Sequential quadruple immunosuppression including sirolimus in extended criteria and nonheartbeating donor kidney transplantation

Transplantation

Volumn 84, Issue 3, 2007, Pages 429-432

  Diekmann, Fritz ^a   Campistol, Josep M ^a   Saval, Núria ^a   Gutiérrez Dalmau, Alex ^a   Arellano, Edgar M ^a   Crespo, Marta ^a   Rossich, Esther ^a   Esforzado, Núria ^a   Cofán, Federico ^a   Ricart, María José ^a   Torregrosa, José Vicente ^a   Oppenheimer, Federico ^a  

^a HOSPITAL CLÍNIC   (Spain)

Author keywords

Calcineurin inhibitor; Extended criteria donors; Interleukin 2 receptor antagonist; mTOR inhibitor; Mycophenolate mofetil; Nonheartbeating donors; Proteinuria; Rapamycin; Sirolimus; Thymoglobulin

Indexed keywords

BASILIXIMAB; CALCINEURIN INHIBITOR; GANCICLOVIR; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; RAPAMYCIN; THYMOCYTE ANTIBODY;

ABSCESS; ACUTE GRAFT REJECTION; ACUTE KIDNEY FAILURE; ADULT; AGED; ARTICLE; CREATININE CLEARANCE; DRUG SAFETY; EDEMA; FEMALE; GRAFT SURVIVAL; HIGH RISK PATIENT; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY DISEASE; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LYMPHOCELE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEINURIA; SEROMA; THROMBOTIC THROMBOCYTOPENIC PURPURA; URINARY TRACT FISTULA; WOUND HEALING IMPAIRMENT;

ADULT; AGED; ANTIBODIES, MONOCLONAL; CALCINEURIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; FEMALE; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; LIVING DONORS; MALE; MIDDLE AGED; MYCOPHENOLIC ACID; PILOT PROJECTS; PREDNISONE; RECOMBINANT FUSION PROTEINS; RISK FACTORS; SIROLIMUS;

EID: 34547901765     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000269610.13590.52     Document Type: Article

References (20)

1. Cohen B, D'Amaro J, De Meester J, Persijn GG. Changing patterns in organ donation in Eurotransplant, 1990 -94. Transpl Int 1997; 10: 1.
2. Lewis DM, Gorrie M, Bingham C, et al. Elderly donors in renal transplantation: a worthwhile venture? Transplant Proc 1998; 30: 2279.
3. Young JB. Age before beauty: the use of 'older' donor hearts for cardiac transplantation. J Heart Lung Transplant 1999; 18: 488.
4. Rosengard BR, Feng S, Alfrey EJ, et al. Report of the Crystal City meeting to maximize the use of organs recovered from the cadaver donor. Am J Transplant 2002; 2: 701.
5. Lee CM, Carter JT, Randall HB, et al. The effect of age and prolonged cold ischemia times on the national allocation of cadaveric renal allografts. J Surg Res 2000; 91: 83.
6. Johnston TD, Thacker LR, Jeon H, et al. Sensitivity of expanded-criteria donor kidneys to cold ischaemia time. Clin Transplant 2004; 18(Suppl 12): 28.
7. Scolari MP, Cappuccilli ML, Lanci N, et al. Predictive factors in chronic allograft nephropathy. Transplant Proc 2005; 37: 2482.
8. Groth CG, Backman L, Morales JM, et al. Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group. Transplantation 1999; 67: 1036.
9. Valente JF, Hricik D, Weigel K, et al. Comparison of sirolimus vs. mycophenolate mofetil on surgical complications and wound healing in adult kidney transplantation. Am J Transplant 2003; 3: 1128.
10. Langer RM, Kahan BD. Incidence, therapy, and consequences of lymphocele after sirolimus-cyclosporine-prednisone immunosuppression in renal transplant recipients. Transplantation 2002; 74: 804.
11. Pascual M, Swinford RD, Ingelfinger JR, et al. Chronic rejection and chronic cyclosporin toxicity in renal allografts. Immunol Today 1998; 19: 514.
12. Halloran PF, Melk A, Barth C. Rethinking chronic allograft nephropathy: the concept of accelerated senescence. J Am Soc Nephrol 1999; 10: 167.
13. Smits JM, Persijn GG, van Houwelingen HC, et al. Evaluation of the Eurotransplant Senior Program. The results of the first year. Am J Transplant 2002; 2: 664.
14. Meier-Kriesche H, Kaplan B. Renal transplantation: A half century of success and the long road ahead. J Am Soc Nephrol 2004; 15: 3270.
15. Fukuhara N, Ono Y, Hattori R, et al. The long-term outcome of tacrolimus in cadaveric kidney transplantation from non-heart beating donors. Clin Transplant 2005; 19: 153.
16. Sanchez-Fructuoso AI, Marques M, Prats D, et al. Victims of cardiac arrest occurring outside the hospital: a source of transplantable kidneys. Ann In Med 2006; 145: 157.
17. Renkens JJ, Rouflart MM, Christiaans MH, et al. Outcome of nonheart-beating donor kidneys with prolonged delayed graft function after transplantation. Am J Transplant 2005; 5: 2704.
18. Wilson CH, Brook NR, Gok MA, et al. Prospective randomised trial of the use of Daclizumab in renal transplantation using kidneys from non heart beating donors. Ann Transplant 2004; 9: 29.
19. Dean PG, Lund WJ, Larson TS, et al. Wound-healing complications after kidney transplantation: A prospective, randomized comparison of sirolimus and tacrolimus. Transplantation 2004; 10: 1555.
20. Kahan BD for the Rapamune US Study Group. Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection. A randomized multicentre study. Lancet 2000; 356: 194.