Recovery of vision and pupil responses in optic neuritis and multiple sclerosis

Ophthalmic and Physiological Optics

Volumn 27, Issue 5, 2007, Pages 451-460

  Moro, S I ^a   Rodriguez Carmona, M L ^a   Frost, E C ^a   Plant, G T ^b,c   Barbur, J L ^a  

^a CITY UNIVERSITY   (United Kingdom)

^b NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^c MOORFIELDS EYE HOSPITAL   (United Kingdom)

Author keywords

Colour; Demyelination; Multiple sclerosis; Optic neuritis; Pupil

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; COLOR; COLOR VISION; CONTROLLED STUDY; CONVALESCENCE; DEMYELINATING DISEASE; DIAGNOSTIC PROCEDURE; FEMALE; HUMAN; LATENT PERIOD; LUMINANCE; MALE; MODULATION; MULTIPLE SCLEROSIS; OPTIC NEURITIS; PRIORITY JOURNAL; PUPIL; RELAPSE; REMISSION; VISION; VISUAL ACUITY; VISUAL FIELD; VISUAL STIMULATION;

ADULT; COLOR PERCEPTION; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; OPTIC NEURITIS; PHOTIC STIMULATION; PUPIL; RECOVERY OF FUNCTION; REFLEX, PUPILLARY; RETINA; TIME FACTORS; VISION TESTS; VISUAL ACUITY;

EID: 34548010749     PISSN: 02755408     EISSN: 14751313     Source Type: Journal    
DOI: 10.1111/j.1475-1313.2007.00501.x     Document Type: Article

References (54)

