메뉴 건너뛰기




Volumn 52, Issue 9, 2007, Pages 2229-2235

Intragastric nitroglycerin at a vasodilatory dose attenuates acidified aspirin-induced gastric mucosal injury

Author keywords

Acidified aspirin; Gastric blood flow; Gastric mucosal injury; Gastric volume; Nitroglycerin

Indexed keywords

ACETYLSALICYLIC ACID; GLYCERYL TRINITRATE; NITROJET; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

EID: 34547843603     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-006-9266-2     Document Type: Article
Times cited : (1)

References (33)
  • 1
    • 0028929443 scopus 로고
    • Prophalactic aspirin and risk of peptic ulcer bleeding
    • Weil J, Colin-Jones D, Langman MJS, et al. (1995) Prophalactic aspirin and risk of peptic ulcer bleeding. Br Med J 310:827-830
    • (1995) Br Med J , vol.310 , pp. 827-830
    • Weil, J.1    Colin-Jones, D.2    Langman, M.J.S.3
  • 2
    • 0036828646 scopus 로고    scopus 로고
    • Risk of upper gastrointestinal bleeding in patients taking low-dose aspirin for the prevention of cardiovascular diseases
    • 11
    • Serrano P, Lanas A, Arroyo MT, Ferreira IJ (2002) Risk of upper gastrointestinal bleeding in patients taking low-dose aspirin for the prevention of cardiovascular diseases. Alimentary Pharmacol Ther 16(11):1945-1953
    • (2002) Alimentary Pharmacol Ther , vol.16 , pp. 1945-1953
    • Serrano, P.1    Lanas, A.2    Arroyo, M.T.3    Ferreira, I.J.4
  • 3
    • 0037190695 scopus 로고    scopus 로고
    • Evaluation of the benefits and risks of low-dose aspirin in the secondary prevention of cardiovascular and cerebrovascular events
    • 19
    • Weisman SM, Graham DY (2002) Evaluation of the benefits and risks of low-dose aspirin in the secondary prevention of cardiovascular and cerebrovascular events. Arch Intern Med 162(19):2197-2202
    • (2002) Arch Intern Med , vol.162 , pp. 2197-2202
    • Weisman, S.M.1    Graham, D.Y.2
  • 4
    • 23944513240 scopus 로고    scopus 로고
    • Upper gastrointestinal haemorrhage associated with low-dose aspirin and anti-thrombotic drugs-a 6-year analysis and comparison with non-steroidal anti-inflammatory drugs
    • 4
    • Taha AS, Angerson WJ, Knill-Jones RP, Blatchford O (2005) Upper gastrointestinal haemorrhage associated with low-dose aspirin and anti-thrombotic drugs-a 6-year analysis and comparison with non-steroidal anti-inflammatory drugs. Alimentary Pharmacol Ther 22(4):285-289
    • (2005) Alimentary Pharmacol Ther , vol.22 , pp. 285-289
    • Taha, A.S.1    Angerson, W.J.2    Knill-Jones, R.P.3    Blatchford, O.4
  • 5
    • 23944506639 scopus 로고    scopus 로고
    • Minidose aspirin and gastrointestinal bleeding-a retrospective, case-control study in hospitalized patients
    • 9
    • Sapoznikov B, Vilkin A, Hershkovici M, Fishman M, Eliakim R, Niv Y (2005) Minidose aspirin and gastrointestinal bleeding-a retrospective, case-control study in hospitalized patients. Dig Dis Sci 50(9):1621-1624
    • (2005) Dig Dis Sci , vol.50 , pp. 1621-1624
    • Sapoznikov, B.1    Vilkin, A.2    Hershkovici, M.3    Fishman, M.4    Eliakim, R.5    Niv, Y.6
  • 6
    • 0034699601 scopus 로고    scopus 로고
    • Nitrovasodilators, low-dose aspirin, other nonsteroidal antiinflammatory drugs, and the risk of upper gastrointestinal bleeding
    • 12
    • Lanas A, Bajador E, Serrano P, Fuentes J, Carreno S, Guardia J, Sanz M, Montoro M, Sainz R (2000) Nitrovasodilators, low-dose aspirin, other nonsteroidal antiinflammatory drugs, and the risk of upper gastrointestinal bleeding. N Engl J Med 343(12):834-839
