In-vitro/in-vivo correlation of pulsatile drug release from press-coated tablet formulations: A pharmacoscintigraphic study in the beagle dog

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 67, Issue 2, 2007, Pages 515-523

  Ghimire, Manish ^a   McInnes, Fiona J ^a   Watson, David G ^a   Mullen, Alexander B ^a   Stevens, Howard N E ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Beagle dogs; IVIVC; Lag time; Pharmacoscintigraphy; Press coated tablets; Pulsatile release

Indexed keywords

GLYCEROL BEHENATE; HYDROXYPROPYLCELLULOSE; THEOPHYLLINE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CHRONOPHARMACOLOGY; CONTROLLED STUDY; CORRELATION ANALYSIS; DOG; DRUG BLOOD LEVEL; DRUG COATING; GAMMA SCINTIGRAPHY; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PHARMACOSCINTIGRAPHY; PRESS COATED TABLET; PULSATILE DRUG RELEASE; TABLET DISINTEGRATION; TABLET DISINTEGRATION TIME; TABLET FORMULATION;

ANIMALS; AREA UNDER CURVE; CELLULOSE; DELAYED-ACTION PREPARATIONS; DOGS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; GASTROINTESTINAL TRACT; PHARMACEUTICAL PREPARATIONS; RADIONUCLIDE IMAGING; SOLUBILITY; TABLETS; TECHNOLOGY, PHARMACEUTICAL; THEOPHYLLINE; TIME FACTORS;

EID: 34547697319     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2007.03.002     Document Type: Article

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