Mechanism of gender-specific differences in aortic stiffness with aging in nonhuman primates

Circulation

Volumn 116, Issue 6, 2007, Pages 669-676

  Qiu, Hongyu ^a   Depre, Christophe ^a   Ghosh, Kaushik ^b   Resuello, Ranillo G ^c   Natividad, Filipinas F ^d   Rossi, Franco ^a   Peppas, Athanasios ^a   Shen, You Tang ^a   Vatner, Dorothy E ^a   Vatner, Stephen F ^a,e  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

^c Simian Conserv Breed/Res Ctr I   (Philippines)

^d ST LUKE S MEDICAL CENTER   (Philippines)

^e UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

Author keywords

Aging; Collagen; Elastin; Gender; Primates

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 8; COLLAGEN;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA DISEASE; AORTA PRESSORECEPTOR; AORTA STIFFNESS; ARTICLE; CONTROLLED STUDY; FEMALE; IN VIVO STUDY; MACACA; MALE; NONHUMAN; PRIORITY JOURNAL; SEX DIFFERENCE; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; YOUNG MODULUS; ANIMAL; AORTA VALVE STENOSIS; BLOOD PRESSURE; COMPARATIVE STUDY; HUMAN; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SEXUAL DEVELOPMENT; THORACIC AORTA;

AGING; ANIMALS; AORTA, THORACIC; AORTIC VALVE STENOSIS; BLOOD PRESSURE; COLLAGEN; FEMALE; HUMANS; MACACA FASCICULARIS; MALE; SEX CHARACTERISTICS;

EID: 34548146362     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.107.689208     Document Type: Article

References (52)

