo, K.S.2    Oldham, E.R.3
  • 48
    • 0033853275 scopus 로고    scopus 로고
    • RANTES activates antigen-specific cytotoxic T lymphocytes in a mitogen-like manner through cell surface aggregation
    • Appay V, Dunbar PR, Cerundolo V et al (2000) RANTES activates antigen-specific cytotoxic T lymphocytes in a mitogen-like manner through cell surface aggregation. Int Immunol 12:1173-1182
    • (2000) Int Immunol , vol.12 , pp. 1173-1182
    • Appay, V.1    Dunbar, P.R.2    Cerundolo, V.3
  • 49
    • 24744434621 scopus 로고    scopus 로고
    • Fas signal links innate and adaptive immunity by promoting dendritic-cell secretion of CC and CXC chemokines
    • Guo Z, Zhang M, Tang H et al (2005) Fas signal links innate and adaptive immunity by promoting dendritic-cell secretion of CC and CXC chemokines. Blood 106:2033-2041
    • (2005) Blood , vol.106 , pp. 2033-2041
    • Guo, Z.1    Zhang, M.2    Tang, H.3
  • 50
    • 0032748338 scopus 로고    scopus 로고
    • Interleukin-12 as an adjuvant for cancer immunotherapy
    • Rodolfo M, Colombo MP (1999) Interleukin-12 as an adjuvant for cancer immunotherapy. Methods 19:114-120
    • (1999) Methods , vol.19 , pp. 114-120
    • Rodolfo, M.1    Colombo, M.P.2
  • 51
    • 8544234990 scopus 로고    scopus 로고
    • Recent developments in the transcriptional regulation of cytolytic effector cells
    • Glimcher LH, Townsend MJ, Sullivan BM et al (2004) Recent developments in the transcriptional regulation of cytolytic effector cells. Nat Rev Immunol 4:900-911
    • (2004) Nat Rev Immunol , vol.4 , pp. 900-911
    • Glimcher, L.H.1    Townsend, M.J.2    Sullivan, B.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.