Prevention of ochratoxin A-induced neural tube defects by folic acid in the genetic polydactyly/arhinencephaly mouse, Pdn/Pdn

Congenital Anomalies

Volumn 47, Issue 3, 2007, Pages 90-96

  Katagiri, Ryu Ichi ^a   Kurome, Maho ^a   Teshima, Yuko ^a   Ueta, Etsuko ^a   Naruse, Ichiro ^a  

^a TOTTORI UNIVERSITY   (Japan)

Author keywords

Fgf8; Folic acid; Gli3; Neural tube defect; NTD

Indexed keywords

FOLIC ACID; OCHRATOXIN;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG BLOOD LEVEL; DRUG EFFECT; EMBRYO; GENE EXPRESSION; GENE OVEREXPRESSION; GENOTYPE; HOLOPROSENCEPHALY; IN SITU HYBRIDIZATION; MATERNAL SERUM; MOUSE; NEURAL TUBE DEFECT; NEUROTOXICITY; NONHUMAN; POLYDACTYLY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; DOWN-REGULATION; FOLIC ACID; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOTYPE; HOLOPROSENCEPHALY; IN SITU HYBRIDIZATION; MICE; MICE, TRANSGENIC; MODELS, GENETIC; NEURAL TUBE DEFECTS; OCHRATOXINS; POLYDACTYLY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

MUS;

EID: 34547815597     PISSN: 09143505     EISSN: 17414520     Source Type: Journal    
DOI: 10.1111/j.1741-4520.2007.00152.x     Document Type: Article

References (51)

