Pharmacokinetics and metabolism of an α,β-blocker, amosulalol hydrochloride, in mice: Biliary excretion of carbamoyl glucuronide

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 8, 2007, Pages 1580-1585

  Suzuki, Katsuhiro ^a   Kamimura, Hidetaka ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Amosulalol; Carbamoyl glucuronide; Metabolism; Mouse; Pharmacokinetics

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; AMOSULALOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARBAMOYL GLUCURONIDE; CARBON 14; DRUG METABOLITE; GLUCURONIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BILIARY EXCRETION; CONTROLLED STUDY; DRUG BILE LEVEL; DRUG HALF LIFE; DRUG METABOLISM; DRUG URINE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSTITUTE FOR CANCER RESEARCH MOUSE; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; RADIOACTIVITY; RAT; ULTRAVIOLET RADIATION;

ADRENERGIC ALPHA-ANTAGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; AREA UNDER CURVE; BILE; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ETHANOLAMINES; FECES; GLUCURONIDES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; MICE; MICE, INBRED ICR; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 34548016818     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.1580     Document Type: Article

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