-
2
-
-
30444432840
-
Local proteolytic activity in tumor cell invasion and metastasis
-
Ludwig T: Local proteolytic activity in tumor cell invasion and metastasis. Bioessays 27: 1181-1191, 2005.
-
(2005)
Bioessays
, vol.27
, pp. 1181-1191
-
-
Ludwig, T.1
-
3
-
-
0021941053
-
Cancer metastasis: Experimental approaches, theoretical concepts, and impacts for treatment strategies
-
Schirrmacher V: Cancer metastasis: experimental approaches, theoretical concepts, and impacts for treatment strategies. Adv Cancer Res 43: 1-73, 1985.
-
(1985)
Adv Cancer Res
, vol.43
, pp. 1-73
-
-
Schirrmacher, V.1
-
4
-
-
0035348190
-
Recombinant PAI-1 inhibits angiogenesis and reduces size of LNCaP prostate cancer xenografts in SCID mice
-
Swiercz R, Keck RW, Skrzypczak-Jankun E, Selman SH and Jankun J: Recombinant PAI-1 inhibits angiogenesis and reduces size of LNCaP prostate cancer xenografts in SCID mice. Oncol Rep 8: 463-470, 2001.
-
(2001)
Oncol Rep
, vol.8
, pp. 463-470
-
-
Swiercz, R.1
Keck, R.W.2
Skrzypczak-Jankun, E.3
Selman, S.H.4
Jankun, J.5
-
6
-
-
33644760431
-
A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancer
-
Arlen PM, Gulley JL, Parker C, et al: A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancer. Clin Cancer Res 12: 1260-1269, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1260-1269
-
-
Arlen, P.M.1
Gulley, J.L.2
Parker, C.3
-
7
-
-
33645080175
-
A randomized phase II trial of the matrix metalloproteinase inhibitor BMS-275291 in hormone-refractory prostate cancer patients with bone metastases
-
Lara PN Jr, Stadler WM, Longmate J, et al: A randomized phase II trial of the matrix metalloproteinase inhibitor BMS-275291 in hormone-refractory prostate cancer patients with bone metastases. Clin Cancer Res 12: 1556-1563, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1556-1563
-
-
Lara Jr., P.N.1
Stadler, W.M.2
Longmate, J.3
-
8
-
-
26244435100
-
A phase I and pharmacokinetic study of the selective, non-peptidic inhibitor of matrix metalloproteinase BAY 12-9566 in combination with etoposide and carboplatin
-
Molina JR, Reid JM, Erlichman C, et al: A phase I and pharmacokinetic study of the selective, non-peptidic inhibitor of matrix metalloproteinase BAY 12-9566 in combination with etoposide and carboplatin. Anticancer Drugs 16: 997-1002, 2005.
-
(2005)
Anticancer Drugs
, vol.16
, pp. 997-1002
-
-
Molina, J.R.1
Reid, J.M.2
Erlichman, C.3
-
9
-
-
0141464952
-
A novel form of the plasminogen activator inhibitor created by cysteine mutations extends its half-life: Relevance to cancer and angiogenesis
-
Chorostowska-Wynimko J, Swiercz R, Skrzypczak-Jankun E, Wojtowicz A, Selman SH and Jankun J: A novel form of the plasminogen activator inhibitor created by cysteine mutations extends its half-life: relevance to cancer and angiogenesis. Mol Cancer Ther 2: 19-28, 2003.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 19-28
-
-
Chorostowska-Wynimko, J.1
Swiercz, R.2
Skrzypczak-Jankun, E.3
Wojtowicz, A.4
Selman, S.H.5
Jankun, J.6
-
10
-
-
20144369601
-
Inhibitors of proteases as anticancer drugs
-
Jedinak A and Maliar T: Inhibitors of proteases as anticancer drugs. Neoplasma 52: 185-192, 2005.
-
(2005)
Neoplasma
, vol.52
, pp. 185-192
-
-
Jedinak, A.1
Maliar, T.2
-
11
-
-
33748453503
-
Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones
-
Puli S, Lai JC and Bhushan A: Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones. J Neurooncol 79: 135-142, 2006.
-
(2006)
J Neurooncol
, vol.79
, pp. 135-142
-
-
Puli, S.1
Lai, J.C.2
Bhushan, A.3
-
13
-
-
33644694466
-
Plasminogen activator inhibitor-1 (PAI-1) gene transfection inhibits the liver metastasis of pancreatic cancer by preventing angiogenesis
-
Inoue M, Sawada T, Uchima Y, et al: Plasminogen activator inhibitor-1 (PAI-1) gene transfection inhibits the liver metastasis of pancreatic cancer by preventing angiogenesis. Oncol Rep 14: 1445-1451, 2005.
