Null mutation for Macrophage Migration Inhibitory Factor (MIF) is associated with less aggressive bladder cancer in mice

BMC Cancer

Volumn 7, Issue , 2007, Pages

  Taylor III, John A ^a   Kuchel, George A ^a   Hegde, Poornima ^a   Voznesensky, Olga S ^a   Claffey, Kevin ^a   Tsimikas, John ^a   Leng, Lin ^b   Bucala, Richard ^b   Pilbeam, Carol ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; EOSIN; HEMATOXYLIN; MACROPHAGE MIGRATION INHIBITION FACTOR; MESSENGER RNA; N BUTYL N (4 HYDROXYBUTYL)NITROSAMINE; ISOMERASE; MIF PROTEIN, MOUSE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CANCER; CANCER GRADING; CANCER GROWTH; CANCER INVASION; CANCER STAGING; CONTROLLED STUDY; CYTOPLASM; GENE MUTATION; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; STROMA; UROTHELIUM; VASCULARIZATION; WILD TYPE; ANIMAL; BLADDER TUMOR; CHEMICALLY INDUCED DISORDER; DISEASE COURSE; GENE EXPRESSION; GENETICS; MOUSE MUTANT; MUTATION; PATHOLOGY;

ANIMALS; BUTYLHYDROXYBUTYLNITROSAMINE; DISEASE PROGRESSION; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INTRAMOLECULAR OXIDOREDUCTASES; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MALE; MICE; MICE, KNOCKOUT; MUTATION; NEOPLASM INVASIVENESS; NEOPLASM STAGING; RNA, MESSENGER; URINARY BLADDER NEOPLASMS;

EID: 34547737524     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-7-135     Document Type: Article

References (24)

