Reductionist and system approaches to study the role of infection in preterm labor and delivery

BMC Pregnancy and Childbirth

Volumn 7, Issue SUPPL. 1, 2007, Pages

  Laudanski, Piotr ^a   Pierzynski, Piotr ^a   Laudanski, Tadeusz ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

AMNIOCENTESIS; BACTERIAL INFECTION; BODY FLUID; CHORIOAMNIONITIS; CONFERENCE PAPER; DELIVERY; FEMALE; GENE CLUSTER; HUMAN; HUMAN GENOME; MEDICAL RESEARCH; METHODOLOGY; METRITIS; PATHOGENESIS; PREMATURE LABOR; PROTEIN BLOOD LEVEL; PROTEOMICS; GYNECOLOGIC DISEASE; IMMUNOLOGY; MICROBIOLOGY; NEWBORN; PREGNANCY; PREGNANCY COMPLICATION; REVIEW;

BACTERIAL INFECTIONS; FEMALE; GENITAL DISEASES, FEMALE; HUMANS; INFANT, NEWBORN; OBSTETRIC LABOR, PREMATURE; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; RESEARCH DESIGN;

EID: 34548015426     PISSN: None     EISSN: 14712393     Source Type: Journal    
DOI: 10.1186/1471-2393-7-S1-S9     Document Type: Conference Paper

References (30)

