Angiotensin receptor blockade and angiotensin-converting-enzyme inhibition limit adverse remodeling of infarct zone collagens and global diastolic dysfunction during healing after reperfused ST-elevation myocardial infarction

Molecular and Cellular Biochemistry

Volumn 303, Issue 1-2, 2007, Pages 27-38

  Jugdutt, Bodh I ^a   Idikio, Halliday ^a   Uwiera, Richard R E ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Angiotensin II inhibition; Collagen; Diastolic function; Remodeling; Reperfusion; ST elevation myocardial infarction

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; CANDESARTAN; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; PLACEBO; PYRIDINOLINE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DIASTOLE; DIASTOLIC DYSFUNCTION; DOG; HEALING; HEART HEMODYNAMICS; HEART INFARCTION; HEART LEFT VENTRICLE FILLING PRESSURE; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE SIZE; HEART MUSCLE REPERFUSION; HEART VENTRICLE REMODELING; ISOLATED HEART; NONHUMAN; ST SEGMENT ELEVATION; SURVIVAL; SYSTOLE; TREATMENT OUTCOME;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; BENZIMIDAZOLES; COLLAGEN; DOGS; ENALAPRIL; HYDROXYPROLINE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION; PEPTIDYL-DIPEPTIDASE A; RECEPTORS, ANGIOTENSIN; TETRAZOLES; TRANSFORMING GROWTH FACTOR BETA1; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING; WOUND HEALING;

CANIS FAMILIARIS;

EID: 34547908502     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-007-9452-3     Document Type: Article

References (38)

