메뉴 건너뛰기




Volumn 13, Issue 8, 2007, Pages 577-585

Retinoic acid pathway genes show significantly altered expression in uterine fibroids when compared with normal myometrium

Author keywords

ALDH1; CRABP2; CRBP1; Fibroids; Pathway; Retinoic acid

Indexed keywords

ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; CELLULAR RETINOL BINDING PROTEIN 1; CYTOCHROME P450; RETINOIC ACID; RETINOID; RETINOID X RECEPTOR ALPHA; RETINOID X RECEPTOR GAMMA; RETINOL DEHYDROGENASE;

EID: 34547813134     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gam040     Document Type: Article
Times cited : (42)

References (47)
  • 2
    • 18744410984 scopus 로고    scopus 로고
    • Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: New evidence and a systematic review
    • Arslan AA, Gold LI, Mittal K, Suen TC, Belitskaya-Levy I, Tang MS, Toniolo P. Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: New evidence and a systematic review. Hum Reprod 2005;20:852-863.
    • (2005) Hum Reprod , vol.20 , pp. 852-863
    • Arslan, A.A.1    Gold, L.I.2    Mittal, K.3    Suen, T.C.4    Belitskaya-Levy, I.5    Tang, M.S.6    Toniolo, P.7
  • 4
    • 1542710344 scopus 로고    scopus 로고
    • Nuclear retinoid receptors and the transcription of retinoid-target genes
    • Bastien J, Rochette-Egly C. Nuclear retinoid receptors and the transcription of retinoid-target genes. Gene 2004;328:1-16.
    • (2004) Gene , vol.328 , pp. 1-16
    • Bastien, J.1    Rochette-Egly, C.2
  • 6
    • 1642546431 scopus 로고    scopus 로고
    • The chemopreventive agents 4-HPR and DFMO inhibit growth and induce apoptosis in uterine leiomyomas
    • Broaddus RR, Xie S, Hsu CJ, Wang J, Zhang S, Zou C. The chemopreventive agents 4-HPR and DFMO inhibit growth and induce apoptosis in uterine leiomyomas. Am J Obstet Gynecol 2004;190:686-692.
    • (2004) Am J Obstet Gynecol , vol.190 , pp. 686-692
    • Broaddus, R.R.1    Xie, S.2    Hsu, C.J.3    Wang, J.4    Zhang, S.5    Zou, C.6
  • 7
    • 34249717950 scopus 로고    scopus 로고
    • Uterine leiomyomas express a molecular pattern that lowers retinoic acid exposure
    • in press
    • Catherino WH, Malik M. Uterine leiomyomas express a molecular pattern that lowers retinoic acid exposure. Fertil Steril 2007 (in press).
    • (2007) Fertil Steril
    • Catherino, W.H.1    Malik, M.2
  • 9
    • 0032875365 scopus 로고    scopus 로고
    • Physical and functional interactions between cellular retinoic acid binding proteins II and retinoic acid-defendant nuclear complex
    • Delva L, Bastie JN, Rochette-Egly C, Kruiba R, Balitrand N, Despouy G, Chambon P, Chomienne C. Physical and functional interactions between cellular retinoic acid binding proteins II and retinoic acid-defendant nuclear complex. Mol Cell Biol 1999;19:7158-7167.
    • (1999) Mol Cell Biol , vol.19 , pp. 7158-7167
    • Delva, L.1    Bastie, J.N.2    Rochette-Egly, C.3    Kruiba, R.4    Balitrand, N.5    Despouy, G.6    Chambon, P.7    Chomienne, C.8
  • 10
    • 0033588225 scopus 로고    scopus 로고
    • Distinct roles for cellular retinoic acid-binding proteins I and II in regulating signaling by retinoic acid
    • Dong D, Ruuska SE, Levinthal DJ, Noy N. Distinct roles for cellular retinoic acid-binding proteins I and II in regulating signaling by retinoic acid. J Biol Chem 1999;274:23695-23698.
    • (1999) J Biol Chem , vol.274 , pp. 23695-23698
    • Dong, D.1    Ruuska, S.E.2    Levinthal, D.J.3    Noy, N.4
  • 11
    • 0029778148 scopus 로고    scopus 로고
    • Involvement of alcohol dehydrogenase, short-chain dehydrogenase/reductase, aldehyde dehydrogenase, and cytochrome P450 in the control of retinoid signaling by activation of retinoic acid synthesis
