Upper cervical spinal cord cross-sectional area in relapsing remitting multiple sclerosis: Application of a new technique for measuring cross-sectional area on magnetic resonance images

Journal of Magnetic Resonance Imaging

Volumn 26, Issue 1, 2007, Pages 61-65

  Mann, Ranbir S ^a   Constantinescu, Cris S ^a   Tench, Christopher R ^a  

^a NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

Atrophy; Inflammation; MRI; Relapsing remitting multiple sclerosis; Spinal cord

Indexed keywords

ADULT; ARTICLE; BRAIN SIZE; CERVICAL SPINAL CORD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; IMAGE ANALYSIS; INFLAMMATION; MALE; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RADIOLOGICAL PARAMETERS; RECURRENT DISEASE; REMISSION; STATISTICAL ANALYSIS; TECHNIQUE;

ADULT; ATROPHY; CASE-CONTROL STUDIES; CERVICAL VERTEBRAE; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; INFLAMMATION; MAGNETIC RESONANCE IMAGING; MALE; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; SPINAL CORD; SPINAL CORD DISEASES; STATISTICS, NONPARAMETRIC;

EID: 34547732356     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.20959     Document Type: Article

References (30)

1. Trapp BD, Peterson J, Ransohoff RM, Rudick R, Mork S, Bo L. Axonal transection in the lesions of multiple sclerosis. N Engl J Med 1998;338:278-285.
2. Benedict RH, Carone DA, Bakshi R. Correlating brain atrophy with cognitive dysfunction, mood disturbances, and personality disorder in multiple sclerosis. J Neuroimaging 2004;14(3 Suppl):36S-45S.
3. Trip SA, Schlottmann PG, Jones SJ, et al. Optic nerve atrophy and retinal nerve fibre layer thinning following optic neuritis: evidence that axonal loss is a substrate of MRI-detected atrophy. Neuroimage 2006;31:286-293.
4. Miller DH, Barkhof F, Frank JA, Parker GJ, Thompson AJ. Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance. Brain 2002;125(Pt 8):1676-1695.
5. Lin X, Tench CR, Evangelou N, Jaspan T, Constantinescu CS. Measurement of spinal cord atrophy in multiple sclerosis. J Neuroimaging 2004;14(3 Suppl):20S-26S.
6. Bakshi R, Dandamudi VSR, Neema M, De C, Bermel RA. Measurement of brain and spinal cord atrophy by magnetic resonance imaging as a tool to monitor multiple sclerosis. J Neuroimaging 2005;15(4 Suppl):30S-45S.
7. Losseff NA, Webb SL, O'Rlordan JI, et al. Spinal cord atrophy and disability in multiple sclerosis. A new reproducible and sensitive MRI method with potential to monitor disease progression. Brain 1996;119(Pt 3):701-708.
8. Vaithianathar L, Tench CR, Morgan PS, Constantinescu CS. Magnetic resonance imaging of the cervical spinal cord in multiple sclerosis - a quantitative T1 relaxation time mapping approach. J Neurol 2003;250:307-315.
9. Lin X, Blumhardt LD, Constantinescu CS. The relationship of brain and cervical cord volume to disability in clinical subtypes of multiple sclerosis: a three-dimensional MRI study. Acta Neurol Scand 2003;108:401-406.
10. Lin X, Tench CR, Turner B, Blumhardt LD, Constantinescu CS. Spinal cord atrophy and disability in multiple sclerosis over four years: application of a reproducible automated technique in monitoring disease progression in a cohort of the interferon beta-1a (Rebif) treatment trial. J Neurol Neurosurg Psychiatry 2003;74:1090-1094.
11. Sailer M, Fischl B, Salat D, et al. Focal thinning of the cerebral cortex in multiple sclerosis. Brain 2003;126(Pt 8):1734-1744.
12. Dalton CM, Chard DT, Davies GR, et al. Early development of multiple sclerosis is associated with progressive grey matter atrophy in patients presenting with clinically isolated syndromes. Brain 2004;127(Pt 5):1101-1107.
13. Ge Y, Grossman RI, Udupa JK, Babb JS, Nyul LG, Kolson DL. Brain atrophy in relapsing-remitting multiple sclerosis: fractional volumetric analysis of gray matter and white matter. Radiology 2001;220:606-610.
14. Stevenson VL, Leary SM, Losseff NA, et al. Spinal cord atrophy and disability in MS: a longitudinal study. Neurology 1998;51:234-238.
15. Rashid W, Davies GR, Chard DT, et al. Upper cervical cord area in early relapsing-remitting multiple sclerosis: cross-sectional study of factors influencing cord size. J Magn Reson Imaging 2006;23:473-476.
16. Rashid W, Davies GR, Chard DT, et al. Increasing cord atrophy in early relapsing-remitting multiple sclerosis: a 3 year study. J Neurol Neurosurg Psychiatry 2006;77:51-55.
17. Ikuta F, Zimmerman HM. Distribution of plaques in seventy autopsy cases of multiple sclerosis in the United States. Neurology 1976;26(6 PT 2):26-28.
18. Brex PA, Leary SM, O'Riordan JI, et al. Measurement of spinal cord area in clinically isolated syndromes suggestive of multiple sclerosis. J Neurol Neurosurg Psychiatry 2001;70:544-547.
19. Hickman SJ, Coulon O, Parker GJ, et al. Application of a B-spline active surface technique to the measurement of cervical cord volume in multiple sclerosis from three-dimensional MR images. J Magn Reson Imaging 2003;18:368-371.
20. Tench CR, Morgan PS, Constantinescu CS. Measurement of cervical spinal cord cross-sectional area by MRI using edge detection and partial volume correction. J Magn Reson Imaging 2005;21:197-203.
21. Kidd D, Thorpe JW, Thompson AJ, et al. Spinal cord MRI using multi-array coils and fast spin echo. II. Findings in multiple scle-rosis. Neurology 1993;43:2632-2637.
22. Thorpe JW, Kidd D, Moseley IF, et al. Serial gadolinium-enhanced MRI of the brain and spinal cord in early relapsing-remitting multiple sclerosis. Neurology 1996;46:373-378.
23. Liu C, Edwards S, Gong Q, Roberts N, Blumhardt LD. Three dimensional MRI estimates of brain and spinal cord atrophy in multiple sclerosis. J Neurol Neurosurg Psychiatry 1999;66:323-330.
24. Bigler ED, Neeley ES, Miller MJ. et al. Cerebral volume loss, cognitive deficit and neuropsychological performance: comparative measures of brain atrophy: I. Dementia. J Int Neuropsychol Soc 2004;10:442-452.
25. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444-1452.
26. Eritaia J, Wood SJ, Stuart GW, et al. An optimized method for estimating intracranial volume from magnetic resonance images. Magn Reson Med 2000;44:973-977.
27. Jack Jr CR, Twomey CK, Zinsmeister AR, Sharbrough FW, Petersen RC, Cascino GD. Anterior temporal lobes and hippocampal formations: normative volumetric measurements from MR images in young adults. Radiology 1989;172:549-554.
28. Kameyama T, Hashizume Y, Ando T, Takahashi A. Morphometry of the normal cadaveric cervical spinal cord. Spine 1994;19:2077-2081.
29. Leary SM, Parker GJ, Stevenson VL, Barker GJ, Miller DH, Thompson AJ. Reproducibility of magnetic resonance imaging measurements of spinal cord atrophy: the role of quality assurance. Magn Reson Imaging 1999;17:773-776.
30. Filippi M, Rocca MA. MRI aspects of the "inflammatory phase" of multiple sclerosis. Neurol Sci 2003;(24 Suppl 5):S275-278.