Inhibition of reactive nitrogen species in vitro and ex vivo by trypsin inhibitor from sweet potato 'Tainong 57' storage roots

Journal of Agricultural and Food Chemistry

Volumn 55, Issue 15, 2007, Pages 6000-6006

  Huang, Guan Jhong ^a   Sheu, Ming Jyh ^b   Chen, Hsien Jung ^c   Chang, Yuan Shiun ^a   Lin, Yaw Huei ^d  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHINESE CULTURE UNIVERSITY   (Taiwan)

^d INSTITUTE OF PLANT AND MICROBIAL BIOLOGY   (Taiwan)

Author keywords

Nitric oxide; Peroxynitrite; Superoxide; Sweet potato; Trypsin inhibitor

Indexed keywords

PEROXYNITROUS ACID; REACTIVE NITROGEN SPECIES; SCAVENGER; TRYPSIN INHIBITOR;

ANIMAL; ARTICLE; CELL LINE; CHEMISTRY; DRUG ANTAGONISM; MACROPHAGE; MOUSE; PLANT ROOT; SWEET POTATO;

ANIMALS; CELL LINE; FREE RADICAL SCAVENGERS; IPOMOEA BATATAS; MACROPHAGES; MICE; PEROXYNITROUS ACID; PLANT ROOTS; REACTIVE NITROGEN SPECIES; TRYPSIN INHIBITORS;

BOVINAE; IPOMOEA BATATAS;

EID: 34547755944     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf0701786     Document Type: Article

References (35)

