Evaluation of the effect of Ginkgo biloba extract (EGb 761) on the myenteric plexus of the small intestine of Wistar rats

Journal of Gastroenterology

Volumn 42, Issue 8, 2007, Pages 624-630

  Carla, Larissa ^a   Schneider, Lauer ^a   Perez, Glasiella Gonsales ^a   Banzi, Silmara Reis ^b   Zanoni, Jacqueline Nelisis ^a   Raquel, Maria ^a   Natali, Maŗal ^a   Buttow, Nilza Cristina ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Aging; Ginkgo biloba; Myentericplexus; Neuroprotection

Indexed keywords

ANTIOXIDANT; GINKGO BILOBA EXTRACT; MYOSIN V;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; CELL AGING; CELL DENSITY; CELL POPULATION; CONTROLLED STUDY; DRUG EFFICACY; ILEUM; IMMUNOHISTOCHEMISTRY; JEJUNUM; MALE; MYENTERIC PLEXUS; NERVE CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; SMALL INTESTINE;

AGING; ANIMALS; CELL COUNT; CELL SIZE; DOSE-RESPONSE RELATIONSHIP, DRUG; FOLLOW-UP STUDIES; GINKGO BILOBA; ILEUM; IMMUNOHISTOCHEMISTRY; JEJUNUM; MALE; MYENTERIC PLEXUS; PLANT EXTRACTS; RATS; RATS, WISTAR;

EID: 34548033045     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-007-2079-z     Document Type: Article

References (43)

