-
1
-
-
0025127633
-
Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal
-
Esterbauer, H. and Cheeseman, K. H.:Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Method Enzymol., 186: 407-431 (1990).
-
(1990)
Method Enzymol.
, vol.186
, pp. 407-431
-
-
Esterbauer, H.1
Cheeseman, K.H.2
-
2
-
-
0019193338
-
Identîcation of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipid
-
Benedetti, A., Comporti, M. and Esterbauer, H.: Identîcation of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipid. Biochim. Biophys. Acta, 620: 261-296 (1980).
-
(1980)
Biochim. Biophys. Acta
, vol.620
, pp. 261-296
-
-
Benedetti, A.1
Comporti, M.2
Esterbauer, H.3
-
3
-
-
0021758483
-
Cytotoxic aldehydes originating from the peroxidation of liver microsomal lipid. Identîcation of 4, 5-dihydroxydecenal.
-
Benedetti, A., Comporti, M., Fulceri, R. and Esterbauer, H.: Cytotoxic aldehydes originating from the peroxidation of liver microsomal lipid. Identîcation of 4, 5-dihydroxydecenal. Biochim. Biophys. Acta, 792: 172-181 (1984).
-
(1984)
Biochim. Biophys. Acta
, vol.792
, pp. 172-181
-
-
Benedetti, A.1
Comporti, M.2
Fulceri, R.3
Esterbauer, H.4
-
4
-
-
0019173874
-
Identîcation and determination of 11-oxo-D8-tetrahydrocannabinol as an intermediate metabolite of D8-tetrahydrocannabinol in the mouse brain and liver
-
Watanabe, K., Yamamoto, I., Oguri, K. and Yoshimura, H.: Identîcation and determination of 11-oxo-D8-tetrahydrocannabinol as an intermediate metabolite of D8-tetrahydrocannabinol in the mouse brain and liver. J. Pharmacobio-Dyn., 3: 686-691 (1980).
-
(1980)
J. Pharmacobio-Dyn.
, vol.3
, pp. 686-691
-
-
Watanabe, K.1
Yamamoto, I.2
Oguri, K.3
Yoshimura, H.4
-
5
-
-
0018856770
-
Comparison in mice of pharmacological eŝects of D8-tetrahydrocannabinol and its metabolites oxidized at 11-position
-
Watanabe, K., Yamamoto, I., Oguri, K. and Yoshimura, H.: Comparison in mice of pharmacological eŝects of D8-tetrahydrocannabinol and its metabolites oxidized at 11-position. Eur. J. Pharmacol., 63: 1-6 (1980).
-
(1980)
Eur. J. Pharmacol.
, vol.63
, pp. 1-6
-
-
Watanabe, K.1
Yamamoto, I.2
Oguri, K.3
Yoshimura, H.4
-
6
-
-
0023927661
-
Oxygenation mechanism in the oxidation of xenobiotic aldehyde to carboxylic acid by hepatic microsomes
-
Yamamoto, I., Watanabe, K., Narimatsu, S. and Yoshimura, H.: Oxygenation mechanism in the oxidation of xenobiotic aldehyde to carboxylic acid by hepatic microsomes. Biochem. Biophys. Res. Commun., 153: 779-782 (1988).
-
(1988)
Biochem. Biophys. Res. Commun.
, vol.153
, pp. 779-782
-
-
Yamamoto, I.1
Watanabe, K.2
Narimatsu, S.3
Yoshimura, H.4
-
7
-
-
0025139064
-
Hepatic microsomal oxygenation of aldehydes to carboxylic acids
-
Watanabe, K., Narimatsu, S., Yamamoto, I. and Yoshimura, H.: Hepatic microsomal oxygenation of aldehydes to carboxylic acids. Biochem. Biophys. Res. Commun., 166: 1308-1312 (1990).
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.166
, pp. 1308-1312
-
-
Watanabe, K.1
Narimatsu, S.2
Yamamoto, I.3
Yoshimura, H.4
-
8
-
-
0025907945
-
Oxygenation mechanism in conversion of aldehyde to carboxylic acid catalyzed by a cytochrome P450 isozyme.
-
Watanabe, K., Narimatsu, S., Yamamoto, I. and Yoshimura, H.: Oxygenation mechanism in conversion of aldehyde to carboxylic acid catalyzed by a cytochrome P450 isozyme. J. Biol. Chem., 266: 2709-2711 (1991).
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 2709-2711
-
-
Watanabe, K.1
Narimatsu, S.2
Yamamoto, I.3
Yoshimura, H.4
-
9
-
-
0025912205
-
Catalytic activity of cytochrome P450 isozymes purîed from rat liver in converting 11-oxo-D8- tetrahydrocannabinol to D8-tetrahydrocannabinol-11-oic acid.