1. Alexandridis, E., Argyropoulos, T. Krastel, H. (1981) The latent period of the pupil light reflex in lesions of the optic nerve. Ophthalmologica 182, 211 217.
2. Alexandridis, E., Leendertz, J. A. Barbur, J. L. (1992) Methods of studying the behaviour of the pupil. J. Psychophysiol. 5, 223 239.
3. Audoin, B., Fernando, K. T., Swanton, J. K., Thompson, A. J., Plant, G. T. Miller, D. H. (2006) Selective magnetization transfer ratio decrease in the visual cortex following optic neuritis. Brain 129, 1031 1039.
4. Bailey, I. L. Lovie, J. E. (1976) New design principles for visual acuity letter charts. Am. J. Optom. Physiol. Opt. 53, 740 745.
5. Balcer, L. J. (2006) Clinical practice. Optic neuritis. N. Engl. J. Med. 354, 1273 1280.
6. Barbur, J. L. (2004a) 'Double-blindsight' revealed through the processing of color and luminance contrast defined motion signals. Prog. Brain Res. 144, 243 259.
7. Barbur, J. L. (2004b) Learning from the pupil - studies of basic mechanisms and clinical applications. In : The Visual Neurosciences (eds L. M. Chalupa J. S. Werner MIT Press, Cambridge, MA, pp. 641 656.
8. Barbur, J. L., Thomson, W. D. Forsyth, P. M. (1987) A new system for the simultaneous measurement of pupil size and two-dimensional eye-movements. Clin. Vis. Sci. 2, 131 142.
9. Barbur, J. L., Harlow, A. J. Sahraie, A. (1992) Pupillary responses to stimulus structure, color and movement. Ophthalmic Physiol. Opt. 12, 137 141.
10. Barbur, J. L., Harlow, A. J. Plant, G. T. (1994) Insights into the different exploits of color in the visual cortex. Proc. R. Soc. Lond., B, Biol. Sci. 258, 327 334.
11. Barbur, J. L., Harlow, A. J., Moro, S. Levy, I. S. (2000) Perimetric Study of Relative Afferent Pupil Defects. Non-invasive Assessment of the Visual System (Technical Digest Series), pp. 26 29. Optical Society of America, Washington, DC.
12. Barbur, J. L., Moro, S., Harlow, J. A., Lam, B. L. Liu, M. (2004) Comparison of pupil responses to luminance and colour in severe optic neuritis. Clin. Neurophysiol. 115, 2650 2658.
13. Beck, R. W. (1991) The clinical profile of optic neuritis - experience of the optic neuritis treatment trial. Arch. Ophthalmol. 109, 1673 1678.
14. Beck, R. W., Gal, R. L., Bhatti, M. T., Brodsky, M. C., Buckley, E. G., Chrousos, G. A., Corbett, J., Eggenberger, E., Goodwin, J. A., Katz, B., Kaufman, D. I., Keltner, J. L., Kupersmith, M. J., Miller, N. R., Moke, P. S., Nazarian, S., Orengo-Nania, S., Savino, P. J., Shults, W. T., Smith, C. H., Trobe, J. D., Wall, M. Xing, D. (2004) Visual function more than 10 years after optic neuritis: experience of the optic neuritis treatment trial. Am. J. Ophthalmol. 137, 77 83.
15. Bose, S., Dhillon, N., Ross-Cisneros, F. N. Carelli, V. (2005) Relative post-mortem sparing of afferent pupil fibers in a patient with 3460 Leber's hereditary optic neuropathy. Graefes Arch. Clin. Exp. Ophthalmol. 243, 1175 1179.
16. Bremner, F. D., Shallo-Hoffmann, J., Riordan-Eva, P. Smith, S. E. (1999) Comparing pupil function with visual function in patients with Leber's hereditary optic neuropathy. Invest. Ophthalmol. Vis. Sci. 40, 2528 2534.
17. Brusa, A., Jones, S. J., Kapoor, R., Miller, D. H. Plant, G. T. (1999) Long-term recovery and fellow eye deterioration after optic neuritis, determined by serial visual evoked potentials. J. Neurol. 246, 776 782.
18. Brusa, A., Jones, S. J. Plant, G. T. (2001) Long-term remyelination after optic neuritis: a 2-year visual evoked potential and psychophysical serial study. Brain 124, 468 479.
19. Calkins, D. J. (1999) Synaptic organization of cone pathways in the primate retina. In : Color Vision. From Genes to Perception (eds K. R. Gegenfurtner L. S. Sharpe Cambridge University Press, Cambridge, pp. 163 179.
20. Costello, F., Coupland, S., Hodge, W., Lorello, G. R., Koroluk, J., Pan, Y. I., Freedman, M. S., Zackon, D. H. Kardon, R. H. (2006) Quantifying axonal loss after optic neuritis with optical coherence tomography. Ann. Neurol. 59, 963 969.
21. Cox, T. A. (1989) Relative afferent pupillary defects in multiple sclerosis. Can. J. Ophthalmol. 24, 207 210.
22. Dacey, D. M. (1996) Circuitry for color coding in the primate retina. Proc. Natl Acad. Sci. USA 93, 582 588.
23. Dalton, C. M., Brex, P. A., Miszkiel, K. A., Hickman, S. J., MacManus, D. G., Plant, G. T., Thompson, A. J. Miller, D. H. (2002) Application of the new McDonald criteria to patients with clinically isolated syndromes suggestive of multiple sclerosis. Ann. Neurol. 52, 47 53.
24. Druschky, A., Heckmann, J. G., Claus, D., Katalinic, A., Druschky, K. F. Neundorfer, B. (1999) Progression of optic neuritis to multiple sclerosis: an 8-year follow-up study. Clin. Neurol. Neurosurg. 101, 189 192.
25. Ellis, C. J. (1979) The afferent pupillary defect in acute optic neuritis. J. Neurol. Neurosurg. Psychiatry 42, 1008 1017.