    • (2000) N Engl J Med , vol.343 , pp. 834-839
    • Lanas, A.1    Bajador, E.2    Serrano, P.3    Fuentes, J.4    Carreno, S.5    Guardia, J.6    Sanz, M.7    Montoro, M.8    Sainz, R.9
  • 7
    • 0024844763 scopus 로고
    • Endothelium-derived relaxing factor (nitric oxide) has protective actions in the stomach
    • 20
    • MacNaughton WK, Cirino G, Wallace JL (1989) Endothelium-derived relaxing factor (nitric oxide) has protective actions in the stomach. Life Sci 45(20):1869-1876
    • (1989) Life Sci , vol.45 , pp. 1869-1876
    • MacNaughton, W.K.1    Cirino, G.2    Wallace, J.L.3
  • 8
    • 0025370449 scopus 로고
    • Effect of endothelium-derived relaxing factor on the gastric lesion induced by HCl in rats
    • 3
    • Kitagawa H, Takeda F, Kohei H (1990) Effect of endothelium-derived relaxing factor on the gastric lesion induced by HCl in rats. J Pharmacol Exp Ther 253(3):1133-1137
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 1133-1137
    • Kitagawa, H.1    Takeda, F.2    Kohei, H.3
  • 9
    • 0034682955 scopus 로고    scopus 로고
    • Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats
    • 13
    • Tashima K, Fujita A, Umeda M, Takeuchi K (2000) Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats. Life Sci 67(13):1639-1652
    • (2000) Life Sci , vol.67 , pp. 1639-1652
    • Tashima, K.1    Fujita, A.2    Umeda, M.3    Takeuchi, K.4
  • 10
    • 0034910806 scopus 로고    scopus 로고
    • Lack of gastric toxicity of nitric oxide-releasing indomethacin, NCX-530, in experimental animals
    • 8
    • Takeuchi K, Mizoguchi H, Araki H, Komoike Y, Suzuki K (2001) Lack of gastric toxicity of nitric oxide-releasing indomethacin, NCX-530, in experimental animals. Dig Dis Sci 46(8):1805-1818
    • (2001) Dig Dis Sci , vol.46 , pp. 1805-1818
    • Takeuchi, K.1    Mizoguchi, H.2    Araki, H.3    Komoike, Y.4    Suzuki, K.5
  • 11
    • 0036908256 scopus 로고    scopus 로고
    • The role of reactive oxygen species in action of nitric oxide-donors on stress-induced gastric mucosal lesions
    • 4; Pt 2
    • Kwiecien S, Brzozowski T, Konturek PC, Konturek SJ (2002) The role of reactive oxygen species in action of nitric oxide-donors on stress-induced gastric mucosal lesions. J Physiol Pharmacol 53(4; Pt 2):761-773
    • (2002) J Physiol Pharmacol , vol.53 , pp. 761-773
    • Kwiecien, S.1    Brzozowski, T.2    Konturek, P.C.3    Konturek, S.J.4
  • 13
    • 0025967379 scopus 로고
    • Mechanism of intragastric nicotine protection against ethanol-induced gastric injury
    • Endoh K, Baker M, Leung FW (1991) Mechanism of intragastric nicotine protection against ethanol-induced gastric injury. Dig Dis Sci 36:39-46
    • (1991) Dig Dis Sci , vol.36 , pp. 39-46
    • Endoh, K.1    Baker, M.2    Leung, F.W.3
  • 15
    • 0023177748 scopus 로고
    • Reflectance spectrophotometry for the assessment of gastroduodenal mucosal perfusion
    • Leung FW, Morishita T, Livingston EH, Reedy T, Guth PH (1987) Reflectance spectrophotometry for the assessment of gastroduodenal mucosal perfusion. Am J Physiol 252:G797-G804
    • (1987) Am J Physiol , vol.252
    • Leung, F.W.1    Morishita, T.2    Livingston, E.H.3    Reedy, T.4    Guth, P.H.5
  • 16
    • 0038342027 scopus 로고    scopus 로고
    • Role of acute elevation of portal venous pressure by exogenous glucagon on gastric mucosal injury in rats with portal hypertension
    • 9