1. Nagai Y, Metter EJ, Earley CJ, Kemper MK, Becker LC, Lakatta EG, Fleg JL. Increased carotid artery intimal-medial thickness in asymptomatic older subjects with exercise-induced myocardial ischemia. Circulation. 1998;98:1504-1509.
2. O'Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK Jr. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults: Cardiovascular Health Study Collaborative Research Group. N Engl J Med. 1999;340:14-22.
3. Loscalzo J, Creager MA, Dzau VJ. Vascular Medicine: A Textbook of Vascular Biology and Diseases. 2nd ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 1996.
4. Hayward CS, Kelly RP, Collins P. The roles of gender, the menopause and hormone replacement on cardiovascular function. Cardiovasc Res. 2000;46:28-49.
5. London GM, Guerin AP, Pannier B, Marchais SJ, Stimpel M. Influence of sex on arterial hemodynamics and blood pressure: role of body height. Hypertension. 1995;26:514-519.
6. Sonesson B, Hansen F, Stale H, Lanne T. Compliance and diameter in the human abdominal aorta: the influence of age and sex. Eur J Vasc Surg. 1993;7:690-697.
7. Schimmler W. Correlation between the pulse wave velocity in the aorto-iliac vessel and age, sex and blood pressure. Angiology. 1996;17:314-322.
8. Bruel A, Oxlund H. Changes in biomechanical properties, composition of collagen and elastin, and advanced glycation end products of the rat aorta in relation to age. Atherosclerosis. 1996;127:155-165.
9. Marque V, Kieffer P, Atkinson J, Lartaud-Idjouadiene I. Elastic properties and composition of the aortic wall in old spontaneously hypertensive rats. Hypertension. 1999;34:415-422.
10. Appt SE. Usefulness of the monkey model to investigate the role soy in postmenopausal women's health. Ilar J. 2004;45:200-211.
11. Kavanagh K, Koudy Williams J, Wagner JD. Naturally occurring menopause in cynomolgus monkeys: changes in hormone, lipid, and carbohydrate measures with hormonal status. J Med Primatol. 2005;34:171-177.
12. Asai K, Kudej RK, Shen Y-T, Yang G-P, Takagi G, Kudej AB, Geng Y-J, Sato N, Nazareno JB, Vatner DE, Natividad F, Bishop SP, Vatner SF. Peripheral vascular endothelial dysfunction and apoptosis in old monkeys. Arterioscler Thromb Vasc Biol. 2000;20:1493-1499.
13. Pagani M, Baig H, Sherman A, Manders WT, Quinn P, Patrick T, Franklin D, Vatner SF. Measurement of multiple simultaneous small dimensions and study of arterial pressure-dimension relations in conscious animals. Am J Physiol. 1978;235:H610-H617.
14. Peterson LH, Jensen RE, Parnell J. Mechanical properties of arteries in vivo. Circ Res. 1960;8:622-639.
15. Kawasaki T, Sasayama S, Yagi S, Asakawa T, Hirai T. Non-invasive assessment of the age related changes in stiffness of major branches of the human arteries. Cardiovasc Res. 1987;21:678-687.
16. Aizawa Y, Kawabe J, Hasebe N, Takehara N, Kikuchi K. Pioglitazone enhances cytokine-induced apoptosis in vascular smooth muscle cells and reduces intimal hyperplasia. Circulation. 2001;104:455-460.
17. Depre C, Shipley GL, Chen W, Han Q, Doenst T, Moore ML, Stepkowski S, Davies PJA, Taegtmeyer H. Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy. Nat Med. 1998;4:1269-1275.
18. Behmoaras J, Osborne-Pellegrin M, Gauguier D, Jacob M-P. Characteristics of the aortic elastic network and related phenotypes in seven inbred rat strains. Am J Physiol Heart Circ Physiol. 2005;288:H769-H777.
19. Reddy GK. AGE-related cross-linking of collagen is associated with aortic wall matrix stiffness in the pathogenesis of drug-induced diabetes in rats. Microvasc Res. 2004;68:132-142.
20. Qiu H, Tian B, Resuello RG, Natividad FF, Peppas A, Shen YT, Vatner DE, Vatner SF, Depre C. Sex-specific regulation of gene expression in the aging monkey aorta. Physiol Genomics. 2007;29:169-180.
21. Lakatta EG. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises, part III: cellular and molecular clues to heart and arterial aging. Circulation. 2003;107:490-497.
22. Sesso HD, Stampfer MJ, Rosner B, Hennekens CH, Gaziano JM, Manson JE, Glynn RJ. Systolic and diastolic blood pressure, pulse pressure, and mean arterial pressure as predictors of cardiovascular disease risk in men. Hypertension. 2000;36:801-807.
23. Zureik M, Touboul PJ, Bonithon-Kopp C, Courbon D, Berr C, Leroux C, Ducimetiere P. Cross-sectional and 4-year longitudinal associations between brachial pulse pressure and common carotid intima-media thickness in a general population: the EVA study. Stroke. 1999;30:550-555.
24. de Simone G, Roman MJ, Koren MJ, Mensah GA, Ganau A, Devereux RB. Stroke volume/pulse pressure ratio and cardiovascular risk in arterial hypertension. Hypertension. 1999;33:800-805.
25. Benetos A, Rudnichi A, Safar M, Guize L. Pulse pressure and cardiovascular mortality in normotensive and hypertensive subjects. Hypertension. 1998;32:560-564.
26. Ferrari AU, Radaelli A, Centola M. Invited review: aging and the cardiovascular system. J Appl Physiol. 2003;95:2591-2597.
