High fructose diet increases anterior hypothalamic alpha 2-adrenoceptors responsiveness

Neuroscience Letters

Volumn 423, Issue 2, 2007, Pages 128-132

  Mayer, Marcos A ^a   Höcht, Christian ^a   Opezzo, Javier A ^a   Taira, Carlos A ^a   Fernández, Belisario E ^a   Puyó, Ana M ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

2 Adrenoceptors; Fructose; Hypertension; Hypothalamus; Microdialysis; Noradrenaline

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE; NORADRENALIN; POSTSYNAPTIC RECEPTOR; PRESYNAPTIC RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTERIOR HYPOTHALAMUS; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; DRUG EFFECT; HEART RATE; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; MICRODIALYSIS; NERVE ENDING; NONHUMAN; PRIORITY JOURNAL; RAT; SYSTOLIC BLOOD PRESSURE;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; BLOOD PRESSURE; CLONIDINE; DIET; FRUCTOSE; HYPERTENSION; HYPOTHALAMUS, ANTERIOR; INSULIN RESISTANCE; MALE; MICRODIALYSIS; NOREPINEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2;

EID: 34547907767     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.06.046     Document Type: Article

References (39)

1. Alberti K.G.M.M., Zimmet P., and Shaw J. Metabolic syndrome-a new world-wide definition. A Consensus Statement from the International Diabetes Federation. Diabetes Med. 23 (2006) 469-480
2. Bealer S.L., and Abell S.O. Paraventricular nucleus histamine increases blood pressure by adrenoreceptor stimulation of vasopressin release. Am. J. Physiol. 269 (1995) H80-H85
3. Beverly J.L., de Vries M.G., Beverly M.F., and Arseneau L.M. Norepinephrine mediates glucoprivic-induced increase in GABA in the ventromedial hypothalamus of rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 279 (2000) R990-R996
4. Bock C., Niederhoffer N., and Szabo B. Analysis of the receptor involved in the central hypotensive effect of rilmenidine and moxonidine. Naunyn-Schmiedeberg's Arch. Pharmacol. 359 (1999) 262-271
5. Bourne J.A. Intracerebral microdialysis: 30 years as a tool for the neuroscientist. Clin. Exp. Pharmacol. Physiol. 30 (2003) 16-24
6. Buxton I.L.O. Pharmacokinetics and pharmacodynamics: the dynamics of drug absorption, distribution, action, and elimination. In: Brunton L.L., Lazo J.S., and Parker K.L. (Eds). Goodman & Gilman's the pharmacological basis of therapeutics (2006), Mc Graw Hill, New York 1-39
7. Chafetz M.D., Parko K., Diaz S., and Leibowitz S.F. Relationships between medial hypothalamic alpha 2-receptor binding, norepinephrine, and circulating glucose. Brain Res. 384 (1986) 404-408
8. Claassen V. Anaesthesia. Neglected factors in pharmacology and neuroscience research (1994), Elsevier, Amsterdam 382-421
9. Damiano P.F., Cavallero S., Mayer M.A., Rosón M.I., de la Riva I.J., Fernández B.E., and Puyó A.M. Impaired response to insulin associated to protein kinase C in chronic fructose-induced hypertension. Blood Press. 11 (2002) 345-351
10. de Wardener H.E. The hypothalamus and hypertension. Physiol. Rev. 81 (2001) 1599-1658
11. Folkow B., Johansson B., and Oberg B. A hypothalamic structure with a marked inhibitory effect on tonic sympathetic activity. Acta Physiol. Scand. 47 (1995) 262-270
12. Grassi G., Dell'Oro R., Facchini A., Quarti Trevano F., Bolla G.B., and Mancia G. Effect of central and peripheral body fat distribution on sympathetic and baroreflex function in obese normotensive. J. Hypertens. 22 (2004) 2363-2369
13. Grassi G., and Seravalle G. Autonomic imbalance and metabolic syndrome: unravelling interactions, mechanisms and outcomes. J. Hypertens. 24 (2006) 47-49
14. Hicks P.E. Central cardiovascular actions of histamine in rats: involvement of histamine H2-receptors. Clin. Exp. Hypertens. 1 (1978) 251-265
15. Höcht C., Lazarowski A., Gonzalez N.N., Auzmendi J., Opezzo J.A.W., Bramuglia G.F., Taira C.A., and Girardi E. Nimodipine restores the altered hippocampal phenytoin pharmacokinetics in a refractory epileptic model. Neurosci. Lett. 413 (2007) 168-172
16. Höcht C., Opezzo J.A.W., Gironacci M.M., Peña C., and Taira C.A. Anterior hypothalamic β-adrenoceptors in chronic aortic coarctated hypertensive rats. An interaction with central angiotensin II receptors. Clin. Exp. Pharmacol. Physiol. 32 (2005) 30-34
17. Hwang I.S., Ho H., Hoffmann B., and Reaven G.M. Fructose-induced insulin resistance and hypertension in rats. Hypertension 10 (1987) 512-516
18. Jhanwar-Uniyal M., Papamichael M.J., and Leibowitz S.F. Glucose-dependent changes in alpha 2-noradrenergic receptors in hypothalamic nuclei. Physiol. Behav. 44 (1988) 611-617