-
Watanabe, K., Matsunaga, T., Narimatsu, S., Yamamoto, I., Imaoka, S., Funae, Y. and Yoshimura, H.: Catalytic activity of cytochrome P450 isozymes purîed from rat liver in converting 11-oxo-D8- tetrahydrocannabinol to D8-tetrahydrocannabinol-11-oic acid. Biochem. Pharmacol., 42: 1255-1259 (1991).
-
(1991)
Biochem. Pharmacol.
, vol.42
, pp. 1255-1259
-
-
Watanabe, K.1
Matsunaga, T.2
Narimatsu, S.3
Yamamoto, I.4
Imaoka, S.5
Funae, Y.6
Yoshimura, H.7
-
10
-
-
0027494278
-
Cytochrome P450 isozymes catalyzing the hepatic microsomal oxidation of 9-anthraldehyde to 9-anthracene carboxylic acid in adult male rats
-
Matsunaga, T., Iwawaki, Y., Watanabe, K., Narimatsu, S., Yamamoto, I., Imaoka, S., Funae, Y. and Yoshimura, H.: Cytochrome P450 isozymes catalyzing the hepatic microsomal oxidation of 9-anthraldehyde to 9-anthracene carboxylic acid in adult male rats. Biol. Pharm. Bull., 16: 866-869 (1993).
-
(1993)
Biol. Pharm. Bull.
, vol.16
, pp. 866-869
-
-
Matsunaga, T.1
Iwawaki, Y.2
Watanabe, K.3
Narimatsu, S.4
Yamamoto, I.5
Imaoka, S.6
Funae, Y.7
Yoshimura, H.8
-
11
-
-
0027296638
-
A cytochrome P450 isozyme having aldehyde oxygenase activity plays a major role in metabolizing cannabinoids by mouse hepatic microsomes
-
Watanabe, K., Narimatsu, S., Matsunaga, T., Yamamoto, I. and Yoshimura, H.: A cytochrome P450 isozyme having aldehyde oxygenase activity plays a major role in metabolizing cannabinoids by mouse hepatic microsomes. Biochem. Pharmacol., 46: 405-411 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 405-411
-
-
Watanabe, K.1
Narimatsu, S.2
Matsunaga, T.3
Yamamoto, I.4
Yoshimura, H.5
-
12
-
-
0025643186
-
Cytochrome P-450 isozymes in metabolic activation of D9-tetrahydrocannabinol by rat liver microsomes
-
Narimatsu, S., Watanabe, K., Matsunaga, T., Yamamoto, I., Imaoka, S., Funae, Y. and Yoshimura, H.: Cytochrome P-450 isozymes in metabolic activation of D9-tetrahydrocannabinol by rat liver microsomes. Drug Metab. Dispos., 18: 943-948 (1990).
-
(1990)
Drug Metab. Dispos.
, vol.18
, pp. 943-948
-
-
Narimatsu, S.1
Watanabe, K.2
Matsunaga, T.3
Yamamoto, I.4
Imaoka, S.5
Funae, Y.6
Yoshimura, H.7
-
13
-
-
0026006856
-
Acetaldehyde as a substrate for ethanol-inducible cytochrome P450 (CYP2E1)
-
Terelius, Y., Norsten-Hoog, C., Cronholm, T. and Ingelman-Sundberg, M.: Acetaldehyde as a substrate for ethanol-inducible cytochrome P450 (CYP2E1). Biochem. Biophys. Res. Commun., 179: 689-694 (1991).
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.179
, pp. 689-694
-
-
Terelius, Y.1
Norsten-Hoog, C.2
Cronholm, T.3
Ingelman-Sundberg, M.4
-
14
-
-
0026559141
-
Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid
-
Roberts, E. S., Vaz, A. D. N. and Coon, M. J.: Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid, retinol and retinal. Mol. Pharmacol., 41: 427-433 (1992).
-
(1992)
retinol and retinal. Mol. Pharmacol.
, vol.41
, pp. 427-433
-
-
Roberts, E.S.1
Vaz, A.D.N.2
Coon, M.J.3
-
15
-
-
0016138983
-
The oxidation of D1- and D6-tetrahydrocannabinol with selenium dioxide
-
Inayama, S., Sawa, A. and Hosoya, E.: The oxidation of D1- and D6-tetrahydrocannabinol with selenium dioxide. Chem. Pharm. Bull., 22: 1519-1525 (1974).
-
(1974)
Chem. Pharm. Bull.
