Cytochromes P450 catalyze oxidation of α,β-unsaturated aldehydes

Archives of Biochemistry and Biophysics

Volumn 464, Issue 2, 2007, Pages 187-196

  Amunom, Immaculate ^a,b   Stephens, Laura J ^a,b   Tamasi, Viola ^a,b   Cai, Jian ^a,b   Pierce Jr , William M ^a   Conklin, Daniel J ^a,b   Bhatnagar, Aruni ^a,b   Srivastava, S ^a,b   Martin, Martha V ^a,b   Guengerich, F Peter ^a,b   Prough, Russell A ^a,b  

^a University of Louisville School of Medicine   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

, Unsaturated aldehydes; 4 Hydroxynonenal; Anthracene 9 carboxaldehyde; Carboxylic acids; P450

Indexed keywords

4 HYDROXYNONENAL; 9 ANTHROIC ACID; ALDEHYDE; ALDEHYDE DEHYDROGENASE; CYANAMIDE; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2B4; CYTOCHROME P450 2B6; CYTOCHROME P450 2C29; CYTOCHROME P450 2E1; CYTOCHROME P450 2J2; CYTOCHROME P450 3A4; HEME; LIPID; MICONAZOLE; RECOMBINANT ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; THIOL; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME MECHANISM; ENZYME SUBSTRATE; HUMAN; LIPID PEROXIDATION; LIVER CELL; LIVER MICROSOME; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ALDEHYDES; ANIMALS; CATALYSIS; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; HEPATOCYTES; HUMANS; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED C57BL; MICROSOMES, LIVER; OXIDATION-REDUCTION; RATS; RATS, SPRAGUE-DAWLEY;

MURINAE; ORYCTOLAGUS CUNICULUS; RATTUS;

EID: 34547679627     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2007.05.019     Document Type: Article

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