19. Kamide K., Rakugi H., Higaki J., Okamura A., Nagai M., Moriguchi K., Ohishi M., Satoh N., Tuck M., and Ogihara T. The renin-angiotensin and adrenergic nervous system in cardiac hypertrophy in fructose-fed rats. Am. J. Hypertens. 15 (2002) 66-71
20. Kubo T., Goshima Y., Ueda H., and Misu Y. Diminished alpha 2-adrenoceptor-mediated modulation of noradrenergic neurotransmission in the posterior hypothalamus of spontaneously hypertensive rats. Neurosci. Lett. 65 (1986) 29-34
21. Landsberg L. Insulin-mediated sympathetic stimulation: role in the pathogenesis of obesity-related hypertension (or, how insulin affects blood pressure and why). J. Hypertens. 19 (2001) 523-528
22. 2A-adrenergic receptor subtype. Science 273 (1996) 801-803
23. Martire M., Pistritto G., Mores N., Agnati L.F., and Fuxe K. Presynaptic α2-adrenoceptors and neuropeptide Y Y2 receptors inhibit [3H]noradrenaline release from rat hypothalamic synaptosomes via different mechanisms. Neurosci. Lett. 188 (1995) 9-12
24. Mayer M.A., Höcht C., Opezzo J.A.W., Peredo H.A., Navacchia D., Taira C.A., Fernandez B.E., and Puyó A. Role of hypothalamic alpha-2 adrenergic activity in fructose induced hypertension. Clin. Exp. Pharmacol. Physiol. 33 (2006) 904-909
25. McCulloch M.W., Medgett I.C., Rand M.J., and Story D.F. Structure-activity relationship of imidazoline derivates related to clonidine at histamine H2-receptrs in guinea-pig isolated atria. Br. J. Pharmacol. 69 (1980) 397-405
26. Oparil S., Chen Y.F., Meng Q.C., Yang R.H., Jin H.K., and Wyss J.M. The neural basis of salt sensitivity in the rat: altered hypothalamic function. Am. J. Med. Sci. 295 (1988) 360-369
27. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. second ed. (1986), Academic Press, New York
28. Pitts D.K., Beuthin F.C., and Commissaris R.L. Cardiovascular effects of perfusion of the rostral rat hypothalamus with clonidine: differential interactions with prazosin and yohimbine. Eur. J. Pharmacol. 124 (1986) 67-74
29. Saavedra J.M., Grobecker H., and Axelrod J. Changes in central catecholaminergic neurons in the spontaneously (genetic) hypertensive rat. Circ. Res. 42 (1978) 529-534
30. Sastre-Coll A., Esteban S., and Garcia-Sevilla J.A. Effects of imidazoline receptor ligands on monoamine synthesis in the rat brain in vivo. Naunyn-Schmiedeberg's Arch. Pharmacol. 360 (1999) 50-62
31. Sastre-Coll A., Esteban S., and García-Sevilla J.A. Supersensitivity of 5-HT1A-autoreceptors and α2-adrenoceptors regulating monoamine synthesis in the brain of morphine-dependent rats. Naunyn-Schmiedeberg's Arch. Pharmacol. 365 (2002) 210-219
32. Schlaich M.P., Lambert E., Kaye D.M., Krozowski Z., Campbell D.J., Lambert G., Hastings J., Aggarwal A., and Esler M.D. Sympathetic augmentation in hypertension. Role of nerve firing, norepinephrine reuptake, and angiotensin neuromodulation. Hypertension 43 (2004) 169-175
33. Szmigielska H., Szmigielski A., and Szadowska A. The sensitivity of alpha-adrenoceptors in nucleus tractus solitarii, anterior hypothalamus and hippocampus of spontaneous and renal hypertensive rats. Pol. J. Pharmacol. Pharm. 41 (1989) 413-419
34. Timm J., Marr I., Werthwein S., Elz S., Schunack W., and Schlicker E. H2 receptor-mediated facilitation and H3 receptor-mediated inhibition of noradrenaline release in the guinea-pig brain. Naunyn Schmiedeberg's Arch. Pharmacol. 357 (1998) 232-239
35. Ugedo L., Garro M.A., Pineda J., Giralt M.T., Miralles A., Olmos G., García-Sevilla J.A., Menargues A., and Obach R. Acute and chronic effects of reserpine on biochemical and functional parameters of central and peripheral alpha 2-adrenoceptors. Eur. J. Pharmacol. 239 1-3 (1993) 149-157
36. Verma S., Bhanot S., and McNeill J.H. Sympathectomy prevents fructose induced hyperinsulinemia and hypertension. Eur. J. Pharmacol. 373 (1999) R1-R4
37. Westerink B.H.C., and Vries J.B. A method to evaluate the diffusion rate of drugs from a microdialysis probe through brain tissue. J. Neurosci. Methods 109 (2001) 53-58
38. Westfall T.C., and Westfall D.P. Adrenergic agonists and antagonists. In: Brunton L.L., Lazo J.S., and Parker K.L. (Eds). Goodman & Gilman's The Pharmacological Basis of Therapeutics (2006), McGraw Hill, New York 237-295
39. Wyss J.M., Yang R.H., Jin H.K., and Oparil S. Hypothalamic microinjection of alpha 2-adrenoceptor agonists causes greater sympathoinhibition in spontaneously hypertensive rats on high NaCl diets. J. Hypertens. 6 (1988) 805-813