, vol.22
, pp. 1519-1525
-
-
Inayama, S.1
Sawa, A.2
Hosoya, E.3
-
16
-
-
0015864009
-
A urinary metabolite: isolation and synthesis
-
D6- Tetrahydrocannabinol-7-oic acid
-
Mechoulam, R., Ben-Zvi, Z., Agurell, S., Nilsson, I. M., Nilsson, J. L. G., Edery, H. and Grunfeld, Y.: D6- Tetrahydrocannabinol-7-oic acid. A urinary metabolite: isolation and synthesis. Experientia, 29: 1193-1195 (1973).
-
(1973)
Experientia
, vol.29
, pp. 1193-1195
-
-
Mechoulam, R.1
Ben-Zvi, Z.2
Agurell, S.3
Nilsson, I.M.4
Nilsson, J.L.G.5
Edery, H.6
Grunfeld, Y.7
-
17
-
-
0018764929
-
Synthesis and psychotropic activity of side chain hydroxylated D6-tetrahydrocannabinol metabolite
-
Ohlsson, A., Agurell, S., Leander, K., Dahmen, J., Edery, H., Porath, G., Levy, S. and Mechoulam, R.: Synthesis and psychotropic activity of side chain hydroxylated D6-tetrahydrocannabinol metabolite. Acta Pharm. Suec., 16: 21-33 (1979).
-
(1979)
Acta Pharm. Suec.
, vol.16
, pp. 21-33
-
-
Ohlsson, A.1
Agurell, S.2
Leander, K.3
Dahmen, J.4
Edery, H.5
Porath, G.6
Levy, S.7
Mechoulam, R.8
-
18
-
-
0029114516
-
Involvement of CYP2C in the metabolism of cannabinoids by human hepatic microsomes from an old woman.
-
Watanabe, K., Matsunaga, T., Yamamoto, I., Funae, Y. and Yoshimura, H.: Involvement of CYP2C in the metabolism of cannabinoids by human hepatic microsomes from an old woman. Biol Pharm. Bull., 18: 1138-1141 (1995).
-
(1995)
Biol Pharm. Bull.
, vol.18
, pp. 1138-1141
-
-
Watanabe, K.1
Matsunaga, T.2
Yamamoto, I.3
Funae, Y.4
Yoshimura, H.5
-
19
-
-
0025951783
-
Fluorometric assay of microsomal aldehyde oxygenase activity: 9-anthraldehyde as a substrate.
-
Watanabe, K., Ozaki, M., Matsunaga, T., Yamamoto, I. and Yoshimura, H.: Fluorometric assay of microsomal aldehyde oxygenase activity: 9-anthraldehyde as a substrate. Anal. Biochem., 198: 134-137 (1991).
-
(1991)
Anal. Biochem.
, vol.198
, pp. 134-137
-
-
Watanabe, K.1
Ozaki, M.2
Matsunaga, T.3
Yamamoto, I.4
Yoshimura, H.5
-
20
-
-
0033786798
-
CYP3A4 is a major isoform responsible for oxidation of 7-hydroxy-D8-tetrahydrocannabinol to 7-oxo-D8-tetrahydrocannabinol in human liver microsomes.
-
Matsunaga, T., Kishi, N., Higuchi, S., Watanabe, K., Ohshima, T. and Yamamoto, I.: CYP3A4 is a major isoform responsible for oxidation of 7-hydroxy-D8-tetrahydrocannabinol to 7-oxo-D8-tetrahydrocannabinol in human liver microsomes. Drug Metab. Dispos., 28: 1291-1296 (2000).
-
(2000)
Drug Metab. Dispos.
, vol.28
, pp. 1291-1296
-
-
Matsunaga, T.1
Kishi, N.2
Higuchi, S.3
Watanabe, K.4
Ohshima, T.5
Yamamoto, I.6
-
21
-
-
0025078907
-
Inhibition of hepatic microsomal cytochrome P450 by cannabidiol in adult male rats.
-
Narimatsu, S., Watanabe, K., Matsunaga, T., Yamamoto, I., Imaoka, S., Funae, Y. and Yoshimura, H.: Inhibition of hepatic microsomal cytochrome P450 by cannabidiol in adult male rats. Chem. Pharm. Bull., 38: 1365-1368 (1990).
-
(1990)
Chem. Pharm. Bull.
, vol.38
, pp. 1365-1368
-
-
Narimatsu, S.1
Watanabe, K.2
Matsunaga, T.3
Yamamoto, I.4
Imaoka, S.5
Funae, Y.6
Yoshimura, H.7
-
22
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J.: Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193: 265-275 (1951).
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
23
-
-
0028858960
-
Cytochrome P450 inhibitors: evaluation of specîcities in the in vitro metabolism of therapeutic agents by human liver microsomes
-
Newton, D. J., Wang, R. W. and Lu, A. Y. H.: Cytochrome P450 inhibitors: evaluation of specîcities in the in vitro metabolism of therapeutic agents by human liver microsomes. Drug Metab. Dispos., 23: 154-158 (1995).