1. Kloner RA, Ellis SG, Lange R et al (1983) Studies of experimental coronary artery reperfusion: Effects on infarct size, myocardial function, biochemistry, ultrastructure and microvascular damage. Circulation 68(suppl I):I8-15
2. Murakami T, Kusachi S, Murakami M et al (1998) Time-dependent changes of serum carboxy-terminal peptide of type I procollagen and carboxy-terminal telopeptide of type I collagen concentrations in patients with acute myocardial infarction after successful reperfusion: correlation with left ventricular volume indices. Clin Chem 44:2453-2461
3. Frangogiannis NG, Mendoza LH, Lindsey ML et al (2000) IL-10 is induced in the reperfused myocardium and may modulate the reaction to injury. J Immunol 165:2798-2808
4. Jugdutt BI (1997) Effect of reperfusion on ventricular mass, topography and function during healing of anterior infarction. Am J Physiol 272:H1205-H1211
5. Zhao MJ, Zhang H, Robinson TF et al (1987) Profound structural alterations of the extracellular collagen matrix in postischemic dysfunctional ("stunned") but viable myocardium. J Am Coll Cardiol 10:1322-1334
6. 1 receptor blockade. J Card Fail 10:442-449
7. Connelly CM, Vogel WM, Wiegner AW et al (1985) Effects of reperfusion after coronary artery occlusion on post-infarction scar tissue. Circ Res 57:562-577
8. Boyle MP, Weisman HF (1993) Limitation of infarct expansion and ventricular remodeling by late reperfusion. Study of time course and mechanism in a rat model. Circulation 88:2872-2883
9. Bolognese L, Neskovic AN, Parodi G et al (2002) Left ventricular remodeling after primary coronary angioplasty: Patterns of left ventricular dilation and long-term prognostic implications. Circulation 106:2351-2357
10. The SOLVD Investigators (1991) Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med 325:293-302
11. Pfeffer MA, Swedberg K, Granger CB et al; CHARM Investigators and Committees (2003) Effects of candesartan on mortality and morbidity in patients with chronic heart failure: The CHARM-Overall programme. Lancet 362:759-766
12. Pfeffer MA, Braunwald E, Moye LA et al (1992) Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. The SAVE Investigators. N Engl J Med 327:669-677
13. St John Sutton M, Pfeffer MA, Plappert T et al for the SAVE Investigators (1994) Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective effects of captopril. Circulation 89:68-75
14. Pfeffer MA, McMurray JJ, Velazquez EJ et al;Valsartan in Acute Myocardial Infarction Trial Investigators (2003) Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med 349:1893-1906
15. Solomon SD, Skali H, Anavekar NS et al (2005) Changes in ventricular size and function in patients treated with valsartan, captopril, or both after myocardial infarction. Circulation 111:3411-3419
16. Jugdutt BI, Lucas A, Khan MI (1997) Effect of ACE inhibition on infarct collagen deposition and remodeling during healing after transmural canine myocardial infarction. Can J Cardiol 13:657-668
17. van Krimpen C, Schoemaker RG, Cleutjens JP et al (1991) Angiotensin I converting enzyme inhibitors and cardiac remodeling. Basic Res Cardiol 86:149-155
18. Jugdutt BI (2003) Ventricular remodeling postinfarction and the extracellular collagen matrix. When is enough enough? Circulation 108:1395-1403
19. Smits JF, van Krimpen C, Schoemaker RG et al (1992) Angiotensin II receptor blockade after myocardial infarction in rats: Effects on hemodynamics, myocardial DNA synthesis, and interstitial collagen content. J Cardiovasc Pharmacol 20:772-778
20. Schoemaker RG, Debets JJ, Struyker-Boudier HA et al (1991) Delayed but not immediate captopril therapy improves cardiac function in conscious rats, following myocardial infarction. J Mol Cell Cardiol 23:187-197
21. Diez J, Querejeta R, Lopez B et al (2002) Losartan-dependent regression of myocardial fibrosis is associated with reduction of left ventricular chamber stiffness in hypertensive patients. Circulation 105:2512-2517
22. 1 receptor blocker added to ACE inhibitor provides benefits at advanced stage of hypertensive diastolic heart failure. Hypertension 43:686-691
23. Jugdutt BI, Menon V, D. Kumar et al (2002) Vascular remodeling during healing after reperfused myocardial infarction in the dog model. Effects of reperfusion, amlodipine and enalapril. J Am Coll Cardiol 39:1538-1545
24. Jugdutt BI, Xu Y, Balghith M et al (2001) Cardioprotective effects of angiotensin II type 1 receptor blockade with candesartan after reperfused myocardial infarction: Role of angiotensin II type 2 receptor. JRAAS 2:S162-S166
25. Jugdutt BI, Khan MI, Jugdutt SJ et al (1995) Effect of enalapril on ventricular remodeling and function during healing after anterior myocardial infarction in the dog. Circulation 91:802-812
26. Jugdutt BI (1997) Effect of amlodipine versus enalapril on left ventricular remodeling after anterior reperfused myocardial infarction. Can J Cardiol 13:945-954
27. Jugdutt BI, Joljart MJ, Khan MI (1996) Rate of collagen deposition during healing after myocardial infarction in the rat and dog models: mechanistic insights into ventricular remodeling. Circulation 94:94-101
28. Klotz S, Foronjy RF, Dickstein ML et al (2005) Mechanical unloading during left ventricular assist device support increases left ventricular collagen cross-linking and myocardial stiffness. Circulation 112:364-374
29. Miller EJ, Rhodes RK (1982) Preparation and characterization of the different types of collagen. Method Enzymol 82(Pt A):33-64
30. Stegemann H, Stalder K (1967) Determination of hydroxyproline. Clin Chim Acta 18:267-273
31. Laurent GJ, Cockerill P, McAnulty RJ et al (1981) A simplified method for quantitation of the relative amounts of type I and type III collagen in small tissue samples. Anal Biochem 113:301-312
32. Cleutjens JP, Verluyten MJ, Smits JF et al (1995) Collagen remodeling after myocardial infarction in the rat heart. Am J Pathol 147:325-338
33. Sekita S, Katagiri T, Sasai Y et al (1985) Studies on collagen in the experimental myocardial infarction. Jpn Circ J 49:171-178
34. Whittaker P, Boughner DR, Kloner RA (1989) Analysis of healing after myocardial infarction using polarized light microscopy. Am J Pathol 134:879-893
35. Yu CM, Tipoe GL, Wing-Hon Lai K et al (2001) Effects of combination of angiotensin-converting enzyme inhibitor and angiotensin receptor antagonist on inflammatory cellular infiltration and myocardial interstitial fibrosis after acute myocardial infarction. J Am Coll Cardiol 38:1207-1215
36. Sun Y, Zhang JQ, Zhang J et al (1998) Angiotensin II, transforming growth factor-beta1 and repair in the infarcted heart. J Mol Cell Cardiol 30:1559-1569
37. Eghbali M, Tomek R, Sukhatme VP et al (1991) Differential effects of transforming growth factor-beta 1 and phorbol myristate acetate on cardiac fibroblasts. Regulation of fibrillar collagen mRNAs and expression of early transcription factors. Circ Res 69:483-490
38. Balghith M, Jugdutt BI (2002) Assessment of diastolic dysfunction after acute myocardial infarction using Doppler Echocardiography. Can J Cardiol 18:69-77