1. Acampora D, Avantaggiato V, Tuorto F, Simeone A (1997) Genetic control of brain morphogenesis through Otx gene dosage requirement. Development 124 : 3639 3650.
2. Aoto K, Nishimura T, Eto K, Motoyama J (2002) Mouse GLI3 regulates Fgf8 expression and apoptosis in the developing neural tube, face, and limb bud. Dev Biol 251 : 320 332.
3. Barbera JP, Rodriguez TA, Greene ND et al. (2002) Folic acid prevents exencephaly in Cited2 deficient mice. Hum Mol Genet 11 : 283 293.
4. Brown MH, Szezech GM, Purmalis BP (1976) Teratogenic and toxic effects of ochratoxin A in rats. Toxicol Appl Pharmacol 37 : 331 338.
5. Campbell LR, Dayton DH, Sohol GS (1986) Neural tube defects: A review of human and animal studies on the etiology of neural tube defects. Teratology 34 : 171 187.
6. Carter M, Ulrich S, Oofuji Y, Williams DA, Ross ME (1999) Crooked tail (Cd) models human folate-responsive neural tube defects 1. Hum Mol Genet 8 : 2199 2204.
7. Fleming A, Copp AJ (1998) Embryonic folate metabolism and mouse neural tube defects. Science 280 : 2107 2109.
8. Garel S, Huffman KJ, Rubenstein JLR (2003) Molecular regionalization of the neocortex is disrupted in Fgf8 hypomorphic mutants. Development 130 : 1903 1914.
9. Green NS (2002) Folic acid supplementation and prevention of birth defects. J Nutr 132 (Suppl. 2356S 2360S.
10. Greig DM (1926) Oxycephaly. Edin Med J 33 : 189 218.
11. Hayasaka I, Nakatsuka T, Fujii T, Naruse I, Oda S (1980) Polydactyly Nagoya, Pdn: A new mutant gene in the mouse. Jikken Dobutsu (Exp Anim) 29 : 391 395.
12. Hongo T, Hakuba A, Shiota K, Naruse I (2000) Suckling dysfuction caused by defects in the olfactory system in genetic arhinencephaly mice. Biol Neonat 78 : 293 299.
13. Hood RD, Naughton MJ, Hayes AW (1978) Prenatal effects of Ochratoxin A in hamsters. Teratology 13 : 11 14.
14. Jonyn FE, Maxwell SM, Handrickse RG (1995) Human fetal exposure to ochratoxin A and aflatoxins. Ann Trop Paediatr 15 : 3 9.
15. Kuschel S, Rüther U, Theil T (2003) A disrupted balance between Bmp/Wnt and Fgf signaling underlies the ventralization of the Gli3 mutant telencephalon. Dev Biol 260 : 484 495.
16. Maekawa M, Ohta K, Katagiri R, Ueta E, Naruse I (2005) Exencephaly induction by valproic acid in the geneticpolydactyly/arhinencephaly mouse, Pdn/Pdn. Congenit Anom Kyoto 45 : 132 136.
17. Mayura K, Reddy RV, Hayes AW, Berndt WO (1982) Embryocidal, fetotoxic and teratogenic effects of ochratoxin A in rats. Toxicology 25 : 175 185.
18. Naruse I, Kameyama Y (1982) Morphogenesis of genetic preaxial polydactyly, Polydactyly Nagoya, Pdn, in mice. Congenit Anom Kyoto 22 : 137 144.
19. Naruse I, Kato K, Asano T, Suzuki F, Kameyama Y (1990) Developmental brain abnormalities accompanied with the retarded production of S-100, protein in genetic polydactyly mice. Dev Brain Res 51 : 253 258.
20. Naruse I, Keino H (1995) Apoptosis in the developing CNS. Prog Neurobiol 47 : 135 155.
21. Naruse I, Keino H, Masaki S, Yamada Y (2000) Mechanism of polydactyly manifestation in mice and its extrapolation to humans. Congenit Anom Kyoto 40 (Suppl. S25 S33.
22. Naruse I, Keino H, Yamada Y, Masaki S, Hui CC (2001) Phenotypic differences in the brains and limbs of mutant mice caused by differences of Gli3 gene expression levels. Congenit Anom Kyoto 41 : 89 94.
23. Naruse I, Ueta E (2002) Hydrocephalus manifestation in the genetic polydactyly/arhinencephaly mouse (Pdn/Pdn). Congenit Anom Kyoto 42 : 27 31.
24. Naruse I, Ueta E, Maekawa M, Ohta K (2005) Molecular analyses in the mouse homolog of Greig cephalopolysyndactyly syndrome (GCPS). Trend Dev Biol 1 : 83 89.
25. Ohta K, Maekawa M, Katagiri R, Ueta E, Naruse I (2006) Genetic susceptibility in the neural tube defects induced by ochratoxin A in the genetic arhinencephaly mouse, Pdn/Pdn. Congenit Anom Kyoto 46 : 144 148.
26. Padmanabhan R, Shafiullah MM (2003) Amelioration of sodium valproate-induced neural tube defects in mouse fetuses by maternal folic acid supplementation during gestation. Congenit Anom Kyoto 43 : 29 40.
27. Persad VL, Van den Hof MC, Dube JM, Jimmer P (2002) Incidence of open neural tube defecs in Nova Scotia after folic acid fortification. CMAJ 167 : 241 245.
28. Piedrahita JA, Oetama B, Bennett GD et al. (1999) Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development. Nat Genet 23 : 228 232.
29. Postupolski J, Karlowski K, Kubik P (2006) Ochratoxin A in maternal and foetal blood and in maternal milk. Rocz Panstw Zakl Hig 57 : 23 30.
30. Rosano A, Smithells D, Cacciani L et al. (1999) Time trends in neural tube defects prevents prevalence in relation to preventive strategies: An international study. J Epidemiol Community Health 53 : 630 635.
31. Sadler TW, Merrill AH, Victorial L et al. (2002) Prevention of fumonisin b1-induced neural tube defects by folic acid. Teratology 66 : 169 176.
32. Saitsu H, Ishibashi M, Nakano H, Shiota K (2003) Spatial and temporal expression of folate-binding protein 1 (Fbp1) is closely associated with anterior neural tube closure in mice. Dev Dyn 226 : 112 117.
33. Shin JH, Shiota K (1999) Folic acid supplementation of pregnant mice suppresses heat-induced neural tube defects in the offspring. J Nutr 129 : 2070 2073.
34. Simeone A, Gulisano M, Acampora D, Stornaiuolo A, Rambaldi M, Boncinelli E (1992) Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J 11 : 2541 2550.
35. Skaug MA, Stormer FC, Saugstad OD (1998) Ochratoxin A: A naturally occurring mycotoxin found in human milk samples from Norway. Acta Paediatr 87 : 1275 1278.
36. Storm EE, Rubenstein JL, Martin GR (2003) Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain. Proc Natl Acad Sci USA 100 : 1757 1762.
37. Suda Y, Hossain ZM, Kobayashi C et al. (2001) Emx2 directs the development of diencephalon in cooperation with Otx2. Development 128 : 2433 2450.
38. Suda Y, Matsuo I, Kuratani S, Aizawa S (1996) Otx1 function overlaps with Otx2 in development of mouse forebrain and midbrain. Genes Cells 1 : 1031 1044.
39. Theil T, Alvares-Bolada G, Walter A, Rüther U (1999) Gli3 is required for Emx gene expression during dorsal telencephalon development. Development 126 : 3561 3571.
40. Thien H, Rüther U (1999) The mouse mutation Pdn (Polydactyly Nagoya) is caused by the integration of a retrotransposon into the Gli3 gene. Mamm Genome 10 : 205 209.
41. Ueta E, Maekawa M, Morimoto I, Nanba E, Naruse I (2004) Sonic hedgehog expression in Gli3 depressed mouse embryo, Pdn/Pdn. Congenit Anom Kyoto 44 : 27 32.
42. Ueta E, Nanba E, Naruse I (2002) Integration of a transposon into the Gli3 gene in the Pdn mouse. Congenit Anom Kyoto 42 : 318 322.
43. Van der Put NM, Steegers-Theunissen RP, Frosst P et al. (1995) Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida. Lancet 346 : 1070 1071.
44. Vortkamp A, Gessler M, Grzeschik KH (1991) GLI3 zinc finger interrupted by translocation in Greig syndrome families. Nature 352 : 539 540.
45. Wangikar PB, Dwivedi P, Sinha N (2004a) Effect in rats of simultaneous prenatal exposure to ochratoxin A and aflatoxin B1. I. Maternal toxicity and fetal malformations. Birth Defects Res (Part B) 71 : 343 351.
46. Wangikar PB, Dwivedi P, Sharma AK, Sinha N (2004b) Effect in rats of simultaneous prenatal exposure to ochratoxin A and aflatoxin B1. II. Histopathological features of teratological anomalies induced in fetuses. Birth Defects Res (Part B) 71 : 352 358.
47. Wei X, Sulik KK (1996) Pathogenesis of caudal dysgenesis/sirenomelia induced by ochratoxin A in chick embryos. Teratology 53 : 378 391.
48. Wild A, Kalff-Suske M, Vortkamp A, Bornholdt D, König R, Grzeschik KH (1997) Point mutation in human GLI3 cause Greig syndrome. Hum Mol Genet 6 : 1979 1984.
49. Xu Q, Wilkinson DG (1998) In situ hybridization of mRNA with hapten labelled probes. In : Wilkinson DG (ed.). In situ Hybridization: A Practical Approach, 2nd edn. Oxford University Press, Oxford, pp. 87 106.
50. Yoshida M, Suda Y, Matsuo I et al. (1997) Emx1 and Emx2 functions in development of dorsal telencephalon. Development 124 : 101 111.
51. Zhao Q, Behringer RR, Crombrugghe B (1996) Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene. Nat Genet 13 : 275 283.