    • Duester G. Involvement of alcohol dehydrogenase, short-chain dehydrogenase/reductase, aldehyde dehydrogenase, and cytochrome P450 in the control of retinoid signaling by activation of retinoic acid synthesis. Biochemistry 1996;35:12221-12227.
    • (1996) Biochemistry , vol.35 , pp. 12221-12227
    • Duester, G.1
  • 12
    • 0033911401 scopus 로고    scopus 로고
    • Families of retinoid dehydrogenases regulating vitamin A function: Production of visual pigment and retinoic acid
    • Duester G. Families of retinoid dehydrogenases regulating vitamin A function: Production of visual pigment and retinoic acid. Eur J Biochem 2000;267:4315-4324.
    • (2000) Eur J Biochem , vol.267 , pp. 4315-4324
    • Duester, G.1
  • 13
    • 0037325448 scopus 로고    scopus 로고
    • Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid
    • Duester G, Mic FA, Molotkov A. Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid. Chem Biol Interact 2003;143-144: 201-210.
    • (2003) Chem Biol Interact , vol.143-144 , pp. 201-210
    • Duester, G.1    Mic, F.A.2    Molotkov, A.3
  • 14
    • 12444307577 scopus 로고    scopus 로고
    • Cellular retinol-binding protein I, a regulator of breast epithelial retinoic acid receptor activity, cell differentiation, and tumorigenicity
    • Farias EF, Ong DE, Ghyselinck NB, Nakajo S, Kuppumbatti YS, Mira y Lopez R. Cellular retinol-binding protein I, a regulator of breast epithelial retinoic acid receptor activity, cell differentiation, and tumorigenicity. J Natl Cancer Inst 2005;97:21-29.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 21-29
    • Farias, E.F.1    Ong, D.E.2    Ghyselinck, N.B.3    Nakajo, S.4    Kuppumbatti, Y.S.5    Mira6    Lopez, R.7
  • 15
    • 0036158310 scopus 로고    scopus 로고
    • Hysterectomy rates in the United States 1990-1997
    • Farquhar CM, Steiner CA. Hysterectomy rates in the United States 1990-1997. Obstet Gynecol 2002;99:229-234.
    • (2002) Obstet Gynecol , vol.99 , pp. 229-234
    • Farquhar, C.M.1    Steiner, C.A.2
  • 16
    • 0037677597 scopus 로고    scopus 로고
    • Etiology and pathogenesis of uterine leiomyomas: A review
    • Flake GP, Andersen J, Dixon D. Etiology and pathogenesis of uterine leiomyomas: A review. Environ Health Perspect 2003;111 1037-1054.
    • (2003) Environ Health Perspect , vol.111 , pp. 1037-1054
    • Flake, G.P.1    Andersen, J.2    Dixon, D.3
  • 18
    • 0031955393 scopus 로고    scopus 로고
    • The cloning and characterization of a novel cytochrome P450 family, CYP26, with specificity toward retinoic acid
    • Haque M, Anreola F. The cloning and characterization of a novel cytochrome P450 family, CYP26, with specificity toward retinoic acid. Nutr Rev 1998;56:84-85.
    • (1998) Nutr Rev , vol.56 , pp. 84-85
    • Haque, M.1    Anreola, F.2
  • 19
    • 4544307523 scopus 로고    scopus 로고
    • Molecular characterization of uterine fibroids and its implication for underlying mechanisms of pathogenesis
    • Hoffman PJ, Milliken DB, Gregg LC, Davis RR, Gregg JP. Molecular characterization of uterine fibroids and its implication for underlying mechanisms of pathogenesis. Fertil Steril 2004;82:639-649.
    • (2004) Fertil Steril , vol.82 , pp. 639-649
    • Hoffman, P.J.1    Milliken, D.B.2    Gregg, L.C.3    Davis, R.R.4    Gregg, J.P.5
  • 22
    • 0034856067 scopus 로고    scopus 로고
    • Fibroblast heterogeneity: Existence of functionally distinct Thy 1(+) and Thy 1(-) human female reproductive tract fibroblasts
    • Koumas L, King AE, Critchley HO, Kelly RW, Phipps RP. Fibroblast heterogeneity: Existence of functionally distinct Thy 1(+) and Thy 1(-) human female reproductive tract fibroblasts. Am J Pathol 2001; 159:925-935.
    • (2001) Am J Pathol , vol.159 , pp. 925-935
    • Koumas, L.1    King, A.E.2    Critchley, H.O.3    Kelly, R.W.4    Phipps, R.P.5
