Simultaneous determination of hydroxysafflor yellow A and ferulic acid in rat plasma after oral administration of the co-extractum of Rhizoma chuanxiong and Flos Carthami by HPLC-diode array detector

Biomedical Chromatography

Volumn 21, Issue 8, 2007, Pages 816-822

  Qi, Jianping ^a   Jin, Xuefeng ^a   Huang, Luosheng ^a   Ping, Qineng ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Ferulic acid; HPLC diode array detector; Hydroxysafflor yellow A; Pharmacokinetic

Indexed keywords

BODY FLUIDS; POTASSIUM COMPOUNDS; RATS;

CHUANXIONG; DIODE ARRAY DETECTORS; FERULIC ACIDS; HPLC METHOD; HPLC-DIODE ARRAY DETECTOR; HYDROXYSAFFLOR YELLOW A; ORAL ADMINISTRATION; RAT PLASMA; SIMPLE++; SIMULTANEOUS DETERMINATIONS;

PHARMACOKINETICS;

ACETONITRILE; FERULIC ACID; FLOS CATHARMI; HYDROXYSAFFLOR YELLOW A; PERCHLORIC ACID; PHOSPHORIC ACID; PLANT MEDICINAL PRODUCT; POTASSIUM DIHYDROGEN PHOSPHATE; RHIZOMA CHUANXIONG; RIBOFLAVIN; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; ASSAY; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG STRUCTURE; ELUTION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PH; RAT; SUPERNATANT;

FLOS; RATTUS;

EID: 34547673599     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.821     Document Type: Article

References (8)

1. Bourne LC and Evans CR. Bioavailability of ferulic acid. Biochemical and Biophysical Research Communications 1998; 253: 222-227.
2. Gao HS. Science of TCM Prescriptions. Hunan Science and Technology: Changsha 2003; 175.
3. Li YJ and Bi KS. HPLC determination of ferulic acid in rat plasma after oral administration of Rhizoma chuanxiong and its compound preparation. Biomedical Chromatography 2003; 17: 543-546.
4. The Pharmacopoeia of PRC, Part I. Chemical Industrial Publishing House: Beijing; 2005; 636.
5. Wang JM and Jiang MY. Pharmacology of Traditional Chinese Medicine. Shanghai Science and Technology: Shanghai, 1985; 73.
6. Wen AD, Huang X, Jiang YP and Fan YX. High-performance liquid chromatographic determination of free ferulic acid in serum of rabbits with blood stasis. Acta Pharmaceutica Sinica 1995, 30: 762-767.
7. Xiong QM, Min C, Liu Y, Pan MF and Liu QH. Pharmacokinetics of hydroxysafflor yellow A. Chinese Journal of Pharmaceuticals 2004; 35: 228-230.
8. Zhu HB, Wang ZH, Ma CJ, Tian JW, Fu FH, Li CL, Guo D, Roder E and Liu K. Neuroprotective effects of hydroxysafflor yellow A: in vitro and in vivo studies. Planta Medica 2003; 69: 429-433.