Chemopreventive effects of lupulone, a hop β-acid, on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis

Carcinogenesis

Volumn 28, Issue 7, 2007, Pages 1575-1581

  Lamy, Virginie ^a,b,c   Roussi, Stamatiki ^a,b,c   Chaabi, Mehdi ^b,d   Gossé, Francine ^a,b,c   Schall, Nicolas ^a,b,c   Lobstein, Annelise ^b,d   Raul, Francis ^a,b,c  

^a INSERM   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c IRCAD   (France)

^d CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AZOXYMETHANE; DEATH RECEPTOR 4; DEATH RECEPTOR 5; FAS ANTIGEN; FAS LIGAND; LUPULON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CANCER PREVENTION; CHEMOPROPHYLAXIS; COLON CARCINOGENESIS; COLON CARCINOMA; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EXPOSURE; HUMAN; HUMAN CELL; LOW DRUG DOSE; MALE; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE; UPREGULATION;

ANIMALS; ANTICARCINOGENIC AGENTS; ANTIGENS, CD95; APOPTOSIS; AZOXYMETHANE; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; FAS LIGAND PROTEIN; HUMANS; INTESTINAL MUCOSA; MALE; MITOCHONDRIAL MEMBRANES; NEOPLASM METASTASIS; PERMEABILITY; PLANT PREPARATIONS; RATS; RATS, WISTAR; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; TERPENES;

EID: 34547779516     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgm080     Document Type: Article

References (37)