-
(2005)
Oncol Rep
, vol.14
, pp. 1445-1451
-
-
Inoue, M.1
Sawada, T.2
Uchima, Y.3
-
15
-
-
0025227854
-
Structure-function studies of the SERPIN plasminogen activator inhibitor type 1. Analysis of chimeric strained loop mutants
-
Lawrence DA, Strandberg L, Ericson J and Ny T: Structure-function studies of the SERPIN plasminogen activator inhibitor type 1. Analysis of chimeric strained loop mutants. J Biol Chem 265: 20293-20301, 1990.
-
(1990)
J Biol Chem
, vol.265
, pp. 20293-20301
-
-
Lawrence, D.A.1
Strandberg, L.2
Ericson, J.3
Ny, T.4
-
16
-
-
0029317438
-
Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition
-
Tucker HM, Mottonen J, Goldsmith EJ and Gerard RD: Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition. Nat Struct Biol 2: 442-445, 1995.
-
(1995)
Nat Struct Biol
, vol.2
, pp. 442-445
-
-
Tucker, H.M.1
Mottonen, J.2
Goldsmith, E.J.3
Gerard, R.D.4
-
17
-
-
11844272703
-
Expression of urokinase plasminogen activator, its receptor and type-1 inhibitor in malignant and benign prostate tissue
-
Usher PA, Thomsen OF, Iversen P, et al: Expression of urokinase plasminogen activator, its receptor and type-1 inhibitor in malignant and benign prostate tissue. Int J Cancer 113: 870-880, 2005.
-
(2005)
Int J Cancer
, vol.113
, pp. 870-880
-
-
Usher, P.A.1
Thomsen, O.F.2
Iversen, P.3
-
18
-
-
0033981473
-
The plasminogen activation system in tumor growth, invasion, and metastasis
-
Andreasen PA, Egelund R and Petersen HH: The plasminogen activation system in tumor growth, invasion, and metastasis. Cell Mol Life Sci 57: 25-40, 2000.
-
(2000)
Cell Mol Life Sci
, vol.57
, pp. 25-40
-
-
Andreasen, P.A.1
Egelund, R.2
Petersen, H.H.3
-
19
-
-
16844377832
-
Historical analysis of PAI-1 from its discovery to its potential role in cell motility and disease
-
Dellas C and Loskutoff DJ: Historical analysis of PAI-1 from its discovery to its potential role in cell motility and disease. Thromb Haemost 93: 631-640, 2005.
-
(2005)
Thromb Haemost
, vol.93
, pp. 631-640
-
-
Dellas, C.1
Loskutoff, D.J.2
-
20
-
-
0025347305
-
Alteration of serpin specificity by a protein co-factor. Vitronectin endows plasminogen activator inhibitor 1 with thrombin inhibitory properties
-
Ehrlich HJ, Gebbink RK, Keijer J, Linders M, Preissner KT and Pannekoek H: Alteration of serpin specificity by a protein co-factor. Vitronectin endows plasminogen activator inhibitor 1 with thrombin inhibitory properties. J Biol Chem 265: 13029-13035, 1990.
-
(1990)
J Biol Chem
, vol.265
, pp. 13029-13035
-
-
Ehrlich, H.J.1
Gebbink, R.K.2
Keijer, J.3
Linders, M.4
Preissner, K.T.5
Pannekoek, H.6
-
21
-
-
0023637141
-
Activation of human endothelial cell-type plasminogen activator inhibitor (PAI-1) by negatively charged phospholipids
-
Lambers JW, Cammenga M, Konig BW, Mertens K, Pannekoek H and van Mourik JA: Activation of human endothelial cell-type plasminogen activator inhibitor (PAI-1) by negatively charged phospholipids. J Biol Chem 262: 17492-17496, 1987.
-
(1987)
J Biol Chem
, vol.262
, pp. 17492-17496
-
-
Lambers, J.W.1
Cammenga, M.2
Konig, B.W.3
Mertens, K.4
Pannekoek, H.5
Van Mourik, J.A.6
-
22
-
-
33845665891
-
Global functional analysis of nucleophosmin in Taxol response, cancer, chromatin regulation, and ribosomal DNA transcription
-
Bergstralh DT, Conti BJ, Moore CB, Brickey WJ, Taxman DJ and Ting JP: Global functional analysis of nucleophosmin in Taxol response, cancer, chromatin regulation, and ribosomal DNA transcription. Exp Cell Res 313: 65-76, 2007.
