Enantioselective analysis of the antipsychotic 9-hydroxyrisperidone, main metabolite of risperidone, by chiral capillary EKC using dual CDs

Electrophoresis

Volumn 28, Issue 15, 2007, Pages 2683-2692

  Danel, Cécile ^a   Chaminade, Pierre ^b   Odou, Pascal ^a   Bartélémy, Christine ^a   Azarzar, Dalila ^a   Bonte, Jean Paul ^a   Vaccher, Claude ^a  

^a UNIV LILLE   (France)

^b University Paris Saclay   (France)

Author keywords

9 Hydroxyrisperidone; Central composite design; Chiral capillary EKC; Dual CD mode; Highly sulfated cyclodextrins

Indexed keywords

ENANTIOMERS;

9-HYDROXYRISPERIDONE; ANALYTICAL METHOD; CENTRAL COMPOSITE DESIGNS; CHIRAL CAPILLARY EKC; DUAL CD MODE; ENANTIOSELECTIVE ANALYSIS; ENANTIOSEPARATIONS; HIGHLY SULPHATED CYCLODEXTRIN; RISPERIDONE; SULFATED CYCLODEXTRINS;

METABOLITES;

ALPHA CYCLODEXTRIN; BETA CYCLODEXTRIN; CYCLODEXTRIN DERIVATIVE; GAMMA CYCLODEXTRIN; NEUROLEPTIC AGENT; PALIPERIDONE; RISPERIDONE;

ARTICLE; CHIRALITY; CONTROLLED STUDY; DRUG STRUCTURE; ENANTIOMER; ENANTIOSELECTIVITY; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; PH; RESPONSE SURFACE METHOD; SEPARATION TECHNIQUE; TEMPERATURE; UNIVARIATE ANALYSIS;

BETA-CYCLODEXTRINS; CHROMATOGRAPHY, MICELLAR ELECTROKINETIC CAPILLARY; ISOXAZOLES; PYRIMIDINES; RISPERIDONE; STEREOISOMERISM;

EID: 34547911395     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200600837     Document Type: Article

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