1. S Yoon C Yun A Chung 2002 Dose effect of oxidative stress on signal transduction in aging Mech Ageing Dev 123 1539-601 10.1016/ S0047-6374(02)00095-7
2. Y Ni B Zhao J Hou W Xin 1996 Preventive effect of Ginkgo biloba extract on apoptosis in rat cerebellar neuronal cells induced by hydroxyl radicals Neurosci Lett 214 115-8 8878097 10.1016/0304-3940(96)12897-4 1:CAS:528:DyaK28XlsFyisb0%3D
3. M Ellnain-Wojtaszek Z Kruczynski J Kasprzak 2003 Investigation of the free radical scavenging activity of Ginkgo biloba L. leaves Fitoterapia 74 1-6 12628386 10.1016/S0367-326X(02)00306-4 1:CAS:528:DC%2BD3sXhs1Kktbk%3D
4. SB Garcia J Paula GS Giovanette F Zenh EM Ramalho S Zucoloto 1999 Nitric oxide is involved in the lesions of the peripheral autonomic neurons observed in the acute phase of experimental Tripanosoma cruzi infection Exp Parasitol 93 191-7 10600444 10.1006/expr.1999.4451 1:CAS:528:DyaK1MXnvFaqsbs%3D
5. PG Pietta 2000 Flavonoids as antioxidants J Nat Prod 63 1035-42 10924197 10.1021/np9904509 1:CAS:528:DC%2BD3cXjsFOrsrY%3D
6. Y Luo JV Smith V Paramasivam A Burdick KJ Curry JP Buford 2002 Inhibition of amyloid-B aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761 Proc Natl Acad Sci USA 99 12197-202 12213959 10.1073/pnas.182425199 1:CAS:528:DC%2BD38XntlCksro%3D
7. JV Smith AJ Burdick P Golik I Khan D Wallace Y Luo 2002 Anti-apoptotic properties of Ginkgo biloba extract EGb 761 in differentiated PC12 cells Cell Mol Biol 48 699-707 12396082 1:CAS:528:DC%2BD38XotVGmu74%3D
8. H Fan Z Wang B Cheng 2006 Effects of Ginkgo biloba extract on lipid peroxidation and apoptosis after spinal cord ischemia/reperfusion in rabbits Chin J Traumatol 9 77-81 16533431
9. JV Smith Y Luo 2004 Studies on molecular mechanisms of Ginkgo biloba extract Appl Microbiol Biotechnol 64 465-72 14740187 10.1007/ s00253-003-1527-9 1:CAS:528:DC%2BD2cXjtFyis74%3D
10. E Pretner H Amri W Li R Brown CS Lin E Makariou 2006 Cancer-related overexpression of the peripheral-type benzodiazepine receptor and cytostatic anticancer effects of Ginkgo biloba extract (Egb 761) Anticancer Res 26 9-22 16475673 1:CAS:528:DC%2BD28Xhs1ahsb4%3D
11. B Ahlemeyer J Krieglstein 2003 Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease Pharmacopsychiatry 36 Suppl 1 S8-14 13130383 1:CAS:528:DC%2BD3sXnvVSlsbc%3D
12. FV DeFeudis K Drie 2000 Ginkgo biloba extract (EGb 761) and CNS functions: Basic studies and clinical applications Curr Drug Targets 1 25-58 11475535 10.2174/1389450003349380 1:CAS:528:DC%2BD3cXlt1WhtL4%3D
13. K Gohil L Packer 2002 Global gene expression analysis identifies cell and tissue specific actions of Ginkgo biloba extract, EGb 761 Cell Mol Biol 48 625-31 12396072 1:CAS:528:DC%2BD38XotVGmur4%3D
14. S Nishida H Satoh 2005 Age-related changes in the vasodilating actions of Ginkgo biloba extract and its main constituent, bilobalide, in rat aorta Clin Chim Acta 354 141-6 15748610 10.1016/j.cccn.2004.11.030 1:CAS:528:DC%2BD2MXhvVClsr8%3D
15. G Calapai A Crupi F Firenzuoli MC Marciano F Squadrito G Inferrera 2000 Neuroprotective effects of Ginkgo biloba extract in brain ischemia are mediated by inhibition of nitric oxide synthesis Life Sci 67 2673-83 11105983 10.1016/S0024-3205(00)00858-4 1:CAS:528:DC%2BD3cXnslais78%3D
16. JN Zanoni NC Buttow RB Bazotte MH Miranda-Neto 2003 Evaluation of the population of NADPH-diaphorase-stained and myosin-V myenteric neurons in the ileum of chronically streptozotocin-diabetic rats treated with ascorbic acid Auton Neurosci 104 32-8 12559201 10.1016/ S1566-0702(02)00266-7 1:CAS:528:DC%2BD3sXitV2js7o%3D
17. RM Santer DM Baker 1988 Enteric neuron numbers and sizes in Auerbach's plexus in the small and large intestine of adult and aged rats J Auton Nerv Syst 25 59-67 3225382 10.1016/0165-1838(88)90008-2 1:STN:280:BiaC2c%2FhsFw%3D
18. RJ Johnson M Schemann RM Santer T Cowen 1998 The effects of age on the overall population and on sub-populations of myenteric neurons in the rat small intestine J Anat 192 479-88 9723975 10.1046/ j.1469-7580.1998.19240479.x
19. RJ Phillips TL Powley 2001 As the gut ages: Timetables for aging of innervation vary by organ in the Fischer 344 rat J Comp Neurol 34 358-77 10.1002/cne.1182
20. RJ Phillips EJ Kieffer TL Powley 2003 Aging of the myenteric plexus: neuronal loss is specific to cholinergic neurons Auton Neurosci 106 69-83 12878075 10.1016/S1566-0702(03)00072-9
