Efficient method development strategy for challenging separation of pharmaceutical molecules using advanced chromatographic technologies

Journal of Chromatography A

Volumn 1163, Issue 1-2, 2007, Pages 145-156

  Xiao, Kang Ping ^a   Xiong, Yuan ^a   Liu, Fang Zhu ^a   Rustum, Abu M ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Alphamethylepoxide; Betamethylepoxide; Computer assisted chromatographic method development tool (ChromSword); LC Spiderling 9 port column switching system; Method development strategy

Indexed keywords

ALPHAMETHYLEPOXIDE; BETAMETHYLEPOXIDE; COMPUTER-ASSISTED CHROMATOGRAPHIC METHOD DEVELOPMENT TOOL (CHROMSWORD); LC SPIDERLING 9-PORT COLUMN SWITCHING SYSTEM; METHOD DEVELOPMENT STRATEGY;

BIOASSAY; CRYSTAL STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR DYNAMICS; PROBABILITY;

DRUG PRODUCTS;

ALPHAMETHYLEPOXIDE; BETAMETHYLEPOXIDE; CARBON; EPOXIDE; METHYL GROUP; STEROID; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; COLUMN CHROMATOGRAPHY; COMPUTER AIDED DESIGN; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROBABILITY; SCREENING TEST;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EPOXY COMPOUNDS; MOLECULAR STRUCTURE; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; STEREOISOMERISM;

BOERHAVIA;

EID: 34547849589     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2007.06.027     Document Type: Article

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