1. Cancer Facts and Figures, American Cancer Society 2007
2. Fingerle-Rowson G Petrenko O Metz CN Forsthuber TG Mitchell R Huss R Moll U Muller W Bucala R The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting Proc Natl Acad Sci U S A 2003 100 9354-9359 170922 12878730 10.1073/pnas.1533295100
3. Petrenko O Moll UM Macrophage migration inhibitory factor MIF interferes with the Rb-E2F pathway Mol Cell 2005 17 225-236 10.1016/ j.molcel.2004.11.052 15664192
4. Tomiyasu M Yoshino I Suemitsu R Okamoto T Sugimachi K Quantification of macrophage migration inhibitory factor mRNA expression in non-small cell lung cancer tissues and its clinical significance Clin Cancer Res 2002 8 3755-3760 12473586
5. Bando H Matsumoto G Bando M Muta M Ogawa T Funata N Nishihira J Koike M Toi M Expression of macrophage migration inhibitory factor in human breast cancer: Association with nodal spread Jpn J Cancer Res 2002 93 389-396 11985788
6. Meyer-Siegler K Hudson PB Enhanced expression of macrophage migration inhibitory factor in prostatic adenocarcinoma metastases Urology 1996 48 448-452 10.1016/S0090-4295(96)00207-5 8804500
7. Bozza M Satoskar AR Lin G Lu B Humbles AA Gerard C David JR Targeted disruption of migration inhibitory factor gene reveals its critical role in sepsis J Exp Med 1999 189 341-346 10.1084/jem.189.2.341 9892616
8. Detre S Saclani Jotti G Dowsett M A "quickscore" method for immunohistochemical semiquantitation: Validation for oestrogen receptor in breast carcinomas J Clin Pathol 1995 48 876-878 502883 7490328 10.1136/jcp.48.9.876
9. Weidner N Semple JP Welch WR Folkman J Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma N Engl J Med 1991 324 1-8 1701519
10. Meyer-Siegler KL Leifheit EC Vera PL Inhibition of macrophage migration inhibitory factor decreases proliferation and cytokine expression in bladder cancer cells BMC Cancer 2004 4 34 481073 15248897 10.1186/ 1471-2407-4-34
11. David JR Delayed hypersensitivity in vitro: Its mediation by cell-free substances formed by lymphoid cell-antigen interaction Proc Natl Acad Sci U S A 1966 56 72-77 285677 5229858 10.1073/pnas.56.1.72
12. Calandra T Bucala R Macrophage migration inhibitory factor (MIF): A glucocorticoid counter-regulator within the immune system Crit Rev Immunol 1997 17 77-88 9034724
13. Hudson JD Shoaibi MA Maestro R Carnero A Hannon GJ Beach DH A proinflammatory cytokine inhibits p53 tumor suppressor activity J Exp Med 1999 190 1375-1382 10.1084/jem.190.10.1375 10562313
14. Petrenko O Fingerle-Rowson G Peng T Mitchell RA Metz CN Macrophage migration inhibitory factor deficiency is associated with altered cell growth and reduced susceptibility to Ras-mediated transformation J Biol Chem 2003 278 11078-11085 10.1074/jbc.M211985200 12538581
15. Lue H Thiele M Franz J Dahl E Speckgens S Leng L Fingerle-Rowson G Bucala R Luscher B Bernhagen J Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity Oncogene 2007 17310986
16. Ren Y Chan HM Fan J Xie Y Chen YX Li W Jiang GP Liu Q Meinhardt A Tam PK Inhibition of tumor growth and metastasis in vitro and in vivo by targeting macrophage migration inhibitory factor in human neuroblastoma Oncogene 2006 25 25 3501-3508 10.1038/sj.onc.1209395 16449971
17. Hagemann T Wilson J Kulbe H Li NF Leinster DA Charles K Klemm F Pukrop T Binder C Balkwill FR Macrophages induce invasiveness of epithelial cancer cells via NF-kappaB and JNK J Immunol 2005 175 1197-1205 16002723
18. Meyer-Siegler KL Vera PL Substance P induced release of macrophage migration inhibitory factor from rat bladder epithelium J Urol 2004 171 1698-1703 10.1097/01.ju.0000115883.49365.1a 15017269
19. Onodera S Nishihira J Iwabuchi K Koyama Y Yoshida K Tanaka S Minami A Macrophage migration inhibitory factor up-regulates matrix metalloproteinase-9 and -13 in rat osteoblasts. Relevance to intracellular signaling pathways J Biol Chem 2002 277 7865-7874 10.1074/ jbc.M106020200 11751895
20. Onodera S Kaneda K Mizue Y Koyama Y Fujinaga M Nishihira J Macrophage migration inhibitory factor up-regulates expression of matrix metalloproteinases in synovial fibroblasts of rheumatoid arthritis J Biol Chem 2000 275 444-450 10.1074/jbc.275.1.444 10617637
21. Taylor JA Zhu Q Irwin B Maghaydah Y Tsimikas J Pilbeam C Leng L Bucala R Kuchel GA Null mutation in macrophage migration inhibitory factor prevents muscle cell loss and fibrosis in partial bladder outlet obstruction Am J Physiol Renal Physiol 2006 291 F1343-53 10.1152/ ajprenal.00144.2006 16835407
22. Charlesworth PJ Harris AL Mechanisms of disease: Angiogenesis in urologic malignancies Nat Clin Pract Urol 2006 3 157-169 10.1038/ ncpuro0434 16528288
23. Kamimura A Kamachi M Nishihira J Ogura S Isobe H Dosaka-Akita H Ogata A Shindoh M Ohbuchi T Kawakami Y Intracellular distribution of macrophage migration inhibitory factor predicts the prognosis of patients with adenocarcinoma of the lung Cancer 2000 89 334-341 10.1002/ 1097-0142(20000715)89:2<334::AID-CNCR18>3.0.CO;2-N 10918163
24. Markert JM Fuller CM Gillespie GY Bubien JK McLean LA Hong RL Lee K Gullans SR Mapston TB Benos DJ Differential gene expression profiling in human brain tumors Physiol Genomics 2001 5 21-33 11161003