26. Evangelou, N., Konz, D., Esiri, M. M., Smith, S., Palace, J. Matthews, P. M. (2001) Size-selective neuronal changes in the anterior optic pathways suggest a differential susceptibility to injury in multiple sclerosis. Brain 124, 1813 1820.
27. Fison, P. N., Garlick, D. J. Smith, S. E. (1979) Assessment of unilateral afferent pupillary defects by pupillography. Br. J. Ophthalmol. 63, 195 199.
28. Fitzgibbon, A. W., Pilu, M. Fisher, R. B. (1999) Direct least-squares fitting of ellipses. IEEE Trans. Pattern Anal. Mach. Intell. 21, 476 480.
29. Flanagan, P. Markulev, C. (2005) Spatio-temporal selectivity of loss of colour and luminance contrast sensitivity with multiple sclerosis and optic neuritis. Ophthalmic Physiol. Opt. 25, 57 65.
30. Flanagan, P. Zele, A. J. (2004) Chromatic and luminance losses with multiple sclerosis and optic neuritis measured using dynamic random luminance contrast noise. Ophthalmic Physiol. Opt. 24, 225 233.
31. Fleishman, J. A., Beck, R. W., Linares, O. A. Kelen, J. W. (1987) Deficits in visual function after resolution of optic neuritis. Ophthalmology 94, 1029 1033.
32. Haley, M. J. (1987) Interpreting Test Results with Statpac. The Field Analyzer Primer, pp. 133 134. Allergan Humphrey, San Leandro, CA.
33. Hess, R. F. Plant, G. T. (1986) Optic Neuritis. Cambridge University Press, Cambridge.
34. Hickman, S., Dalton, C., Miller, D. H. Plant, G. T. (2002) Management of acute optic neuritis. Lancet 360, 1953 1962.
35. Hickman, S. J., Toosy, A. T., Miszkiel, K. A., Jones, S. J., Altmann, D. R., MacManus, D. G., Plant, G. T., Thompson, A. J. Miller, D. H. (2004) Visual recovery following acute optic neuritis - a clinical, electrophysiological and magnetic resonance imaging study. J. Neurol. 251, 996 1005.
36. Howell, D. C. (2002) Statistical Methods for Psychology, 5th edn. Duxbury Press, Belmont, CA.
37. Kaplan, E. Shapley, R. (1986) The primate retina contains two types of ganglion cells, with high and low contrast sensitivity. Proc. Natl Acad. Sci. USA 83, 2755 2757.
38. Kardon, R. H. (1995) Pupillary light reflex. Curr. Opin. Ophthalmol. 6, 20 26.
39. Kardon, R. H., Haupert, C. L. Thompson, H. S. (1993) The relationship between static perimetry and the relative afferent pupillary defect. Am. J. Ophthalmol. 115, 351 356.
40. Kidd, D., Burton, B. J. L., Plant, G. T. Graham, E. M. (2003) Chronic relapsing inflammatory optic neuropathy (CRION). Brain 126, 276 284.
41. Levine, M. W. (2000) Fundamentals of Sensation and Perception. Oxford University Press, Oxford.
42. Mullen, K. T. Plant, G. T. (1986) Colour and luminance vision in human optic neuritis. Brain 109, 1 13.
43. Murray, P. D., McGavern, D. B., Sathornsumetee, S. Rodriguez, M. (2001) Spontaneous remyelination following extensive demyelination is associated with improved neurological function in a viral model of multiple sclerosis. Brain 124, 1403 1416.
44. Optic Neuritis Study Group 1997) The 5-year risk of MS after optic neuritis - experience of the optic neuritis treatment trial. Neurology 49, 1404 1413.
45. Perry, V. H. Cowey, A. (1984) Retinal ganglion cells that project to the superior colliculus and pretectum in the macaque monkey. Neuroscience 12, 1125 1137.
46. Pozzessere, G., Rossi, P., Valle, E., Froio, C. P., Petrucci, A. F. G. Morocutti, C. (1997) Autonomic involvement in multiple sclerosis: a pupillometric study. Clin. Auton. Res. 7, 315 319.
47. Russell, M. H., Murray, I. J., Metcalfe, R. A. Kulikowski, J. J. (1991) The visual defect in multiple sclerosis and optic neuritis. A combined psychophysical and electrophysiological investigation. Brain 114, 2419 2435.
48. Sartucci, F., Murri, L., Orsini, C. Porciatti, V. (2001) Equiluminant red-green and blue-yellow VEPs in multiple sclerosis. J. Clin. Neurophysiol. 18, 583 591.
49. Schneck, M. E. Haegerstrom-Portnoy, G. (1997) Color vision defect type and spatial vision in the optic neuritis treatment trial. Invest. Ophthalmol. Vis. Sci. 38, 2278 2289.
50. Shapley, R. (1990) Visual sensitivity and parallel retino-cortical channels. Annu. Rev. Psychol. 41, 635 658.
51. Trapp, B. D., Peterson, J., Ransohoff, R. M., Rudick, R., Mork, S. Bo, L. (1998) Axonal transection in the lesions of multiple sclerosis. N. Engl. J. Med. 338, 278 285.
52. Trip, S. A., Schlottmann, P. G., Jones, S. J., Altmann, D. R., Garway-Heath, D. F., Thompson, A. J., Plant, G. T. Miller, D. H. (2005) Retinal nerve fiber layer axonal loss and visual dysfunction in optic neuritis. Ann. Neurol. 58, 383 391.
53. Wyszecki, G. Stiles, W. S. (1982) Color Science - Concepts and Methods, Quantitative Data and Formulae, 2nd edn. John Wiley & Sons, New York, USA.
54. Young, R. S. Teller, D. Y. (1991) Determination of lights that are isoluminant for both scotopic and photopic vision. J. Opt. Soc. Am. A 8, 2048 2052.