-
(1995)
Drug Metab. Dispos
, vol.23
, pp. 154-158
-
-
Newton, D.J.1
Wang, R.W.2
Lu, A.Y.H.3
-
24
-
-
0028970047
-
Ketoconazole and sulfaphenazole as the respective selective inhibitors of P4503A and 2C9
-
Baldwin, S. J., Bloomer, J. C., Smith, G. J., Ayrton, A. D., Clarke, S. E. and Chenery, R. J.: Ketoconazole and sulfaphenazole as the respective selective inhibitors of P4503A and 2C9. Xenobiotica, 25: 261-270 (1995).
-
(1995)
Xenobiotica
, vol.25
, pp. 261-270
-
-
Baldwin, S.J.1
Bloomer, J.C.2
Smith, G.J.3
Ayrton, A.D.4
Clarke, S.E.5
Chenery, R.J.6
-
25
-
-
0030056594
-
Specîcity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes
-
Ono, S., Hatanaka, T., Hotta, H., Satoh, T., Gonzalez, F. J. and Tsutsui, M.: Specîcity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes. Xenobiotica, 26: 681-693 (1996).
-
(1996)
Xenobiotica
, vol.26
, pp. 681-693
-
-
Ono, S.1
Hatanaka, T.2
Hotta, H.3
Satoh, T.4
Gonzalez, F.J.5
Tsutsui, M.6
-
26
-
-
0024541342
-
Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principle enzyme involved in the bioactivation of aflatoxins in human liver
-
Shimada, T. and Guengerrich, F. P.: Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principle enzyme involved in the bioactivation of aflatoxins in human liver. Proc. Natl. Acad. Sci., 86: 462-465 (1989).
-
(1989)
Proc. Natl. Acad. Sci.
, vol.86
, pp. 462-465
-
-
Shimada, T.1
Guengerrich, F.P.2
-
27
-
-
0022921460
-
Pharmacokinetics and metabolism of D1-tetrahydrocannabinol and other cannabinoids with emphasis on man
-
Agurell, S., Halldin, M., Lindgren, J.-E., Ohlsson, A., Widman, M., Gillespie, H. and Hollister, L.: Pharmacokinetics and metabolism of D1-tetrahydrocannabinol and other cannabinoids with emphasis on man. Pharmacol. Rev., 38: 21-43 (1986).
-
(1986)
Pharmacol. Rev.
, vol.38
, pp. 21-43
-
-
Agurell, S.1
Halldin, M.2
Lindgren, J.-E.3
Ohlsson, A.4
Widman, M.5
Gillespie, H.6
Hollister, L.7
-
28
-
-
85024471923
-
Metabolism of tetrahydrocannabinol, cannabidiol and cannabinol, the major constituents of marihuana in man
-
Japanese
-
Yamamoto, I. and Narimatsu, S.: Metabolism of tetrahydrocannabinol, cannabidiol and cannabinol, the major constituents of marihuana in man. Japanese J. Forensic Toxicol., 9: 2-16 (1991).
-
(1991)
J. Forensic Toxicol.
, vol.9
, pp. 2-16
-
-
Yamamoto, I.1
Narimatsu, S.2
-
29
-
-
0026586613
-
Human hepatic metabolism of D1-tetrahydrocannabinol
-
Bornheim, L. M., Lasker, J. M. and Raucy, J. L.: Human hepatic metabolism of D1-tetrahydrocannabinol. Drug Metab. Dispos., 20: 241-246 (1992).
-
(1992)
Drug Metab. Dispos.
, vol.20
, pp. 241-246
-
-
Bornheim, L.M.1
Lasker, J.M.2
Raucy, J.L.3
-
30
-
-
0030007901
-
Microsomal aldehyde oxygenase (MALDO): purîcation characterization of cytochrome P450 isozyme responsible for oxidation of 9-anthraldehyde to 9- anthracene carboxylic acid in monkey liver
-
Matsunaga, T., Iwawaki, Y., Watanabe, K., Yamamoto, I., Kageyama, T. and Yoshimura, H.: Microsomal aldehyde oxygenase (MALDO): purîcation and characterization of cytochrome P450 isozyme responsible for oxidation of 9-anthraldehyde to 9- anthracene carboxylic acid in monkey liver. J. Biochem., 119: 617-625 (1996).
-
(1996)
J. Biochem.
, vol.119
, pp. 617-625
-
-
Matsunaga, T.1
Iwawaki, Y.2
Watanabe, K.3
Yamamoto, I.4
Kageyama, T.5
Yoshimura, H.6
|