Effects of the serotonin 5-HT7 receptor antagonist SB-269970 on the inhibition of dopamine neuronal firing induced by amphetamine

European Journal of Pharmacology

Volumn 570, Issue 1-3, 2007, Pages 72-76

  Mnie Filali, Ouissame ^a   Dahan, Lionel ^a   Zimmer, Luc ^a   Haddjeri, Nasser ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

Amphetamine; Dopamine; SB 269970; Serotonin 7 (5 HT7) receptors; Substantia nigra pars compacta; Ventral tegmental area

Indexed keywords

3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; AMPHETAMINE; SEROTONIN 7 RECEPTOR; SEROTONIN ANTAGONIST;

ACUTE DRUG ADMINISTRATION; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC ACTIVITY; DOPAMINERGIC NERVE CELL; DRUG EFFECT; MALE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM;

AMPHETAMINE; ANIMALS; DOPAMINE; MALE; NEURONS; PHENOLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; SUBSTANTIA NIGRA; SULFONAMIDES; VENTRAL TEGMENTAL AREA;

EID: 34547849652     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.05.037     Document Type: Article

References (29)

1. Browder S., German D.C., and Shore P.A. Midbrain dopamine neurons: differential responses to amphetamine isomers. Brain Res. 207 (1981) 333-342
2. Bubar M.J., and Cunningham K.A. Distribution of serotonin 5-HT(2C) receptors in the ventral tegmental area. Neuroscience 146 (2007) 286-297
3. Bunney B.S., and Aghajanian G.K. d-Amphetamine-induced inhibition of central dopaminergic neurons: mediation by a striato-nigral feedback pathway. Science 192 (1976) 391-393
4. Bunney B.S., and Aghajanian G.K. d-Amphetamine-induced depression of central dopamine neurons: evidence for mediation by both autoreceptors and a striato-nigral feedback pathway. Naunyn-Schmiedeberg's Arch. Pharmacol. 304 (1978) 255-261
5. Bunney B.S., Walters J.R., Roth R.H., and Aghajanian G.K. Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity. J. Pharmacol. Exp. Ther. 185 (1973) 560-571
6. Corvaja N., Doucet G., and Bolam J.P. Ultrastructure and synaptic targets of the raphe-nigral projection in the rat. Neuroscience 55 (1993) 417-427
7. De Deurwaerdere P., Stinus L., and Spampinato U. Opposite change of in vivo dopamine release in the rat nucleus accumbens and striatum that follows electrical stimulation of dorsal raphe nucleus: role of 5-HT3 receptors. J. Neurosci. 18 (1998) 6528-6538
8. Esposito E. Serotonin-dopamine interaction as a focus of novel antidepressant drugs. Curr. Drug Targets 7 (2006) 177-185
9. Faure C., Mnie-Filali O., Scarna H., Debonnel G., and Haddjeri N. Effects of the 5-HT(7) receptor antagonist SB-269970 on rat hormonal and temperature responses to the 5-HT(1A/7) receptor agonist 8-OH-DPAT. Neurosci. Lett. 404 (2006) 122-126
10. Gervais J., and Rouillard C. Dorsal raphe stimulation differentially modulates dopaminergic neurons in the ventral tegmental area and substantia nigra. Synapse 35 (2000) 281-291
11. Hagan J.J., Price G.W., Jeffrey P., Deeks N.J., Stean T., Piper D., Smith M.I., Upton N., Medhurst A.D., Middlemiss D.N., Riley G.J., Lovell P.J., Bromidge S.M., and Thomas D.R. Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist. Br. J. Pharmacol. 130 (2000) 539-548
12. Hedlund P.B., Huitron-Resendiz S., Henriksen S.J., and Sutcliffe J.G. 5-HT7 receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern. Biol. Psychiatry 58 (2005) 831-837