21. JP Schoffen A Soares P de Freitas NC Buttow MR Natali 2005 Effects of a hypoproteic diet on myosin-V immunostained myenteric neurons and the proximal colon wall of aging rats Auton Neurosci 122 77-83 16199208 10.1016/j.autneu.2005.08.005 1:CAS:528:DC%2BD2MXhtFeiu7jE
22. HJ Cooke 1986 Neurobiology of the intestinal mucosa Gastroenterology 90 1057-81 2419199 1:CAS:528:DyaL28XitF2itL0%3D
23. EM Espreafico RE Cheney M Matteoli AAC Nascimento P De Camilli RE Larson 1992 Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains J Cell Biol 119 1541-57 1469047 10.1083/jcb.119.6.1541 1:CAS:528:DyaK3sXltlelu78%3D
24. IW McLean PK Nakane 1974 Periodate-lysine-paraformaldehyde fixative. A new fixative for immunoelectron microscopy J Histochem Cytochem 22 1077-83 4374474 1:CAS:528:DyaE2MXivVWlug%3D%3D
25. JN Zanoni P De Freitas RV Pereira MA Dos Santos Pereira MH De Miranda Neto 2005 Effects of supplementation with ascorbic acid for a period of 120 days on the myosin-V and NADPHd positive myenteric neurons of the ileum of rats Anat Histol Embryol 34 149-53 15929728 10.1111/ j.1439-0264.2005.00584.x 1:STN:280:DC%2BD2MzkvFamug%3D%3D
26. Marese ACM, Freitas P, Natali MRM. Alterations of the number and the profile of myenteric neurons of wistar rats promoted by age. Neurosci Basic Clin 2007 DOI:10.1016/J2007;05;003
27. M Hanani Y Fellig R Udassin H Freund 2004 Age-related changes in the morphology of the myenteric plexus of the human colon Auton Neurosci 113 71-8 15296797 10.1016/j.autneu.2004.05.007
28. SB Garcia MMP Demarzo WS Vinhadeli MA Llorach-Velludo J Zoteli CFPS Herrero 2002 No reduction with ageing of the number of myenteric neurons in benzalkonium chloride treated rats Neurosci Lett 331 66-8 12359325 10.1016/S0304-3940(02)00832-7 1:CAS:528:DC%2BD38XnsVajtbo%3D
29. I Gavazzi T Cowen 1996 Can the neurotrophic hypothesis explain degeneration and loss of plasticity in mature and ageing autonomic nerves? J Auton Nerv Syst 58 1-10 8740653 10.1016/0165-1838(95)00111-5 1:CAS:528:DyaK28XjtVynsLc%3D
30. RR Souza HB Moratelli N Borges EA Liberti 1993 Age-induced nerve cell loss in the myenteric plexus of the small intestine in man Gerontology 39 183-8 8244045
31. G Gabella 1976 Structure of the autonomic nervous system Chapman & Hall London
32. JB Furness M Costa 1980 Types of nerves in the enteric nervous system Neuroscience 5 1-20 6154268 10.1016/0306-4522(80)90067-6 1:CAS:528:DyaL3cXht1Gnu7k%3D
33. APN Majundar R Jaszewski M Dubick 1997 Effect of aging on the gastrointestinal tract and the pancreas Proc Soc Exp Biol Med 215 134-44
34. B Ahlemeyer V Junker R Huhne J Krieglstein 2001 Neuroprotective effects of NV-31, a bilobalide-derived compound: Evidence for a antioxidative mechanism Brain Res 890 338-42 11164801 10.1016/S0006-8993(00)03202-9 1:CAS:528:DC%2BD3MXnsVCqtw%3D%3D
35. Y Luo 2001 Ginkgo biloba neuroprotection: Therapeutic implications in Alzheimer's disease J Alzheimers Dis 3 401-7 12214044 1:CAS:528:DC%2BD3MXnvF2lsbo%3D
36. Drieu K. Preparation and definition of Ginkgo biloba extract. In: Rokan (Ginkgo biloba). Recent results in pharmacology and clinic. Funfgeld EW (ed). Springer-Verlag, New York NY, 1988. p. 32-6
37. H Jaggy 1993 The active ingredients of the Ginkgo biloba extract EGb761 Haemostasiologie 13 7-10 1:CAS:528:DyaK3sXlvVygsLk%3D
38. J Meciano Filho VC Carvalho RR de Souza 1995 Nerve cell loss in the myenteric plexuz of the human esophagus in relation to age: A preliminary investigation Gerontology 41 1 18-21 7737530 1:STN:280:ByqB2MrmvVc%3D
39. AJA Barbosa 1973 Auerbach's plexus of the albino rat. I. Quantitative study of the ganglia and nerve cells in the caecum and colon. Pesqui Med Biol 6 253-62 1:STN:280:CSuD1cfmtlQ%3D
40. JL Dahl DD Bloom ML Epstein DA Fox P Bass 1987 Effect of chemical ablation of myenteric neurons on neurotransmitter levels in the rat jejunum Gastroenterology 92 338-44 3792770 1:CAS:528:DyaL2sXhtFCjsrY%3D
41. NC Buttow S Zucoloto EM Espreafico P Gama EP Alvares 2003 Substance P enhance neuronal area and epithelial cell proliferation after colon denervation in rats Dig Dis Sci 48 2069-76 14627357 10.1023/ A:1026103311800 1:CAS:528:DC%2BD3sXotFemtrs%3D
42. NC Buttow M Santin LC Macedo AC Neres Teixeira GC Novakowski TR Bolonheis Armelin 2004 Study of the myenteric and submucous plexuses after BAC treatment in the intestine of rats Biocell 28 135-42 15462564
43. OA Gomes RR Souza EA Liberti 1997 A preliminary investigation of the effects of aging on the nerve cell number in the myenteric ganglia of the human colon Gerontology 43 210-7 9222749 1:STN:280:ByiA28rpt1Y%3D