Prediction of drug degradants using DELPHI: An expert system for focusing knowledge

Molecular Pharmaceutics

Volumn 4, Issue 4, 2007, Pages 539-549

  Pole, David L ^a   Ando, Howard Y ^a,b   Murphy, Sean T ^a  

^a PFIZER INC   (United States)

^b NONE   (United States)

Author keywords

Drug degradation; Expert system; Institutional knowledge; Prediction; Stability; Stress testing

Indexed keywords

1,3,4 THIADIAZOLE DERIVATIVE; AMPICILLIN; ANTHRACENE; BENZENE; CEFUROXIME; CHLORAMPHENICOL; CIMETIDINE; DIAZEPAM; FLUORIDE; FURAN; GLUTETHIMIDE; HYDRAZINE; HYDROXYLAMINE; IMIDAZOLE; LATAMOXEF; LORATADINE; MELPHALAN; NAPHTHALENE; OXAZOLE; PHENOBARBITAL; PYRAZINE; PYRAZOLE; PYRIDAZINE; PYRIDINE; PYRIMIDINE; PYRROLE; TESTOLACTONE; THIAZOLE; THIOPHENE; TRIAMCINOLONE ACETONIDE;

ARTICLE; DELPHI STUDY; DRUG DEGRADATION; DRUG FORMULATION; DRUG STABILITY; DRUG STRUCTURE; MOLECULAR INTERACTION; OXIDATION; PRIORITY JOURNAL;

DRUG STABILITY; MOLECULAR STRUCTURE; PHARMACEUTICAL PREPARATIONS; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; SOFTWARE; SOFTWARE DESIGN;

EID: 34548160518     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp060103+     Document Type: Article

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