Flow and mixing characteristics of a retreat curve impeller in a conical-based vessel

Chemical Engineering Research and Design

Volumn 85, Issue 7 A, 2007, Pages 953-962

  Rielly, C D ^a   Habib, M ^a   Sherlock, J P ^b  

^a LOUGHBOROUGH UNIVERSITY   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Mixing time; Pharmaceuticals; Power number; Solid liquid mixing; Stirred tank reactor

Indexed keywords

BLENDING; COMPUTATIONAL FLUID DYNAMICS; FLOW OF FLUIDS; MIXING; NUMBER THEORY;

CONICAL-BASED VESSEL; MIXING TIME; POWER NUMBER; SOLID-LIQUID MIXING; STIRRED TANK REACTOR;

CHEMICAL REACTORS;

BLENDING; CHEMICAL REACTORS; COMPUTATIONAL FLUID DYNAMICS; FLOW OF FLUIDS; MIXING; NUMBER THEORY;

EID: 34547808446     PISSN: 02638762     EISSN: None     Source Type: Journal    
DOI: 10.1205/cherd07002     Document Type: Article

References (19)

1. Armenante, P.M. and Nagamine, E.U., 1998, Effect of low off-bottom clearance on the min. agitation speed for complete suspension of solids in stirred tanks, Chem Eng Sci, 53: 1757-1775.
2. Campolo, M., Paglianti, A. and Soldati, A., 2002, Fluid dynamic efficiency and scale-up of a retreated blade impeller CSTRs, Ind Eng Chem Res, 41: 164-172.
3. Campolo, M. and Soldati, A., 2002, Appraisal and fluid dynamic efficiency of retreated-blade and turbofoil impellers in industrial-size CSTRs, Ind Eng Chem Res, 41: 1370-1377.
4. Dickey, D.S., Bittorf, K.J., Ramsey, C.J. and Johnson, K.E., 2004, Understand flow patterns in glass-lined reactors, Chem Eng Progress Magazine, 21-25.
5. Habib, M., 2005, Mixing in conical based pharmaceutical reactors equipped with retreat curve impellers, MSc thesis, Department of Chemical Engineering, Loughborough University, UK.
6. Haque, J.N., Mahmud, T., Roberts, K.J. and Rhodes, D., 2006, Modeling turbulent flows with free-surface in unbaffled agitated vessels, Ind Eng Chem Res, 45(8): 2881-2891.
7. Khan, F.R., Rielly, C.D. and Hargrave, G.K., 2004, A multi-block approach to obtain angle-resolved PIV measurements of the mean flow and turbulence fields in a stirred vessel, Chem Eng Technol, 27: 264-269.
8. Kumaresan, T., Nere, N.K. and Joshi, J.B., 2005, Effect of internals on the flow pattern and mixing in stirred tanks, Ind Eng Chem Res, 44: 9951-9961.
9. Li, M., White, G. and Wilkinson, D., 2004, LDA measurements and CFD modelling of a stirred vessel with a retreat curve impeller, Ind Eng Chem Res, 43: 6534-6547.
10. Li, M., White, G., Wilkinson, D. and Roberts, K.J., 2005, Scale up study of retreat curve impeller stirred tank using LDA and CFD, Chem Eng J, 108(1-2): 81-90.
11. Myers, K.J., Reeder, M.F. and Fasano, J.B., 2002, Optimize mixing by using the proper baffles, Chem Eng Progress Magazine, 42-47.
12. Myers, K.J., Fasano, J.B. and Corpstein, R.R., 1994, The influence of solid properties on the just-suspended agitation requirements of pitched-blade and high-efficiency impellers, Can J Chem Eng, 72(4): 745-748.
13. Nagata, S., 1975, Mixing: Principles and Applications (Halstead Press, Tokyo, Japan).
14. Paul, E.L., Atiemo-Obeng, V.A. and Kresta, S.M., 2004, Handbook of Industrial Mixing (Wiley Interscience, John Wiley & Son, Inc., Hoboken, New Jersey, USA).
15. Ricard, F., Brechtelsbauer, C., Xu, X.Y. and Lawrence, C.J., 2005, Monitoring of multi-phase pharmaceutical processes using electrical resistance tomography, Chem Eng Res Des, 83(A7): 794-805.
16. Rielly, C.D. and Britter, R.E., 1985, Mixing of passive tracers in stirred tanks, 5th Eur Conf on Mixing, Wurzburg, FRG, BHRA Fluid Eng., 365-375.
17. Rielly, C.D. and Marquis, A.J., 2001, A particle's eye view of crystallizer fluid mechanics, Chem Eng Sci, 56: 2475-2493.
18. Ruszkowski, S., 1994, A rational method for measuring blending performance and comparison of different impeller types, 8th Eur Conf on Mixing, 283-291, Inst Chem Engrs, Rugby, UK.
19. Zwietering, T.N., 1958, Suspending of solid particles in liquid by agitators, Chem Eng Sci, 8: 244-253.