  • 23
    • 0036077460 scopus 로고    scopus 로고
    • Differential COX localization and PG release in Thy-1(+) and Thy-1(-) human female reproductive tract fibroblasts
    • Koumas L, Phipps RP. Differential COX localization and PG release in Thy-1(+) and Thy-1(-) human female reproductive tract fibroblasts. Am J Physiol Cell Physiol 2002;283:C599-608.
    • (2002) Am J Physiol Cell Physiol , vol.283
    • Koumas, L.1    Phipps, R.P.2
  • 24
    • 0141648511 scopus 로고    scopus 로고
    • Thy-1 expression in human fibroblast subsets defines myofibroblastic or lipofibroblastic phenotypes
    • Koumas L, Smith TJ, Feldon S, Blumberg N, Phipps RP. Thy-1 expression in human fibroblast subsets defines myofibroblastic or lipofibroblastic phenotypes. Am J Pathol 2003;163:1291-1300.
    • (2003) Am J Pathol , vol.163 , pp. 1291-1300
    • Koumas, L.1    Smith, T.J.2    Feldon, S.3    Blumberg, N.4    Phipps, R.P.5
  • 25
    • 33847225189 scopus 로고    scopus 로고
    • Accumulation of retinoid X receptor-alpha in uterine leiomyomas is associated with a delayed ligand-dependent proteasome-mediated degradation and an alteration of its transcriptional activity
    • Lattuada D, Vigano P, Mangioni S, Sassone J, Di Francesco S, Vignali M, Di Blasio AM. Accumulation of retinoid X receptor-alpha in uterine leiomyomas is associated with a delayed ligand-dependent proteasome-mediated degradation and an alteration of its transcriptional activity. Mol Endocrinol 2007;21:602-612.
    • (2007) Mol Endocrinol , vol.21 , pp. 602-612
    • Lattuada, D.1    Vigano, P.2    Mangioni, S.3    Sassone, J.4    Di Francesco, S.5    Vignali, M.6    Di Blasio, A.M.7
  • 27
    • 0035969097 scopus 로고    scopus 로고
    • Transcriptional regulation in acute promyelocytic leukemia
    • Lin RJ, Sternsdorf T, Tini M, Evans RM. Transcriptional regulation in acute promyelocytic leukemia. Oncogene 2001;20:7204-7215.
    • (2001) Oncogene , vol.20 , pp. 7204-7215
    • Lin, R.J.1    Sternsdorf, T.2    Tini, M.3    Evans, R.M.4
  • 28
    • 24344443662 scopus 로고    scopus 로고
    • Overexpression of the Wnt5b gene in leiomyoma cells: Implications for a role of the Wnt signaling pathway in the uterine benign tumor
    • Mangioni S, Vigano P, Lattuada D, Abbiati A, Vignali M, Di Blasio AM. Overexpression of the Wnt5b gene in leiomyoma cells: Implications for a role of the Wnt signaling pathway in the uterine benign tumor. J Clin Endocrinol Metab 2005;90:5349-5355.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5349-5355
    • Mangioni, S.1    Vigano, P.2    Lattuada, D.3    Abbiati, A.4    Vignali, M.5    Di Blasio, A.M.6
  • 30
    • 0037134450 scopus 로고    scopus 로고
    • Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice
    • Molotkov A, Deltour L, Foglio MH, Cuenca AE, Duester G. Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice. J Biol Chem 2002;277:13804-13811.
    • (2002) J Biol Chem , vol.277 , pp. 13804-13811
    • Molotkov, A.1    Deltour, L.2    Foglio, M.H.3    Cuenca, A.E.4    Duester, G.5
  • 31
    • 0141704319 scopus 로고    scopus 로고
    • Genetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acid
    • Molotkov A, Duester G. Genetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acid. J Biol Chem 2003;278 36085-36090.
    • (2003) J Biol Chem , vol.278 , pp. 36085-36090
    • Molotkov, A.1    Duester, G.2
  • 32
    • 0029846498 scopus 로고    scopus 로고
    • Biochemical pathways of retinoid transport, metabolism, and signal transduction
    • Napoli JL. Biochemical pathways of retinoid transport, metabolism, and signal transduction. Clin Immunol Immunopathol 1996;80 S52-62.
    • (1996) Clin Immunol Immunopathol , vol.80
    • Napoli, J.L.1
  • 33
    • 0034660094 scopus 로고    scopus 로고