13. Herve D., Pickel V.M., Joh T.H., and Beaudet A. Serotonin axon terminals in the ventral tegmental area of the rat: fine structure and synaptic input to dopaminergic neurons. Brain Res. 435 (1987) 71-83
14. Jones S., and Kauer J.A. Amphetamine depresses excitatory synaptic transmission via serotonin receptors in the ventral tegmental area. J. Neurosci. 19 (1999) 9780-9787
15. Kelly P.H., and Iversen S.D. Selective 6OHDA-induced destruction of mesolimbic dopamine neurons: abolition of psychostimulant-induced locomotor activity in rats. Eur. J. Pharmacol. 40 (1976) 45-56
16. Krobert K.A., Bach T., Syversveen T., Kvingedal A.M., and Levy F.O. The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution. Naunyn-Schmiedeberg's Arch. Pharmacol. 363 (2001) 620-632
17. Kuczenski R., and Segal D. Concomitant characterization of behavioral and striatal neurotransmitter response to amphetamine using in vivo microdialysis. J. Neurosci. 9 (1989) 2051-2065
18. McCreary A.C., Glennon J.C., Ashby C.R., Meltzer H.Y., Li Z., Reinders J.H., Hesselink M.B., Long S.K., Herremans A.H., van Stuivenberg H., Feenstra R.W., and Kruse C.G. SLV313 (1-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-4-[5-(4-fluoro-phenyl)-pyridin-3-ylmethyl]-piperazine monohydrochloride): A novel dopamine D(2) receptor antagonist and 5-HT(1A) receptor agonist potential antipsychotic drug. Neuropsychopharmacology 32 (2007) 78-94
19. Meltzer H.Y., Li Z., Kaneda Y., and Ichikawa J. Serotonin receptors: their key role in drugs to treat schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 27 (2003) 1159-1172
20. Minabe Y., Emori K., and Ashby C.R.J. The depletion of brain serotonin levels by para-chlorophenylalanine administration significantly alters the activity of midbrain dopamine cells in rats: an extracellular single cell recording study. Synapse 22 (1996) 46-53
21. Moukhles H., Bosler O., Bolam J.P., Vallee A., Umbriaco D., Geffard M., and Doucet G. Quantitative and morphometric data indicate precise cellular interactions between serotonin terminals and postsynaptic targets in rat substantia nigra. Neuroscience 76 (1997) 1159-1171
22. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. Fourth Edition (1998), Academic Press, New York
23. Penington N.J., and Reiffenstein R.J. Direct comparison of hallucinogenic phenethylamines and D-amphetamine on dorsal raphe neurons. Eur. J. Pharmacol. 122 (1986) 373-377
24. Pouzet B., Didriksen M., and Arnt J. Effects of the 5-HT(7) receptor antagonist SB-258741 in animal models for schizophrenia. Pharmacol. Biochem. Behav. 71 (2002) 655-665
25. Shi W.X., Pun C.L., Smith P.L., and Bunney B.S. Endogenous DA-mediated feedback inhibition of DA neurons: involvement of both D(1)-and D(2)-like receptors. Synapse 35 (2000) 111-119
26. Stockton M.E., and Rasmussen K. Olanzapine, a novel atypical antipsychotic, reverses d-amphetamine-induced inhibition of midbrain dopamine cells. Psychopharmacology (Berl) 124 (1996) 50-56
27. Van Bockstaele E.J., Cestari D.M., and Pickel V.M. Synaptic structure and connectivity of serotonin terminals in the ventral tegmental area: potential sites for modulation of mesolimbic dopamine neurons. Brain Res. 647 (1994) 307-322
28. Vanhoenacker P., Haegeman G., and Leysen J.E. 5-HT7 receptors: current knowledge and future prospects. Trends Pharmacol. Sci. 21 (2000) 70-77
29. Wang R.Y. Dopaminergic neurons in the rat ventral tegmental area. I. Identification and characterization. Brain Res. Rev. 3 (1981) 123-140