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Volumn , Issue 23, 2007, Pages 3849-3858

Novel cyclic phosphate-linked oligosaccharides (CyPLOSs) covalently immobilized on solid supports for potential cation scavenging

Author keywords

31P NMR spectroscopy; Carbohydrates; Cyclic oligosaccharide analogues; Protecting groups lipophilicity; Solid phase synthesis

Indexed keywords


EID: 34547727255     PISSN: 1434193X     EISSN: 10990690     Source Type: Journal    
DOI: 10.1002/ejoc.200700203     Document Type: Article
Times cited : (9)

References (48)
  • 1
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  • 4
    • 0037013592 scopus 로고    scopus 로고
    • There is an impressive number of papers on modified cyclodextrins recognizing neutral or ionic guests; among others, see for example: c R. Heck, F. Dumarcay, A. Marsura, Chem. Eur. J. 2002, 8, 2438-2445;
    • There is an impressive number of papers on modified cyclodextrins recognizing neutral or ionic guests; among others, see for example: c) R. Heck, F. Dumarcay, A. Marsura, Chem. Eur. J. 2002, 8, 2438-2445;
  • 11
    • 34547754505 scopus 로고    scopus 로고
    • Water purification using cyclodextrins
    • Int. Patent WO 9818722, p. 21
    • c) B. Perly, C. Baudin, P. Gosselin, Water purification using cyclodextrins, Int. Patent WO 9818722, 1998, p. 21.
    • (1998)
    • Perly, B.1    Baudin, C.2    Gosselin, P.3
  • 17
    • 0001354595 scopus 로고    scopus 로고
    • a) A. R. Hedges, Chem. Rev. 1998, 98, 2035-2044;
    • (1998) Chem. Rev , vol.98 , pp. 2035-2044
    • Hedges, A.R.1
  • 42
    • 34547734988 scopus 로고    scopus 로고
    • In our previous paper, we first coupled the bifunctional linker 2-(3-chloro-4-hydroxyphenyl)acetic acid (10) with the 4-phosphoramidite sugar building block in solution, and then treated the resulting adduct with the TentaGel-NH2 solid support. Here this procedure was simplified by directly attaching bifunctional linker 10 to the resin by classical peptide coupling protocols, as also reported in ref.[13a, and by then treating phenolic resin 11 with sugar building block 9. On comparing the two routes for the synthesis of cyclic dimer 1, no significant differences were found either in yields or in purity of the released material
    • [13a], and by then treating phenolic resin 11 with sugar building block 9. On comparing the two routes for the synthesis of cyclic dimer 1, no significant differences were found either in yields or in purity of the released material.


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