    • Tsui CP, Sung JJ, Leung FW (2003) Role of acute elevation of portal venous pressure by exogenous glucagon on gastric mucosal injury in rats with portal hypertension. Life Sci 73(9):1115-1129
    • (2003) Life Sci , vol.73 , pp. 1115-1129
    • Tsui, C.P.1    Sung, J.J.2    Leung, F.W.3
  • 17
    • 0026524975 scopus 로고
    • Role of capsaicin-sensitive afferent nerves in mucosal injury and injury-induced hyperemia in rat colon
    • Leung FW (1992) Role of capsaicin-sensitive afferent nerves in mucosal injury and injury-induced hyperemia in rat colon. Am J Physiol 262:G332-G337
    • (1992) Am J Physiol , vol.262
    • Leung, F.W.1
  • 18
    • 0027479069 scopus 로고
    • Inhibition of spinal afferent nerve-mediated gastric hyperemia by nicotine-Role of ganglionic blockade
    • Leung FW (1993) Inhibition of spinal afferent nerve-mediated gastric hyperemia by nicotine-Role of ganglionic blockade. Am J Physiol 264:H1087-H1092
    • (1993) Am J Physiol , vol.264
    • Leung, F.W.1
  • 20
    • 0035019326 scopus 로고    scopus 로고
    • Adaptive gastric cytoprotection is mediated by prostaglandin EP1 receptors: A study using rats and knockout mice
    • 3
    • Takeuchi K, Araki H, Umeda M, Komoike Y, Suzuki K (2001) Adaptive gastric cytoprotection is mediated by prostaglandin EP1 receptors: a study using rats and knockout mice. J Pharmacol Exp Ther 297(3):1160-1165
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 1160-1165
    • Takeuchi, K.1    Araki, H.2    Umeda, M.3    Komoike, Y.4    Suzuki, K.5
  • 21
    • 7044272244 scopus 로고    scopus 로고
    • Preventive activity of pyrrolizidine alkaloids from Seneciobrasiliensis (Asteraceae) on gastric and duodenal induced ulcer on mice and rats
    • 2-3
    • Toma W, Trigo JR, de Paula AC, Brito AR (2004) Preventive activity of pyrrolizidine alkaloids from Seneciobrasiliensis (Asteraceae) on gastric and duodenal induced ulcer on mice and rats. J Ethnopharmacol 95(2-3):345-351
    • (2004) J Ethnopharmacol , vol.95 , pp. 345-351
    • Toma, W.1    Trigo, J.R.2    De Paula, A.C.3    Brito, A.R.4
  • 22
    • 0024431591 scopus 로고
    • Mechanism of the potentiation of aspirin-induced gastric lesions by exposure to cold in rats: Role of acid secretion, mucosal blood flow and gastric mucosal prostanoid content
    • Robert A, Leung FW, Kaiser DG, Guth PH (1989) Mechanism of the potentiation of aspirin-induced gastric lesions by exposure to cold in rats: role of acid secretion, mucosal blood flow and gastric mucosal prostanoid content. Gastroenterology 97:1147-1158
    • (1989) Gastroenterology , vol.97 , pp. 1147-1158
    • Robert, A.1    Leung, F.W.2    Kaiser, D.G.3    Guth, P.H.4
  • 23
    • 0027538488 scopus 로고
    • Involvement of alpha-2-adrenoceptors in the mechanism of intragastric nicotine protection against ethanol injury in rat stomach
    • Endoh K, Kao J, Baker M, Leung FW (1993) Involvement of alpha-2-adrenoceptors in the mechanism of intragastric nicotine protection against ethanol injury in rat stomach. Dig Dis Sci 38:713-721
    • (1993) Dig Dis Sci , vol.38 , pp. 713-721
    • Endoh, K.1    Kao, J.2    Baker, M.3    Leung, F.W.4
  • 24
    • 0029015265 scopus 로고
    • Aggravation of gastric mucosal lesions in rat stomach by tobacco cigarette smoke
    • Iwata F, Zhang XY, Leung FW (1995) Aggravation of gastric mucosal lesions in rat stomach by tobacco cigarette smoke. Dig Dis Sci 40:1118-1124
    • (1995) Dig Dis Sci , vol.40 , pp. 1118-1124
    • Iwata, F.1    Zhang, X.Y.2    Leung, F.W.3
  • 25
    • 0024566966 scopus 로고
    • Resistance or conductance for expression of arterial vascular tone