27. Benetos A, Adamopoulos C, Bureau J-M, Temmar M, Labat C, Bean K, Thomas F, Pannier B, Asmar R, Zureik M, Safar M, Guize L. Determinants of accelerated progression of arterial stiffness in normotensive subjects and in treated hypertensive subjects over a 6-year period. Circulation. 2002;105:1202-1207.
28. Mackey RH, Sutton-Tyrrell K, Vaitkevicius PV, Sakkinen PA, Lyles MF, Spurgeon HA, Lakatta EG, Kuller LH. Correlates of aortic stiffness in elderly individuals: a subgroup of the Cardiovascular Health Study. Am J Hypertens. 2002;15:16-23.
29. Wilkinson IB, MacCallum H, Rooijmans DF, Murray GD, Cockcroft JR, McKnight JA, Webb DJ. Increased augmentation index and systolic stress in type 1 diabetes mellitus. QJM. 2000;93:441-448.
30. Liao D, Arnett DK, Tyroler HA, Riley WA, Chambless LE, Szklo M, Heiss G. Arterial stiffness and the development of hypertension: the ARIC study. Hypertension. 1999;34:201-206.
31. Cattell MA, Anderson JC, Hasleton PS. Age-related changes in amounts and concentrations of collagen and elastin in normotensive human thoracic aorta. Clin Chim Acta. 1996;245:73-84.
32. Gaballa MA, Jacob CT, Raya TE, Liu J, Simon B, Goldman S. Large artery remodeling during aging: biaxial passive and active stiffness. Hypertension. 1998;32:437-443.
33. Cox RH. Age-related changes in arterial wall mechanics and composition of NIA Fischer rats. Mech Ageing Dev. 1983;23:21-36.
34. Cox RH, Detweiler DK. Comparison of arterial wall properties in young and old racing greyhounds. Mech Ageing Dev. 1988;44:51-67.
35. Maurel E, Shuttleworth CA, Bouissou H. Interstitial collagens and ageing in human aorta. Virchows Arch A Pathol Anat Histopathol. 1987;410:383-390.
36. Takasago T, Nakamura K, Kashiwagi S, Inoue S, Ito H, Takeo K. Analysis of collagen type III by uninterrupted sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting: changes in collagen type III polymorphism in aging rats. Electrophoresis. 1992;13:373-378.
37. Sibinga NES, Foster LC, Hsieh C-M, Perrella MA, Lee W-S, Endege WO, Sage EH, Lee M-E, Haber E. Collagen VIII is expressed by vascular smooth muscle cells in response to vascular injury. Circ Res. 1997;80:532-541.
38. Adiguzel E, Hou G, Mulholland D, Hopfer U, Fukai N, Olsen B, Bendeck M. Migration and growth are attenuated in vascular smooth muscle cells with type VIII collagen-null alleles. Arterioscler Thromb Vasc Biol. 2006;26:56-61.
39. Germain DP, Boutouyrie P, Laloux B, Laurent S. Arterial remodeling and stiffness in patients with pseudoxanthoma elasticum. Arterioscler Thromb Vasc Biol. 2003;23:836-841.
40. Spina M, Garbisa S, Hinnie J, Hunter JC, Serafini-Fracassini A. Age-related changes in composition and mechanical properties of the tunica media of the upper thoracic human aorta. Arteriosclerosis. 1983;3:64-76.
41. Hoffman AS, Grande LA, Park JB. Sequential enzymolysis of human aorta and resultant stress-strain behavior. Biomater Med Devices Artif Organs. 1977;5:121-145.
42. Oxlund H, Andreassen TT. The roles of hyaluronic acid, collagen and elastin in the mechanical properties of connective tissues. J Anat. 1980;131:611-620.
43. Asai K, Kudej RK, Takagi G, Kudej AB, Natividad F, Shen YT, Vatner DE, Vatner SF. Paradoxically enhanced endothelin-B receptor-mediated vasoconstriction in conscious old monkeys. Circulation. 2001;103:2382-2386.
44. Anthony MS, Clarkson TB, Bullock BC, Wagner JD. Soy protein versus soy phytoestrogens in the prevention of diet-induced coronary artery atherosclerosis of male cynomolgus monkeys. Arterioscler Thromb Vasc Biol. 1997;17:2524-2531.
45. Honore EK, Williams JK, Anthony MS, Clarkson TB. Soy isoflavones enhance coronary vascular reactivity in atherosclerotic female macaques. Fertil Steril. 1997;67:148-154.
46. Marsh JD. Phytoestrogens and vascular therapy. J Am Coll Cardiol. 2000;35:1986-1987.
47. van der Schouw YT, Pijpe A, Lebrun CE, Bots ML, Peeters PH, van Staveren WA, Lamberts SW, Grobbee DE. Higher usual dietary intake of phytoestrogens is associated with lower aortic stiffness in postmenopausal women. Arterioscler Thromb Vasc Biol. 2002;22:1316-1322.
48. Michel JB, Heudes D, Michel O, Poitevin P, Philippe M, Scalbert E, Corman B, Levy BI. Effect of chronic ANG I-converting enzyme inhibition on aging processes, II: large arteries. Am J Physiol. 1994;267:R124-R135.
49. Fornieri C, Quaglino D Jr, Mori G. Role of the extracellular matrix in age-related modifications of the rat aorta: ultrastructural, morphometric, and enzymatic evaluations. Arterioscler Thromb. 1992;12:1008-1016.
50. Yin FC, Spurgeon HA, Kallman CH. Age-associated alterations in viscoelastic properties of canine aortic strips. Circ Res. 1983;53:464-472.
51. Mackay EH, Banks J, Sykes B, Lee G. Structural basis for the changing physical properties of human pulmonary vessels with age. Thorax. 1978;33:335-344.
52. Plenz GA, Deng MC, Robenek H, Volker W. Vascular collagens: spotlight on the role of type VIII collagen in atherogenesis. Atherosclerosis. 2003;166:1-11.