Synthesis and pharmacological effects of new, N-substituted soft anticholinergics based on glycopyrrolate

Journal of Pharmacy and Pharmacology

Volumn 57, Issue 11, 2005, Pages 1427-1435

  Ji, F ^a   Wu, W ^a   Dai, X ^a   Mori, N ^a   Wu, J ^a   Buchwald, P ^b   Bodor, Nicholas ^a,b  

^a UNIVERSITY OF FLORIDA HEALTH   (United States)

^b IVAX Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPENTYLMANDELIC ACID; CYCLOPENTYLPHENYLHYDROXYACETOXY 1 METHYL 1 METHOXYCARBONYLPYRROLIDINIUM BROMIDE; GLYCOPYRRONIUM BROMIDE; MANDELIC ACID DERIVATIVE; METHYL CYCLOPENTYLMANDELATE; MUSCARINIC RECEPTOR; N METHYL 3 PYRROLIDINYL CYCLOPENTYLMANDELATE; UNCLASSIFIED DRUG; CHOLINERGIC RECEPTOR BLOCKING AGENT; DRUG DERIVATIVE; MYDRIATIC AGENT;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG HALF LIFE; DRUG POTENCY; DRUG SAFETY; DRUG SENSITIVITY; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER METABOLISM; MYDRIASIS; NONHUMAN; RABBIT; STEREOSPECIFICITY; ANIMAL; CELL LINE; DRUG DESIGN; GENETICS; GUINEA PIG; MALE; METABOLISM; MOLECULAR CLONING; MUSCLE CONTRACTION; PH; PUPIL; RAT; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TIME;

ANIMALS; CELL LINE; CHOLINERGIC ANTAGONISTS; CLONING, MOLECULAR; DRUG DESIGN; DRUG STABILITY; GLYCOPYRROLATE; GUINEA PIGS; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MUSCLE CONTRACTION; MYDRIATICS; PUPIL; RABBITS; RATS; RECEPTORS, MUSCARINIC; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

EID: 34548057235     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.57.11.0008     Document Type: Article

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