    • 2
    • Lautt WW (1989) Resistance or conductance for expression of arterial vascular tone. Microvasc Res 37(2):230-236
    • (1989) Microvasc Res , vol.37 , pp. 230-236
    • Lautt, W.W.1
  • 26
    • 0028800359 scopus 로고
    • Anti-thrombotic effects of a nitric oxide-releasing, gastric-sparing aspirin derivative
    • 6
    • Wallace JL, McKnight W, Del Soldato P, Baydoun AR, Cirino G (1995) Anti-thrombotic effects of a nitric oxide-releasing, gastric-sparing aspirin derivative. J Clin Invest 96(6):2711-2718
    • (1995) J Clin Invest , vol.96 , pp. 2711-2718
    • Wallace, J.L.1    McKnight, W.2    Del Soldato, P.3    Baydoun, A.R.4    Cirino, G.5
  • 27
    • 0028344296 scopus 로고
    • Protection against gastric ischemia-reperfusion injury by nitric oxide generators
    • 2
    • Andrews FJ, Malcontenti-Wilson C, O'Brien PE (1994) Protection against gastric ischemia-reperfusion injury by nitric oxide generators. Dig Dis Sci 39(2):366-373
    • (1994) Dig Dis Sci , vol.39 , pp. 366-373
    • Andrews, F.J.1    Malcontenti-Wilson, C.2    O'Brien, P.E.3
  • 28
    • 0031408178 scopus 로고    scopus 로고
    • Reduction of shock-induced gastric damage by a nitric oxide-releasing aspirin derivative: Role of neutrophils
    • 6; Pt 1
    • Wallace JL, McKnight W, Wilson TL, Del Soldato P, Cirino G (1997) Reduction of shock-induced gastric damage by a nitric oxide-releasing aspirin derivative: role of neutrophils. Am J Physiol 273(6; Pt 1):G1246-G1251
    • (1997) Am J Physiol , vol.273
    • Wallace, J.L.1    McKnight, W.2    Wilson, T.L.3    Del Soldato, P.4    Cirino, G.5
  • 30
    • 0027137363 scopus 로고
    • Role of L-arginine-derived nitric oxide in cholinergic dilation of gastric arterioles
    • 6; Pt 2
    • Chen RY, Ross G, Chyu KY, Guth PH (1993) Role of L-arginine-derived nitric oxide in cholinergic dilation of gastric arterioles. Am J Physiol 265(6; Pt 2):H2110-H2116
    • (1993) Am J Physiol , vol.265
    • Chen, R.Y.1    Ross, G.2    Chyu, K.Y.3    Guth, P.H.4
  • 31
    • 0023253326 scopus 로고
    • Effect of aspirin plus hydrochloric acid on the gastric mucosal microcirculation
    • 4
    • Kitahora T, Guth PH (1987) Effect of aspirin plus hydrochloric acid on the gastric mucosal microcirculation. Gastroenterology 93(4):810-817
    • (1987) Gastroenterology , vol.93 , pp. 810-817
    • Kitahora, T.1    Guth, P.H.2
  • 32
    • 24644475670 scopus 로고    scopus 로고
    • Vascular dysfunction and ischemic destruction of tissue in Streptococcus pyogenes infection: The role of streptolysin O-induced platelet/neutrophil complexes
    • 6
    • Bryant AE, Bayer CR, Chen RY, Guth PH, Wallace RJ, Stevens DL (2005) Vascular dysfunction and ischemic destruction of tissue in Streptococcus pyogenes infection: the role of streptolysin O-induced platelet/neutrophil complexes. J Infect Dis 192(6):1014-1022
    • (2005) J Infect Dis , vol.192 , pp. 1014-1022
    • Bryant, A.E.1    Bayer, C.R.2    Chen, R.Y.3    Guth, P.H.4    Wallace, R.J.5    Stevens, D.L.6
  • 33
    • 0021879528 scopus 로고
    • Gastric mucosal blood flow in rats after administration of 16, 16 dmPGE2 given in a cytoprotective dose
    • Leung FW, Robert A, Guth PH (1985) Gastric mucosal blood flow in rats after administration of 16, 16 dmPGE2 given in a cytoprotective dose. Gastroenterology 88:1948-1953
    • (1985) Gastroenterology , vol.88 , pp. 1948-1953
    • Leung, F.W.1    Robert, A.2    Guth, P.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.