-
(2007)
Exp Cell Res
, vol.313
, pp. 65-76
-
-
Bergstralh, D.T.1
Conti, B.J.2
Moore, C.B.3
Brickey, W.J.4
Taxman, D.J.5
Ting, J.P.6
-
23
-
-
0347480218
-
The translationally controlled tumour protein (TCTP)
-
Bommer UA and Thiele BJ: The translationally controlled tumour protein (TCTP). Int J Biochem Cell Biol 36: 379-385, 2004.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 379-385
-
-
Bommer, U.A.1
Thiele, B.J.2
-
24
-
-
66749116183
-
The PyMOL molecular graphics system
-
v. 0.98.
-
De Lano WL: The PyMOL molecular graphics system. PyMOL v. 0.98., 2005.
-
(2005)
PyMOL
-
-
De Lano, W.L.1
-
25
-
-
0031473847
-
SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
-
Guex N and Peitsch MC: SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 18: 2714-2723, 1997.
-
(1997)
Electrophoresis
, vol.18
, pp. 2714-2723
-
-
Guex, N.1
Peitsch, M.C.2
-
26
-
-
0001679473
-
ALIGN: A program to superimpose protein coordinates, accounting for insertions and deletions
-
Cohen GE: ALIGN: a program to superimpose protein coordinates, accounting for insertions and deletions. J Appl Crystallograph 30: 1160-1161, 1997.
-
(1997)
J Appl Crystallograph
, vol.30
, pp. 1160-1161
-
-
Cohen, G.E.1
-
27
-
-
0037332097
-
Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases
-
Amagata T, Whitman S, Johnson TA, et al: Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases. J Nat Prod 66: 230-235, 2003.
-
(2003)
J Nat Prod
, vol.66
, pp. 230-235
-
-
Amagata, T.1
Whitman, S.2
Johnson, T.A.3
-
28
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
29
-
-
12244267707
-
Proteomic analysis of early melanosomes: Identification of novel melanosomal proteins
-
Basrur V, Yang F, Kushimoto T, et al: Proteomic analysis of early melanosomes: identification of novel melanosomal proteins. J Proteome Res 2: 69-79, 2003.
-
(2003)
J Proteome Res
, vol.2
, pp. 69-79
-
-
Basrur, V.1
Yang, F.2
Kushimoto, T.3
-
30
-
-
0025844741
-
Malignant transformation of human fibroblasts correlates with increased activity of receptor-bound plasminogen activator
-
Jankun J, Maher VM and McCormick JJ: Malignant transformation of human fibroblasts correlates with increased activity of receptor-bound plasminogen activator. Cancer Res 51: 1221-1226, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 1221-1226
-
-
Jankun, J.1
Maher, V.M.2
McCormick, J.J.3
-
31
-
-
0025905669
-
Kinetic analysis of the interaction between type 1 plasminogen activator inhibitor and vitronectin and evidence that the bovine inhibitor binds to a thrombin-derived amino-terminal fragment of bovine vitronectin
-
Seiffert D and Loskutoff DJ: Kinetic analysis of the interaction between type 1 plasminogen activator inhibitor and vitronectin and evidence that the bovine inhibitor binds to a thrombin-derived amino-terminal fragment of bovine vitronectin. Biochim Biophys Acta 1078: 23-30, 1991.
-
(1991)
Biochim Biophys Acta
, vol.1078
, pp. 23-30
-
-
Seiffert, D.1
Loskutoff, D.J.2
-
32
-
-
0028281746
-
Engineering plasminogen activator inhibitor 1 mutants with increased functional stability
-
Lawrence DA, Olson ST, Palaniappan S and Ginsburg D: Engineering plasminogen activator inhibitor 1 mutants with increased functional stability. Biochemistry 33: 3643-3648, 1994.
-
(1994)
Biochemistry
, vol.33
, pp. 3643-3648
-
-
Lawrence, D.A.1
Olson, S.T.2
Palaniappan, S.3
Ginsburg, D.4
-
33
-
-
33644941760
-
Plasminogen activator inhibitor-1 is locked in active conformation and polymerizes upon binding ligands neutralizing its activity
-
Jankun J, Specht Z, Szkudlarek M, et al: Plasminogen activator inhibitor-1 is locked in active conformation and polymerizes upon binding ligands neutralizing its activity. Int J Mol Med 17: 437-447, 2006.
-
(2006)
Int J Mol Med
, vol.17
, pp. 437-447
-
-
Jankun, J.1
Specht, Z.2
Szkudlarek, M.3
-
34
-
-
0141539503
-
Purification of recombinant plasminogen activator inhibitor-1 in the active conformation by refolding from inclusion bodies
-
Lee HJ and Im H: Purification of recombinant plasminogen activator inhibitor-1 in the active conformation by refolding from inclusion bodies. Protein Expr Purif 31: 99-107, 2003.
