The B12/CRP index as a simple prognostic indicator in patients with advanced cancer: A confirmatory study

Annals of Oncology

Volumn 18, Issue 8, 2007, Pages 1395-1399

  Kelly, Laura ^a   White, S ^b   Stone, P C ^b  

^a SURREY AND SUSSEX HEALTHCARE NHS TRUST   (United Kingdom)

^b ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

C reactive protein; Neoplasms; Palliative care; Prognosis; Survival; Vitamin B12

Indexed keywords

C REACTIVE PROTEIN; CYANOCOBALAMIN;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER MORTALITY; CANCER PALLIATIVE THERAPY; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; SURVIVAL TIME; VALIDATION PROCESS; VITAMIN BLOOD LEVEL; BLOOD; KAPLAN MEIER METHOD; MIDDLE AGED; MORTALITY; NEOPLASM; PALLIATIVE THERAPY; PREDICTION AND FORECASTING;

ADULT; AGED; AGED, 80 AND OVER; C-REACTIVE PROTEIN; FEMALE; HUMANS; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; NEOPLASMS; PALLIATIVE CARE; PREDICTIVE VALUE OF TESTS; PROGNOSIS; VITAMIN B 12;

EID: 34548149983     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdm138     Document Type: Article

References (26)

1. Christakis NA, Lamont EB. Extent and determinants of error in doctors' prognoses in terminally ill patients: Prospective cohort study. Br Med J 2000; 320: 469-472.
2. Glare P, Virik K, Jones M et al. A systematic review of physicians' survival predictions in terminally ill cancer patients. Br Med J 2003; 327: 195.
3. Weeks JC, Cook EF, O'Day SJ et al. Relationship between cancer patients' predictions of prognosis and their treatment preferences [erratum appears in JAMA 2000 Jan 12; 283 (2): 203]. JAMA 1998; 279: 1709-1714.
4. Degner LF, Kristjanson LJ, Bowman D et al. Information needs and decisional preferences in women with breast cancer. JAMA 1997; 277: 1485-1492.
5. Blanchard CG, Labrecque MS, Ruckdeschel JC, Blanchard EB. Information and decision-making preferences of hospitalized adult cancer patients. Soc Sci Med 1988; 27: 1139-1145.
6. den Daas N. Estimating length of survival in end-stage cancer: A review of the literature. J Pain Symptom Manage 1995; 10: 548-555.
7. The AM, Hak T, Koeter G, van Der Wal G. Collusion in doctor-patient communication about imminent death: An ethnographic study [comment]. Br Mod J 2000; 321: 1376-1381.
8. Forster LE, Lynn J. Predicting life span for applicants to inpatient hospice. Arch Intern Med 1988; 148: 2540-2543.
9. Maltoni M, Caraceni A, Brunelli C et al. Prognostic factors in advanced cancer patients: Evidence-based clinical recommendation - a study by the Steering Committee at the European Association for Palliative Care. J Clin Oncoll 2005; 23: 6240-6248.
10. Simon R, Altman DG. Statistical aspects of prognostic factor studies in oncology. Br J Cancer 1994; 69: 979-985.
11. Geissbuhler P, Mermillod B, Rapin CH. Elevated serum vitamin B12 levels associated with CRP as a predictive factor of mortally in palliative care cancer patients: A prospective study over five years. J Pain Symptom Manage 2000; 20: 93-103.
12. Vigano A, Dorgan M, Buckingham J et al. Survival prediction in terminal cancer patients: A systematic review of the medical litature. Palliat Med 2000; 14: 363-374.
13. Pirovano M, Maltoni M, Nanni O et al. A new palliative prognostic score: a first step for the staging of terminally ill cancer patients. Italian Multicenter and Study Group on Palliative Care. J Pain Symptom Manage 1999; 17: 231-239.
14. Maltoni M, Nanni O, Pirovano M et al. Successful validation of the palliative prognostic score in terminally ill cancer patients. Italian Multicenter Study Group on Palliative Care. J Pain Symptom Manage 1999; 17: 240-247.
15. Glare P, Virik K. Independent prospective validation of the PaP score in terminally ill patients referred to a hospital-based palliative medicine consultation service. J Pain Symptom Manage 2001; 22: 891-898.
16. Morita T, Tsunoda J, Inoue S, Chihara S. The Palliative Prognostic Index: A scoring system for survival prediction of terminally ill cancer patients. Support Care Cancer 1999; 7: 128-133.
17. Morita T, Tsunoda J, Inoue S, Chihara S. Improved accuracy of physicians' survival prediction for terminally ill cancer patients using the Palliative Prognostic Index. Palliat Med 2001; 15: 419-424.
18. Mahmoud FA, Rivera NI. The role of C-reactive protein as a prognostic indicator in advanced cancer. Curr Oncol Rep 2002; 4: 250-255.
19. Pelliniemi TT, Irjala K, Mattila K et al. Immunoreactive interleukin-6 and acute phase proteins as prognostic factors in multiple myeloma. Finnish Leukemia Group. Blood 1995; 85: 765-771.
20. Tartour E, Dorval T, Mosseri V et al. Serum interleukin 6 and C-reactive protein levels correlate with resistance to IL-2 therapy and poor survival in melanoma patients. Br J Cancer 1994; 69: 911-913.
21. Legouffe E, Rodriguez C, Picot MC et al. C-reactive protein serum level is a valuable and simple prognostic marker in non Hodgkin's lymphoma. Leuk Lymphoma 1998; 31: 351-357.
22. Kodama J, Miyagi Y, Seki N et al. Serum C-reactive protein as a prognostic factor in patients with epithelial ovarian cancer. Eur J Obstet Gynecol Reprod Biol 1999; 82: 107-110.
23. Ljungberg B, Grankvist K, Rasmuson T. Serum acute phase reactants and prognosis in renal cell carcinoma. Cancer 1995; 76: 1435-1439.
24. O'Gorman P, McMillan DC, McArdle CS. Prognostic factors in advanced gastrointestinal cancer patients with weight loss. Nutr Cancer 2000; 37: 36-40.
25. Ermens AAM, Vlasveld LT, Lindemans J. Significance of elevated cobalamin (vitamin B12) levels in blood. Clin Biochem 2003; 36: 585-590.
26. Carmel R, Elsenberg L. Serum vitamin B12 and transcobalamin abnormalities in patients with cancer. Cancer 1977; 40: 1348-1353.