Effect of rifampicin pretreatment on the transport across rat intestine and oral pharmacokinetics of ornidazole in healthy human volunteers

Drug Metabolism and Drug Interactions

Volumn 22, Issue 2-3, 2007, Pages 151-163

  Shravan Kumar, Y ^a   Ramesh, S ^b   Madhusudan Rao, Y ^b   Paradkar, A R ^c  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

^b KAKATIYA UNIVERSITY   (India)

^c NONE

Author keywords

Cytochrome P450 enzymes; Drug interaction; Ornidazole; P glycoprotein; Pharmacokinetics; Rifampicin

Indexed keywords

BUTYRIC ACID; CYTOCHROME P450; GLYCOPROTEIN P; ORNI; ORNIDAZOLE; R CIN; RIFAMPICIN; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFECT; DRUG HALF LIFE; DRUG TRANSPORT; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MONOTHERAPY; NONHUMAN; NORMAL HUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SMALL INTESTINE;

ADMINISTRATION, ORAL; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIPROTOZOAL AGENTS; CYTOCHROME P-450 CYP3A; DRUG INTERACTIONS; HUMANS; MALE; ORNIDAZOLE; P-GLYCOPROTEINS; RATS; RATS, WISTAR; RIFAMPIN;

EID: 34547697170     PISSN: 07925077     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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