Rapid-onset type 1 diabetes associated with cytomegalovirus infection and islet autoantibody synthesis

Internal Medicine

Volumn 46, Issue 12, 2007, Pages 873-877

  Osame, Keiichiro ^a   Takahashi, Yoshihiko ^a   Takasawa, Hirofumi ^a   Watanabe, Shigeru ^b   Kishimoto, Miyako ^a   Yasuda, Kazuki ^a   Kaburagi, Yasushi ^a   Nakanishi, Koji ^b   Kajio, Hiroshi ^a   Noda, Mitsuhiko ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b TORANOMON HOSPITAL   (Japan)

Author keywords

Cytomegalovirus; Diabetes; GAD65; Ketoacidosis

Indexed keywords

AMYLASE; AUTOANTIBODY; C REACTIVE PROTEIN; FOSCARNET; GANCICLOVIR; GLUTAMATE DECARBOXYLASE 65 ANTIBODY; GLUTAMATE DECARBOXYLASE ANTIBODY; HEMOGLOBIN; HEMOGLOBIN A1C; HLA A24 ANTIGEN; HLA DR ANTIGEN; IMMUNOGLOBULIN G ANTIBODY; INSULIN; INSULIN GLARGINE; INSULIN LISPRO; PANCREAS ISLET CELL ANTIBODY; VIRUS ANTIGEN;

ABDOMINAL PAIN; ACUTE KIDNEY FAILURE; ADULT; AMYLASE BLOOD LEVEL; ANEMIA; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; CASE REPORT; CELL DESTRUCTION; COLON BIOPSY; COMPUTER ASSISTED TOMOGRAPHY; CONSCIOUSNESS DISORDER; CONTINUOUS INFUSION; CYTOMEGALOVIRUS INFECTION; DIABETIC KETOACIDOSIS; DIABETOGENESIS; DISEASE ASSOCIATION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ENTEROCOLITIS; FEMALE; FEVER; FLU LIKE SYNDROME; FLUID THERAPY; HEMATOCHEZIA; HEMOGLOBIN BLOOD LEVEL; HETEROZYGOTE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPOTENSION; INSULIN DEPENDENT DIABETES MELLITUS; LABORATORY TEST; LIVER DYSFUNCTION; LUNG EMPHYSEMA; MOLECULAR MIMICRY; PANCREAS ISLET BETA CELL; RHABDOMYOLYSIS; TACHYPNEA; THROMBOCYTOPENIA;

AUTOANTIBODIES; CYTOMEGALOVIRUS INFECTIONS; DIABETES MELLITUS, TYPE 1; FEMALE; HUMANS; MIDDLE AGED; TREATMENT OUTCOME;

EID: 34547900661     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.46.6395     Document Type: Article

References (13)

1. Eisenbarth GS. Type 1 diabetes mellitus. In: Joslin's Diabetes Mellitus, 14th ed. Kahn CR, Weir GC, King GL, et al, Eds. Lippincott Williams & Wilkins, New York 2005: 399-424.
2. Takeda N, Isonuma H, Sekiya S, Ebe T, Matsumoto T, Watanabe K. Studies of anti-cytomegalovirus IgG antibody positive rate and cytornegalovirus mononucleosis in adults. The Journal of the Japanese Association for Infectious Diseases 75: 775-779, 2001 (in Japanese, abstract in English).
3. Imagawa A, Hanafusa T, Miyagawa J, Matsuzawa Y, for the Osaka IDDM Study Group. A novel subtype of type-1 diabetes mellitus characterized by a rapid onset and an absence of diabetes-related antibodies. N Engl J Med 342: 301-307, 2000.
4. Hanafusa T, Imagawa A, Iwahashi H, et al. Report of Japan Diabetes Society Committee on fulminant type 1 diabetes mellitus research: epidemiological and clinical analysis and proposal of diagnostic criteria. J Japan Diab Soc 48 (Suppl. 1): A1-A13, 2005 (in Japanese, abstract in English).
5. Kawasaki E, Matsuura N, Eguchi K. Type 1 diabetes in Japan. Diabetologia 49: 828-836, 2006.
6. Kawabata Y, Ikegami H, Kawaguchi Y, et al. Asian-specific HLA haplotypes reveal heterogeneity of the contribution of HLA-DR and -DQ haplotypes to susceptibility to type 1 diabetes. Diabetes 51: 545-551, 2002.
7. Imagawa A, Hanafusa T, Uchigata Y, et al. Different contribution of class II HLA in fulminant and typical autoimmune type 1 diabetes mellitus. Diabetologia 48: 294-300, 2005.
8. Nakanishi K, Inoko H. Combination of HLA-A24, -DQA1*03, and -DR9 contributes to acute-onset and early complete β-Cell destruction in type 1 diabetes: longitudinal study of residual β-Cell function. Diabetes 55: 1862-1868, 2006.
9. Hiemstra HS, Schloot NC, van Veelen PA, et al. Cytomegalovirus in autoimmunity: T cell crossreactivity to viral antigen and autoantigen glutamic acid decarboxylase. PNAS 98: 3988-3991, 2001.
10. Suzuki J, Yamauchi M, Mizutani N, Shibata T, Suzuki A, Aoki T, Sobajima H. A case of type 2 diabetes mellitus associated with cytomegalic colitis. J Japan Diabetes Soc 49: 535-539, 2006 (in Japanese, abstract in English).
11. Masuzawa M, Motojima S. A case of hypersensitivity syndrome caused by re-activation of cytomegalovirus complicated with non-autoimmune type 1 diabetes and painless thyroiditis. Clinical Endocrinol 52: 124-128, 2004 (in Japanese).
12. Yasumoto N, Hara M, Kitamoto Y, Nakayama M, Sato T. Cytomegalovirus infection associated with acute pancreatitis, rhabdomyolysis and renal failure. Intern Med 31: 426-430, 1992.
13. Kotani R, Nagata M, Imagawa A, et al. T lymphocyte response against pancreatic beta cell antigens in fulminant Type 1 diabetes. Diabetologia 47: 1285-1291, 2004.