1. Marcocci, L.; Maguire, J. J.; Droy-Lefaix, M. T.; Packer, L. The nitric oxide-scavenging properties of Ginkgo biloba extract EGb 761. Biochem. Biophys. Res. Commun. 1994, 15, 748-755.
2. Marcocci, L.; Packer, L.; Droy-Lefaix, M. T., et al. Antioxidant action of Ginkgo biloba extract EGB 761. Methods Enzymol. 1994, 234, 462-475.
3. Wink, D. A.; Kasprzak, K. S.; Maragos, C. M., et al. DNA deaminating ability and genotoxicity of nitric oxide and its progenitors. Science 1991, 254, 1001-1003.
4. Balavoine, G. G.; Geletii, Y. V. Peroxynitrite scavenging by different antioxidants. Part I: convenient assay. Nitric Oxide 1999, 3, 40-54.
5. Patel, R. P.; McAndrew, J.; Sellak, H.; White, C. R.; Jo, H.; Freeman, B. A.; Darley-Usmar, V. Biological aspects of reactive nitrogen species (review). Biochim. Biophys. Acta 1999, 1411, 385-400.
6. Briviba, K.; Klotz, L.-O.; Sies, H. Defenses against peroxynitrite. Methods Enzymol. 1999, 301, 391-411.
7. Darley-Usmar, V.; Halliwell, B. Blood radicals: reactive nitrogen species, reactive oxygen species, transition metal ions, and the vascular system (review). Pharm. Res. 1996, 13, 649-662.
8. Minetti, M.; Mallozzi, C.; Di Stasi, AM.; Peroxynitrite activates kinases of the src family and upregulates tyrosine phosphorylation signaling. Free Radic. Biol. Med. 2002, 33 (6), 744-754.
9. Menconi, M. J.; Unno, N.; Smith, M.; Aguirre, D. E.; Fink, M. P. Nitric oxide donor-induced hyperpermeability of cultured intestinal epithelial monolayers: role of superoxide radical, hydroxyl radical, and peroxynitrite. Biochim. Biophys. Acta 1998, 1425, 189-203.
10. Cuzzocrea, S.; Tan, D. X.; Costantino, G.; Mazzon, E.; Caputi, A. P.; Reiter, R. J. The protective role of endogenous melatonin in carrageenan-induced pleurisy in the rat. FASEB J. 1999, 13, 1930-1938.
11. Zou, Y.; Kim, A. R.; Kim, J. E.; Ceol, J. S.; Chung, H. Y. Peroxynitrite scavenging activity of sinapic acid (3,5-dimethoxy-4-hydroxycinnamic acid) isolated from Brassica juncea. J. Agric. Food Chem. 2002, 50, 5884-5890.
12. Sohonie, K.; Bhandarker, A. P. Trypsin inhibitors in Indian foodstuffs: I. Inhibitors in vegetables. J. Sci. Ind. Res. 1954, 13B, 500-503.
13. Lin, Y. H.; Chen, H. L. Level and heat stability of trypsin inhibitor activity among sweet potato (Ipomoea batatas Lam.) varieties. Bot. Bull. Acad. Sin. 1980, 21, 1-13.
14. Maeshima, M.; Sasaki, T.; Asahi, T. Characterization of major proteins in sweet potato tuberous roots. Phytochemistry 1985, 24, 1899-1902.
15. Lin, Y. H. Trypsin inhibitors of sweet potato: review and prospect. In Recent Advances in Botany; Hsing, Y. I., Chou, C. H., Eds.; Academia Sinica Monograph Series 13; Taipei, Taiwan, 1993; pp 179-185.
16. Yeh, K. W.; Chen, J. C.; Lin, M. I.; Chen, Y. M.; Lin, C. Y. Functional activity of sporarnin from sweet potato (Ipomoea batatas Lam.): a tuber storage protein with trypsin inhibitory activity. Plant Mol. Biol. 1997, 33, 565-570.
17. Caj, D.; Thuray T.; Tian, Y.; Lange, T.; Yeh, K. W.; Jung, C. Sporamin-mediated resistance to beet cyst nematodes (Heterodera schachtii Schm.) is dependent on trypsin inhibitory activity in sugar beet (Beta vulgaris L.) hairy roots. Plant Mol. Biol. 2003, 51, 839-849.
18. Hou, W. C.; Chen, Y. C.; Chen, H. J.; Lin, Y. H.; Yang, L. L.; Lee, M. H. Antioxidant activities of trypsin inhibitor, a 33 kDa root storage protein of sweet potato (Ipomoea batatas (L.) Lam. cv. Tainong 57). J. Agric. Food Chem. 2001, 49, 2978-2981.
19. Huang, G. J.; Sheu, M. J.; Chen, H. J.; Chang, Y. S.; Lin, Y. H. Induced apoptosis and G2/M cell cycle arrest by trypsin inhibitor from sweet potato (Ipomoea batatas (L.) Lam 'Tainong 57') storage roots in NB4 premyelocytic leukemia cells. J. Agric. Food Chem. 2007, 55, 2548-2553.
20. Nikishimi, M.; Rao, N.; Yagi, K. The occurrence of superoxide anion in the reaction of reduced phenazine methosulphate and molecular oxygen. Biochem. Biophys. Res. Commun. 1972, 46, 849-854.
21. Huang, D. J.; Chen, H. J.; Hou, W. C.; Chen, T. E.; Lin, Y. H. Isolation and characterization of cysteine proteinase cDNA from sweet potato (Ipomoea batatas [L.] Lam 'Tainong 57') storage roots. Plant Sci. 2005, 169, 423-431.
22. Huang, D. J.; Chen, H. J.; Hou, W. C.; Chen, T. E.; Lin, Y. H. In vitro reduction of trypsin inhibitor by purified NADPH/thioredoxin system from sprouts of sweet potato (Ipomoea batatas (L) Lam.) storage roots. Plant Sci. 2004, 166, 435-441.
23. Beauchamp, C.; Fridovich, I. Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. Anal. Biochem. 1971, 44, 276-287.
24. Kooy, N. W.; Royall, J. A.; Ischiropoulos, H.; Beckman, J. S. Peroxynitrite-mediated, oxidation of dihydrorhodamine 123. Free Radical Biol. Med. 1994, 16, 149-156.
25. Huang, D. J.; Lin, C. D.; Chen, H. J.; Lin, Y. H. Antioxidant and antiproliferative activities of sweet potato (Ipomoea batatas (L.) Lam. 'Tainong 57') constituents. Bot. Bull. Acad. Sin. 2004, 45, 179-186.
26. Halliwell, B.; Gutteridge, J. M. C. Free Radicals in Biology and Medicine, 3rd ed.; Oxford University Press: Oxford, U.K., 1999; pp 60-67.
27. Sies, H.; Klotz, L. O.; Sharov, V. S.; Assmann, A.; Briviba, K. Protection against peroxynitrite by selenoproteins. Z. Naturforsch. 1998, 53, 228-232.
28. Afzal, M.; Al-Hadidi, D.; Menon, M.; Pesek, J.; Dhami, M. S. Ginger: an ethnomedical, chemical and pharmacological review. Drug Metab. Drug Interact. 2001, 18, 159-190.
29. Aeschbach, R.; Loliger, J.; Scott, B. C.; Murcia, A.; Butler, J.; Halliwell, B.; Aruoma, O. I. Antioxidant actions of thymol, carvacrol, 6-gingerol, zingerone and hydroxytyrosol. Food Chem. Toxicol. 1994, 32, 31-36.
30. Pannala, A.; Razaq, R.; Halliwell, B.; Singh, S.; Rice-Evans, C. A. Inhibition of peroxynitrite dependent nitration by hydroxycinnamates: nitration or electron donation? Free Radical Biol. Med. 1998, 24, 594-606.
31. Li, X.; De Sarno, P.; Song, L.; Beckman, J. S.; Jope, R. S. Peroxynitrite modulates tyrosine phosphorylation and phosphoinositide signaling in human neuroblastoma SH-SY5Y cells: attenuated effects in human 1321N1 astrocytoma cells. Biochem. J. 1998, 331, 599-606.
32. MacMillan-Crow, L. A.; Thompson, J. A. Tyrosine modifications and inactivation of active site manganese superoxide dismutase mutant (Y34F) by peroxynitrite. Arch. Biochem. Biophys. 1999, 366, 82-88.
33. 2+-ATPase in skeletal muscle. Biochem. J. 1999, 340, 657-669.
34. Vaziri, N. D.; Liang, K.; Ding, Y. Increased nitric oxide inactivation by reactive oxygen species in lead-induced hypertension. Kidney Int. 1999, 56, 1492-1498.
35. Roberts, C. K.; Vaziri, N. D.; Wang, X. Q.; Barnard, R. J. Enhanced NO inactivation and hypertension induced by a high fat, refined-carbohydrate diet. Hypertension 2000, 36, 423-429.