Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate ON 01910.Na, a mitotic progression modulator, in human plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 856, Issue 1-2, 2007, Pages 198-204

  Li, Jing ^a   Zhao, Ming ^a   Jimeno, Antonio ^a   He, Ping ^a   Ramana Reddy, M V ^b   Hidalgo, Manuel ^a   Donehower, Ross C ^a   Rudek, Michelle A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

High performance liquid chromatography (HPLC); LC MS MS; Mass spectrometry (MS); ON 01910.Na; Pharmacokinetics

Indexed keywords

ACETONITRILE PROTEIN PRECIPITATION; TANDEM MASS SPECTROMETRY;

ACETONITRILE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS; PLASMA (HUMAN);

PROTEINS;

ACETONITRILE; AMMONIUM ACETATE; ANTINEOPLASTIC AGENT; ON 01910.NA; TEMAZEPAM; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; ARTICLE; CANCER PATIENT; CONTROLLED STUDY; DRUG STABILITY; ELECTROSPRAY; HUMAN; LIQUID CHROMATOGRAPHY; PLASMA; PRECIPITATION; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, LIQUID; GLYCINE; HUMANS; MITOSIS; REFERENCE STANDARDS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFONES; TANDEM MASS SPECTROMETRY;

EID: 34548140060     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.05.047     Document Type: Article

References (2)

1. Gumireddy K., Reddy M.V., Cosenza S.C., Boominathan R., Baker S.J., Papathi N., Jiang J., Holland J., and Reddy E.P. Cancer Cell 7 (2005) 275
2. Donehower R.C., Jimeno A., Li J., Galvin K., Anthony F., Reddy R., Messersmity W., Laheru D., and Baker S.D. J. Clin. Oncol. 24. (2006) abstract #13026