-
(2003)
Protein Expr Purif
, vol.31
, pp. 99-107
-
-
Lee, H.J.1
Im, H.2
-
35
-
-
1542390500
-
The reactive-center loop of active PAI-1 is folded close to the protein core and can be partially inserted
-
Hagglof P, Bergstrom F, Wilczynska M, Johansson LB and Ny T: The reactive-center loop of active PAI-1 is folded close to the protein core and can be partially inserted. J Mol Biol 335: 823-832, 2004.
-
(2004)
J Mol Biol
, vol.335
, pp. 823-832
-
-
Hagglof, P.1
Bergstrom, F.2
Wilczynska, M.3
Johansson, L.B.4
Ny, T.5
-
36
-
-
33747347557
-
A novel function of plasminogen activator inhibitor-1 in modulation of the AKT pathway in wild-type and plasminogen activator inhibitor-1-deficient endothelial cells
-
Balsara RD, Castellino FJ and Ploplis VA: A novel function of plasminogen activator inhibitor-1 in modulation of the AKT pathway in wild-type and plasminogen activator inhibitor-1-deficient endothelial cells. J Biol Chem 281: 22527-22536, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 22527-22536
-
-
Balsara, R.D.1
Castellino, F.J.2
Ploplis, V.A.3
-
37
-
-
0037416209
-
Plasminogen activator inhibitor-1 detaches cells from extracellular matrices by inactivating integrins
-
Czekay RP, Aertgeerts K, Curriden SA and Loskutoff DJ: Plasminogen activator inhibitor-1 detaches cells from extracellular matrices by inactivating integrins. J Cell Biol 160: 781-791, 2003.
-
(2003)
J Cell Biol
, vol.160
, pp. 781-791
-
-
Czekay, R.P.1
Aertgeerts, K.2
Curriden, S.A.3
Loskutoff, D.J.4
-
38
-
-
0035929679
-
Acute phase protein alpha 1-acid glycoprotein interacts with plasminogen activator inhibitor type 1 and stabilizes its inhibitory activity
-
Boncela J, Papiewska I, Fijalkowska I, Walkowiak B and Cierniewski CS: Acute phase protein alpha 1-acid glycoprotein interacts with plasminogen activator inhibitor type 1 and stabilizes its inhibitory activity. J Biol Chem 276: 35305-35311, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 35305-35311
-
-
Boncela, J.1
Papiewska, I.2
Fijalkowska, I.3
Walkowiak, B.4
Cierniewski, C.S.5
-
40
-
-
0035266314
-
Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/ anaplastic lymphoma kinase-mediated lymphomagenesis
-
Slupianek A, Nieborowska-Skorska M, Hoser G, et al: Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/anaplastic lymphoma kinase-mediated lymphomagenesis. Cancer Res 61: 2194-2199, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 2194-2199
-
-
Slupianek, A.1
Nieborowska-Skorska, M.2
Hoser, G.3
-
41
-
-
30344480772
-
Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis
-
Ii M, Yamamoto H, Adachi Y, Maruyama Y and Shinomura Y: Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis. Exp Biol Med 231: 20-27, 2006.
-
(2006)
Exp Biol Med
, vol.231
, pp. 20-27
-
-
Ii, M.1
Yamamoto, H.2
Adachi, Y.3
Maruyama, Y.4
Shinomura, Y.5
-
42
-
-
7444246058
-
Translationally controlled tumor protein is a target of tumor reversion
-
Tuynder M, Fiucci G, Prieur S, et al: Translationally controlled tumor protein is a target of tumor reversion. Proc Natl Acad Sci USA 101: 15364-15369, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15364-15369
-
-
Tuynder, M.1
Fiucci, G.2
Prieur, S.3
-
43
-
-
0037069412
-
Biological models and genes of tumor reversion: Cellular reprogramming through tpt1/TCTP and SIAH-1
-
Tuynder M, Susini L, Prieur S, et al: Biological models and genes of tumor reversion: cellular reprogramming through tpt1/TCTP and SIAH-1. Proc Natl Acad Sci USA 99: 14976-14981, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14976-14981
-
-
Tuynder, M.1
Susini, L.2
Prieur, S.3
-
44
-
-
3543091527
-
Mitogenic signaling of urokinase receptor-deficient kidney fibroblasts: Actions of an alternative urokinase receptor and LDL receptor-related protein
-
Zhang G, Cai X, Lopez-Guisa JM, Collins SJ and Eddy AA: Mitogenic signaling of urokinase receptor-deficient kidney fibroblasts: actions of an alternative urokinase receptor and LDL receptor-related protein. J Am Soc Nephrol 15: 2090-2102, 2004.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2090-2102
-
-
Zhang, G.1
Cai, X.2
Lopez-Guisa, J.M.3
Collins, S.J.4
Eddy, A.A.5
|