Plasma adrenocorticotropin, cortisol, and adrenocorticotropin/cortisol ratios in septic and normal-term foals

Journal of Veterinary Internal Medicine

Volumn 21, Issue 4, 2007, Pages 791-796

  Gold, J R ^a,d   Divers, T J ^a   Barton, M H ^b   Lamb, S V ^a   Place, N J ^a   Mohammed, H O ^a   Bain, F T ^c  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c Haygard Equine Medical Institute   (United States)

^d Bend Equine Medical Center   (United States)

Author keywords

Corticosteroids; Equine; Hypothalamic pituitary adrenal axis; Neonates; Relative adrenal insufficiency

Indexed keywords

CORTICOTROPIN; HYDROCORTISONE;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; HORSE; HORSE DISEASE; NEWBORN; SEPSIS;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; ANIMALS, NEWBORN; HORSE DISEASES; HORSES; HYDROCORTISONE; SEPSIS;

ANIMALIA; EQUIDAE;

EID: 34547798555     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1892/0891-6640(2007)21[791:PACACR]2.0.CO;2     Document Type: Article

References (28)

1. McCann SM, Antunes-Rodrigues J, Franci CR, et al. Role of the hypothalamic pituitary adrenal axis in the control of the response to stress and infection. Braz J Med Biol Res 2000;33:1121-1131.
2. Manglik S, Flores E, Lubarsky L, et al. Glucocorticoid insufficiency in patients who present to the hospital with severe sepsis: A prospective clinical trial. Crit Care Med 2003;31:1668-1674.
3. Marik PE, Gayowski T, Starzi TE, et al. The hepatoadrenal syndrome: A common yet unrecognized clinical condition. Crit Care Med 2005;33:1254-1258.
4. Balk FA. Steroids for septic shock back from the dead. Chest 2003;123:490S-499S.
5. Siraux V, DeBacker D, Yalavatti G, et al. Relative adrenal insufficiency in patients with septic shock: comparison of low-dose and conventional corticotropin tests. Crit Care Med 2005;33:2479-2486.
6. Prigent H, Maxime V, Annane D. Critical review: Corticotherapy in Sepsis. Crit Care Med 2003;8:122-129.
7. Gonalez H, Nardi O, Annane D. Relative adrenal failure in the ICU: An identifiable problem requiring treatment. Crit Care Clin 2006;22:105-118.
8. Morel J, Venet C, Donati Y, et al. Adrenal axis does not appear to be associated with hemodynamic improvement in septic shock patients systematically receiving glucocorticoid therapy. Intensive Care Med 2006;32:1184-1190.
9. Pizarro CF, Troster EJ, Damiani D, et al. Absolute and relative adrenal insufficiency in children with septic shock. Crit., Care Med 2005;33:855-859.
10. Soliman AT, Taman KH, Rizk MM, et al. Circulating adrenocorticotrophic hormone (ACTH) and cortisol concentrations in normal, appropriate-for- gestational-age newborns versus those with sepsis and respiratory distress: Cortisol response to low dose and standard dose ACTH tests. Metabolism 2004;53:209-214.
11. Johnson KL. The hypothalamic-pituitary-adrenal axis in critical illness, AACN Clin Issues 2006;17:39-49.
12. Rossdale P, Silver M, Comline RS, et al. Plasma cortisol in the foal during the late fetal and early neonatal period. Res Vet Sci 1973;15:395-397.
13. Silver M, Ousey., JC, Dudan FE, et al. Studies on equine prematurity 2: Post natal adrenocortical activity in relation to plasma adrenocorticotrophic hormone and catecholamine levels in term and premature foals. Equine Vet J 1984;16:278-286.
14. 3) and Cortisol concentrations in foals from birth to 28 days of age. Equine Vet J 1993;25:237-239.
15. Eiler H, Goble D, Oliver J. Adrenal gland function in the horse; effects of cosyntropin (synthetic) and corticotropin (natural) stimulation. Am J Vet Res 1979;40:724-726.
16. Hoffsis., GF., Murdick PW, Tharp VL, et al. Plasma concentrations of cortisol and corticosterone in the normal horse. Am J Vet Res 1970;31:1379-1387.
17. Couetil L, Paradis MR, Knoll J. Plasma adrenocorticotropin concentration in healthy horses and in horses with clinical signs of hyperadrenocorticism. J Vet Intern Med 1996;10:1-6.
18. Brewer BD, Koterba AM. Development of a scoring system for the early diagnosis of equine neonatal sepsis. Equine Vet J 1988;20:18-20.
19. Perkins GA, Lamb SV, Erb HN, Schanbacher B, et al. Plasma adrenocorticotropin (ACTH) concentrations and clinical response in horses treated for equine Cushing's disease with cyproheptadine or pergolide. Equine Vet J. 2002;34:679-683.
20. Reimers TJ, Salerno VJ, Lamb SV. Validation and application of solid-phase chemiluminescent immunoassays for diagnosis of endocrine diseases in animals. Comparative Haematology International 1996;6:170-175.
21. Alia P, Villabona C, Gimenez O, et al. Profile, mean residence time of ACTH and Cortisol responses after low and standard ACTH tests in healthy volunteers. Clin Endocrinol 2006;65:346-351.
22. Rai R, Cohen J, Venkatesh B. Assessment of adrenocortical function in the critically ill. Critical Care Resus 2004;6:123-129.
23. Venkatesh B, Mortimer RH, Couchman B, et al. Evaluation of random plasma cortisol and the low dose corticotropin test as indicators of adrenal secretory capacity in critically ill patients: A prospective study, Anaesth Intensive Care 2005;33:201-209.
24. Widmer IE, Puder JJ, Konig C, et al. Cortisol response in relation to the severity of stress and illness. J Clin Endocrinol Metab 2005;90:4973-4974.
25. Fernandez E, Schrader R, Watterberg K. Relevance of low cortisol values in term and near-term infants with vasopressorresistant hypotension. J Perinatol 2005;25:114-118.
26. Ng PC, Lee CH, Bnur FL, et al. A double-blind, randomized, controlled study of a "stress dose" of hydrocortisone for rescue treatment of refractory hypotension in preterm Infants. Pediatrics 2006;117:516-518.
27. Marik PE, Zaloga GP. Adrenal insufficiency during septic shock. Crit Care Med 2003;31:141-145.
28. Couetil LL, Hoffman AM. Adrenal insufficiency in a neonatal foal. J Am Vet Med Assoc 1998;212:1594-1596.