    • Retinoid-binding proteins: Mediators of retinoid action
    • Noy N. Retinoid-binding proteins: Mediators of retinoid action. Biochem J 2000;348 Pt 3: 481-495.
    • (2000) Biochem J , vol.348 , Issue.PART 3 , pp. 481-495
    • Noy, N.1
  • 36
  • 37
    • 0037717021 scopus 로고    scopus 로고
    • Differential gene expression in uterine leiomyoma
    • Skubitz KM, Skubitz AP. Differential gene expression in uterine leiomyoma. J Lab Clin Med 2003;141:297-308.
    • (2003) J Lab Clin Med , vol.141 , pp. 297-308
    • Skubitz, K.M.1    Skubitz, A.P.2
  • 38
    • 0035956680 scopus 로고    scopus 로고
    • Uterine fibroids
    • Stewart EA. Uterine fibroids. Lancet 2001;357:293-298.
    • (2001) Lancet , vol.357 , pp. 293-298
    • Stewart, E.A.1
  • 39
    • 0038069373 scopus 로고    scopus 로고
    • Class I alcohol dehydrogenase is highly expressed in normal human mammary epithelium but not in invasive breast cancer: Implications for breast carcinogenesis
    • Triano EA, Slusher LB, Atkins TA, Beneski JT, Gestl SA, Zolfaghari R, Polavarapu R, Frauenhoffer E, Weisz J. Class I alcohol dehydrogenase is highly expressed in normal human mammary epithelium but not in invasive breast cancer: Implications for breast carcinogenesis. Cancer Res 2003;63:3092-3100.
    • (2003) Cancer Res , vol.63 , pp. 3092-3100
    • Triano, E.A.1    Slusher, L.B.2    Atkins, T.A.3    Beneski, J.T.4    Gestl, S.A.5    Zolfaghari, R.6    Polavarapu, R.7    Frauenhoffer, E.8    Weisz, J.9
  • 40
    • 0033571775 scopus 로고    scopus 로고
    • Human uterine leiomyomata express higher levels of peroxisome proliferator-activated receptor gamma, retinoid X receptor alpha, and all-trans refinoic acid than myometrium
    • Tsibris JC, Porter KB, Jazayeri A, Tzimas G, Nau H, Huang H, Kuparadze K, Porter GW, O'Brien WF, Spellacy WN. Human uterine leiomyomata express higher levels of peroxisome proliferator-activated receptor gamma, retinoid X receptor alpha, and all-trans refinoic acid than myometrium. Cancer Res 1999;59:5737-5744.
    • (1999) Cancer Res , vol.59 , pp. 5737-5744
    • Tsibris, J.C.1    Porter, K.B.2    Jazayeri, A.3    Tzimas, G.4    Nau, H.5    Huang, H.6    Kuparadze, K.7    Porter, G.W.8    O'Brien, W.F.9    Spellacy, W.N.10
  • 44
    • 29144520613 scopus 로고    scopus 로고
    • Ethnic differences in expression of the dysregulated proteins in uterine leiomyomata
    • Wei JJ, Chiriboga L, Arslan AA, Melamed J, Yee H, Mittal K. Ethnic differences in expression of the dysregulated proteins in uterine leiomyomata. Hum Reprod 2006;21:57-67.
    • (2006) Hum Reprod , vol.21 , pp. 57-67
    • Wei, J.J.1    Chiriboga, L.2    Arslan, A.A.3    Melamed, J.4    Yee, H.5    Mittal, K.6
  • 46
    • 0030746211 scopus 로고    scopus 로고
    • cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450
    • White JA, Beckett-Jones B, Guo YD, Dilworth FJ, Bonasoro J, Jones G, Petkovich M. cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450. J Biol Chem 1997;272:18538-18541.
    • (1997) J Biol Chem , vol.272 , pp. 18538-18541
    • White, J.A.1    Beckett-Jones, B.2    Guo, Y.D.3    Dilworth, F.J.4    Bonasoro, J.5    Jones, G.6    Petkovich, M.7
  • 47
    • 33645802191 scopus 로고    scopus 로고
    • In vitro culture significantly alters gene expression profiles and reduces differences between myometrial and fibroid smooth muscle cells
    • Zaitseva M, Vollenhoven BJ, Rogers PA. In vitro culture significantly alters gene expression profiles and reduces differences between myometrial and fibroid smooth muscle cells. Mol Hum Reprod 2006; 12:187-207.
    • (2006) Mol Hum Reprod , vol.12 , pp. 187-207
    • Zaitseva, M.1    Vollenhoven, B.J.2    Rogers, P.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.