1. Nesin M Genetic basis of preterm birth Front Biosci 2007, 12:115-124 10.2741/2052 17127287
2. Ananth CV Vintzileos AM Epidemiology of preterm birth and its clinical subtypes J Matern Fetal Neonatal Med 2006, 19:773-782 10.1080/ 14767050600965882 17190687
3. Al-Dabbagh SA Al-Taee WY Risk factors for pre-term birth in Iraq: A case-control study BMC Pregnancy Childbirth 2006, 6(13):1479367-16618372 10.1186/1471-2393-6-13
4. Institute of Medicine (IOM) Report on Preterm Birth 2006 http://www.iom.edu/CMS/3740/25471/35813.aspx
5. Romero R Espinoza J Goncalves LF Kusanovic JP Friel LA Nien JK Inflammation in preterm and term labour and delivery Semin Fetal Neonatal Med 2006, 11:317-326 10.1016/j.siny.2006.05.001 16839830
6. Goldenberg RL Hauth JC Andrews WW Intrauterine infection and preterm delivery N Engl J Med 2000, 342:1500-1507 10.1056/NEJM200005183422007 10816189
7. Pararas MV Skevaki CL Kafetzis DA Preterm birth due to maternal infection: Causative pathogens and modes of prevention Eur J Clin Microbiol Infect Dis 2006, 25:562-569 10.1007/s10096-006-0190-3 16953371
8. Bearfield C Davenport ES Sivapathasundaram V Allaker RP Possible association between amniotic fluid micro-organism infection and microflora in the mouth BJOG: Int J Obstet Gynaecol 2002, 109:527-533 10.1111/j.1471-0528.2002.01349.x
9. Wenstrom KD Andrews WW Hauth JC Goldenberg RL DuBard M Cliver S Elevated second-trimester amniotic fluid interleukin-6 levels predict preterm delivery Am J Obstet Gynecol 1998, 178:546-550 10.1016/ S0002-9378(98)70436-3 9539524
10. Horowitz S Mazor M Romero R Horowitz J Glezerman M Infection of the amniotic cavity with ureaplasma uralyticum in the midtrimester of pregnancy J Reprod Med 1995, 40:375-379 7608879
11. Keelan JA Coleman M Mitchell MD The molecular mechanisms of term and preterm labor: Recent progress and clinical implications Clin Obstet Gynecol 1997, 40:460-478 10.1097/00003081-199709000-00004 9328726
12. Hirsch E Wang H The molecular pathophysiology of bacterially induced preterm labor: Insights from the murine model J Soc Gynecol Investig 2005, 12:145-155 10.1016/j.jsgi.2005.01.007 15784499
13. Ahn AC Tewari M Poon CS Phillips RS The limits of reductionism in medicine: Could systems biology offer an alternative? PLoS Med 2006, 3:e208 1459480 16681415 10.1371/journal.pmed.0030208
14. Meis PJ Goldenberg RL Mercer B The preterm prediction study: Significace of vaginal infections Am J Obstet Gynecol 1995, 173:1231-1235 10.1016/ 0002-9378(95)91360-2 7485327
15. Goldenberg RL Goepfert AR Ramsey PS Biochemical markers for the prediction of preterm birth Am J Obstet Gynecol 2005, 192:S36-46 10.1016/ j.ajog.2005.02.015 15891711
16. Keelan JA Blumenstein M Helliwell RJ Sato TA Marvin KW Mitchell MD Cytokines, prostaglandins and parturition - a review Placenta 2003, 24(Suppl A):S33-46 10.1053/plac.2002.0948 12842412
17. Arntzen KJ Kjollesdal AM Halgunset J Vatten L Austgulen R IL-1, IL-6, IL-8 and soluble TNF receptors in relation to chrorioamnionitis and premature labor J Perinat Med 1998, 26:17-26 9595363
18. Genc MR Witkin SS Delaney ML A disproportionate increase in IL-1beta over IL-1ra in the cervicovaginal secretions of pregnant women with altered vaginal microflora correlates with preterm birth Am J Obstet Gynecol 2004, 190:1191-1197 15167817
19. Simhan HN Caritis SN Krohn MA de Tajada BM Landers DV Hillier SL Decreased cervical proinflammatory cytokines permit subsequent upper genital tract infection during pregnancy Am J Obstet Gynecol 2003, 189:560-567 10.1067/S0002-9378(03)00518-0 14520234
20. Ahn AC Tewari M Poon C-S Phillips RS The clinical applications of a systems approach PLoS Med 2006, 3:e209 1459481 16683861 10.1371/ journal.pmed.0030209
21. Laudanski P Lemancewicz A Pierzynski P Akerlund M Laudanski T Decreased serum level of macrophage inflammatory chemokine-3β/CCL19 in preterm labor and delivery Eur J Obstet Gynecol Reprod Biol 2006, 124:23-26 10.1016/j.ejogrb.2005.05.006 16023779
22. Gravett MG Novy MJ Rosenfeld RG Reddy AP Jacob T Turner M McCormack A Lapidus JA Hitti J Eschenbach DA Diagnosis of intra-amniotic infection by proteomic profiling and identification of novel biomarkers JAMA 2004, 292:462-469 10.1001/jama.292.4.462 15280344
23. Ruetschi U Rosen A Karlsson G Zetterberg H Rymo L Hagberg H Jacobsson B Proteomic analysis using protein chips to detect biomarkers in cervical and amniotic fluid in women with intra-amniotic inflammation J Proteome Res 2005, 4:2236-2242 10.1021/pr050139e 16335971
24. Buhimschi IA Buhimschi CS Weiner CP Kimura T Hamar BD Sfakianaki AK Norwitz ER Funai EF Ratner E Proteomic but not enzyme-linked immunosorbent assay technology detects amniotic fluid monomeric calgranulins from their complexed calprotectin form Clin Diagn Lab Immunol 2005, 12:837-844 1182206 16002632 10.1128/CDLI.12.7.837-844.2005
25. Buhimschi CS Weiner CP Buhimschi IA Proteomics, Part II: The emerging role of proteomics over genomics in spontaneous preterm labor/birth Obstet Gynecol Surv 2006, 61:543-553 10.1097/01.ogx.0000228779.39568.59 16842635
26. Charpigny G Leroy MJ Breuiller-Fouche M Tanfin Z Mhaouty-Kodja S Robin P Leiber D Cohen-Tannoudji J Cabrol D Barberis C Germain G A functional genomic study to identify differential gene expression in the preterm and term human myometrium Biol Reprod 2003, 68:2289-2296 10.1095/ biolreprod.102.013763 12606369
27. Breuiller-Fouche M Germain G Gene and protein expression in the myometrium in pregnancy and labor Reproduction 2006, 131:837-850 10.1530/ rep.1.00725 16672349
28. Marvin KW Keelan JA Eykholt RL Sato TA Mitchell MD Use of cDNA arrays to generate differential expression profiles for inflammatory genes in human gestational membranes delivered at term and preterm Mol Hum Reprod 2002, 8:399-408 10.1093/molehr/8.4.399 11912289
29. Tromp G Kuivaniemi H Romero R Chaiworapongsa T Kim YM Kim MR Maymon E Edwin S Genome-wide expression profiling of fetal membranes reveals a deficient expression of proteinase inhibitor 3 in premature rupture of membranes Am J Obstet Gynecol 2004, 191:1331-1338 10.1016/ j.ajog.2004.07.010 15507962
30. Khoury MJ Romero R The integration of genomics into obstetrics and gynecology: A HuGE challenge Am J Obstet Gynecol 2006, 195:1503-1505 10.1016/j.ajog.2006.10.883 17132472