1. Verzele,M. et al. (1978) High-performance liquid chromatography of hop bitter substances. J. Chromatogr., 166, 320-326.
2. Gerhauser,C. (2005) Beer constituents as potential cancer chemopreventive agents. Eur. J. Cancer, 41, 1941-1954.
3. Honma,Y. et al. (1998) Induction of differentiation of myelogenous leukemia cells by humulone, a bitter in the hop. Leuk. Res., 22 605-610.
4. Tobe,H. et al. (1997) Apoptosis to HL-60 by humulone. Biosci. Biotechnol. Biochem., 61, 1027-1029.
5. Chen,W.J. et al. (2004) Mechanisms of cancer chemoprevention by hop bitter acids (beer aroma) through induction of apoptosis mediated by Fas and caspase cascades. J. Agric. Food Chem., 52, 55-64.
6. Tagashira,M. et al. (1995) Antioxidative activity of hop bitter acids and their analogues. Biosci. Biotechnol. Biochem., 59, 740-742.
7. Zhao,F. et al. (2003) Inhibitors of nitric oxide production from hops (Humulus lupulus L.). Biol. Pharm. Bull., 26, 61-65.
8. Yamamoto,K. et al. (2002) Suppression of cyclooxygenase-2 gene transcription by humulon of beer hop extract studied with reference to glucocorticoid. Adv. Exp. Med. Biol., 507, 73-17.
9. Nozawa,H. et al. (2005) Dietary supplement of isohumulones inhibits the formation of aberrant crypt foci with a concomitant decrease in prostaglandin E2 level in rat colon. Mol. Nutr. Food Res. 49, 772-778.
10. Shimamura,M. et al. (2001) Inhibition of angiogenesis by humulone, a bitter acid from beer hop. Biochem. Biophys. Res. Commun., 289, 220-224.
11. Coelho,D. et al. (2000) Caspase-3-like activity determines the type of cell death following ionizing radiation in MOLT-4 human leukaemia cells. Br. J. Cancer, 83, 642-4649.
12. Novo,D. et al. (1999) Accurate flow cytometric membrane potential measurement in bacteria using diethyloxacarbocyanine and a ratiometric technique. Cytometry, 35, 55-63.
13. Fischer,B. et al. (2005) Fast neutros-induced apoptosis is Fas-independent in lymphoblastoid cells. Biochem. Biophys. Res. Commun., 334, 533-542.
14. Kroemer,G. et al. (2005) Caspase-independent cell death. Nat. Med., 11, 725-730.
15. Sharpe,J.C. et al. (2004) Control of mitochondrial permeability by Bc1-2 family members. Biochim. Biophys. Acta, 1644, 107-113.
16. Green,D.R. et al. (2004) The pathophysiology of mitochondrial cell death. Science, 305, 626-629.
17. Korsmeyer,S.J. et al. (1995) Reactive oxygen species and the regulation of cell death by the Bc1-2 gene family. Biochim. Biophys. Acta, 1271, 63-66.
18. Ozoren,N. et al. (2003) Cell surface death receptor signalling in normal and cancer cells. Semin. Cancer Biol., 13, 135-147.
19. Kimberley,F.C. et al. (2004) Following a TRAIL: Update on a ligand and its five receptors. Cell Res., 14, 359-372.
20. Kim,R. et al. (2004) Regulation and interplay of apoptotic and non-apoptotic cell death. J. Pathol., 208, 319-326.
21. Antonsson,B. (2004) Mitochondria and the Bc1-2 family proteins in apoptosis signaling pathways. Mol. Cell. Biochem., 256, 141-155.
22. Benimetskaya,L. et al. (2004) Relative Bc1-2 independence of drug-induced cytotoxicity and resistance in 518A2 melanoma cells. Clin. Cancer Res., 10, 8371-8379.
23. Roussi,S. et al. (2006) Mitochondrial perturbation, oxidative-stress and lysosomal destabilization are involved in 7beta-hydroxysitosterol and 7beta-hydroxycholesterol triggered apoptosis in human colon cancer cells. Apoptosis, 12, 87-96.
24. Gupta,S. (2001) Molecular steps of death receptor and mitochondrial pathways of apoptosis. Life Sci., 69, 2957-2964.
25. Suliman,A. et al. (2001) Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways. Oncogene, 20, 2122-2133.
26. Srivastava,R.K. (2001) TRAIL/Apo-2L: Mechanisms and clinipal applications in cancer. Neoplasia, 3, 535-546.
27. Vaculova,A. et al. (2006) Different modulation of TRAIL-induced apoptosis by inhibition of pro-survival pathways in TRAII-sensitive and TRAIL-resistant colon cancer cells. FEBS Lett., 580, 6565-6569.
28. Wang,S. et al. (2003) TRAIL and apoptosis induction by TNF-family death receptors. Oncegene, 22, 8628-8633.
29. Kazhdan, I. et al. (2004) Death receptor 4 (DR4) efficiently kills breast cancer cells irrespective of their sensitivity to tumor necrosis factor-related apoptasis-inducing ligand (TRAIL). Cancer Gene Ther. 11, 691-698.
30. Corpet,D.E. et al. (2005) How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and humans. Eur. J. Cancer, 41, 1911-1922.
31. Reddy,B.S. et al. (2005) Chemoprophylaxis of colon cancer. Curr. Gastroenterol. Rep., 7, 389-395.
32. Rodgers,A.E. et al. (1985) Rodent model for carcinoma of the colon. Dig. Dis. Sci., 66, 87S-102S.
33. Ma,Q.Y. et al. (2002) Variability of cell proliferation in the proximal and distal colon of normal rats and rats with dimethylhydrazine induced carcinogenesis. World J. Gastroenterol., 8, 847-852.
34. Toribara,N.W. (1994) Colorectal cancer. A new look at an old problem. West. J. Med., 161, 487-494.
35. Jemal,A. et al. (2004) Cancer statistics, 2004. CA Cancer J. Clin., 54, 8-29.
36. Macejova,D. et al. (2001) Chemically induced cardinogenesis: A comparison of 1-methyl-1-nitrosurea, 7,12-dimethylbenzanthracene,diethyl-nitroso-amine and azoxymethane models (minireview): Endocr. Regul., 35, 53-59.
37. Chappel,C.I. et al. (1999) Subchronic toxicity study of tetrahydroisohumulone and hexahydroisohumulone in the Beagle dog. Food Chem. Toxicol., 36, 915-922.