Implementation of antibiotic rotation protocol improves antibiotic susceptibility profile in a surgical intensive care unit

Journal of Trauma - Injury, Infection and Critical Care

Volumn 63, Issue 2, 2007, Pages 307-311

  Bennett, Kyla M ^a   Scarborough, John E ^a   Sharpe, Michelle ^a   Dodds Ashley, Elizabeth ^a   Kaye, Keith S ^a   Hayward, Thomas Z ^b   Vaslef, Steven N ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b INDIANA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Antibiotic resistance; Antibiotic rotation; Nosocomial infections

Indexed keywords

CEFTAZIDIME; CILASTATIN PLUS IMIPENEM; CIPROFLOXACIN; PIPERACILLIN; TAZOBACTAM;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATION; ESCHERICHIA COLI; GRAM NEGATIVE INFECTION; HUMAN; INTENSIVE CARE UNIT; KLEBSIELLA PNEUMONIAE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; ROTATION; STATISTICAL SIGNIFICANCE;

ANTI-BACTERIAL AGENTS; CEFTAZIDIME; CIPROFLOXACIN; CLINICAL PROTOCOLS; CRITICAL CARE; CROSS INFECTION; DRUG RESISTANCE, BACTERIAL; FEMALE; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; IMIPENEM; INCIDENCE; INTENSIVE CARE UNITS; MALE; MICROBIAL SENSITIVITY TESTS; PENICILLANIC ACID; PIPERACILLIN; PROBABILITY; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME;

EID: 34547875082     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e318120595e     Document Type: Article

References (25)

1. Brown EM, Nathwani D. Antibiotic cycling or rotation: a systematic review of the evidence of efficacy. J Antimicrob Chemother. 2005;55:6-9.
2. Fridkin SK. Routine cycling of antimicrobial agents as an infection-control measure. Clin Infect Dis. 2003;36:1438-1444.
3. Kollef MH. Optimizing antibiotic therapy in the intensive care unit setting. Crit Care. 2001;5:189-195.
4. Kollef MH. Is there a role for antibiotic cycling in the intensive care unit? Crit Care Med. 2001;29(Suppl 4):N135-N142.
5. Niederman MS. Is "crop rotation" of antibiotics the solution to a "resistant" problem in the ICU? Am J Respir Crit Care Med. 1997;156:1029-1031.
6. Niederman MS. Impact of antibiotic resistance on clinical outcomes and the cost of care. Crit Care Med. 2001;29(Suppl 4):N114-N120.
7. Warren DK, Fraser VJ. Infection control measures to limit antimicrobial resistance. Crit Care Med. 2001;29(Suppl 4):N128-N134.
8. Warren DK, Hill HA, Merz LR, et al. Cycling empirical antibiotic agents to prevent emergence of antimicrobial-resistant Gram-negative bacteria among intensive care unit patients. Crit Care Med. 2004;32:2450-2456.
9. McGowan JJ. Strategies for study of the role of cycling antimicrobial use and resistance. Infect Control Hosp Epidemiol. 2000;21:S36-S43.
10. Allegranzi B, Luzzati R, Luzzani A, et al. Impact of antibiotic changes in empirical therapy on antimicrobial resistance in intensive care unit-acquired infections. J Hosp Infect. 2002;52:136-140.
11. Bradley SJ, Wilson AL, Allen MC, et al. The control of hyperendemic glycopeptide-resistant Enterococcus spp. on a haematology unit by changing antibiotic usage. J Antimicrob Chemother. 1999;43:261-266.
12. Gerding DN, Larson TA. Aminoglycoside resistance in gram-negative bacilli during increased amikacin use: comparison of experience in 14 United States hospitals with experience in the Minneapolis Veterans Administration Medical Center. Am J Med. 1985;79(1A):1-7.
13. Gerding DN, Larson TA, Hughes RA, Weiler M, Shanholtzer C, Peterson LR. Aminoglycoside resistance and aminoglycoside usage: ten years of experience in one hospital. Antimicrob Agents Chemother. 1991;35:1284-1290.
14. Gruson D, Hilbert G, Vargas F, et al. Rotation and restricted use of antibiotics in a medical intensive care unit: impact on the incidence of ventilator-associated pneumonia caused by antibiotic-resistant gram-negative bacteria. Am J Respir Crit Care Med. 2000;162:837-843.
15. Gruson D, Hilbert G, Vargas F, et al. Strategy of antibiotic rotation: long-term effect on incidence and susceptibilities of Gram-negative bacilli responsible for ventilator-associated pneumonia. Crit Care Med. 2003;31:1908-1914.
16. Kollef MH, Vlasnik J, Sharpless L, Pasque C, Murphy D, Fraser V. Scheduled change of antibiotic classes: a strategy to decrease the incidence of ventilator-associated pneumonia. Am J Respir Crit Care Med. 1997;156:1040-1048.
17. Martinez JA, Nicolas JM, Marco F, et al. Comparison of antimicrobial cycling and mixing strategies in two medical intensive care units. Crit Care Med. 2006;34:329-336.
18. Puzniak LA, Mayfield J, Leet T, Kollef M, Mundy LM. Acquisition of vancomycin-resistant enterococci during scheduled antimicrobial rotation in an intensive care unit. Clin Infect Dis. 2001;33:151-157.
19. Toltzis P, Dul MJ, Hoyen C, et al. The effect of antibiotic rotation on colonization with antibiotic-resistant bacilli in a neonatal intensive care unit. Pediatrics. 2002;110:707-711.
20. Young EJ, Sewell CM, Koza MA, Clarridge JE. Antibiotic resistance patterns during aminoglycoside restriction. Am J Med Sci. 1985;290:223-227.
21. Bonten MJ, Austin DJ, Lipsitch M. Understanding the spread of antibiotic-resistant pathogens in hospitals: mathematical models as tools for control. Clin Infect Dis. 2001;33:1739-1746.
22. Raymond DP, Pelletier SJ, Crabtree TD, et al. Impact of a rotating empiric antibiotic schedule on infectious mortality in an intensive care unit. Crit Care Med. 2001;29:1101-1108.
23. Dominguez EA, Smith TL, Reed E, Sanders CC, Sanders WE Jr. A pilot study of antibiotic cycling in a hematology-oncology unit. Infect Control Hosp Epidemiol. 2000;21(Suppl 1):S4 -S8.
24. van Loon HJ, Vriens MR, Fluit AC. Antibiotic rotation and development of gram-negative antibiotic resistance. Am J Respir Crit Care Med. 2005;171:480-487.
25. Kollef MH, Ward S, Sherman G, et al. Inadequate treatment of nosocomial infections is associated with certain empiric antibiotic choices. Crit Care Med. 2000;28:3456-3464.