Maternal and umbilical venous adrenomedullin and nitric oxide levels in intrauterine growth restriction

Journal of Maternal-Fetal and Neonatal Medicine

Volumn 20, Issue 7, 2007, Pages 521-525

  Akturk, Aysima ^a   Onal, E Esra ^a,c   Atalay, Yildiz ^a   Yurekli, Muhittin ^b   Erbas, Deniz ^a   Okumus, Nurullah ^a   Turkyilmaz, Canan ^a   Unal, Suna ^a   Ergenekon, Ebru ^a   Koc, Esin ^a   Himmetoglu, Özdemir ^a  

^a GAZI UNIVERSITY FACULTY OF MEDICINE   (Turkey)

^b INONU UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^c NONE   (Turkey)

Author keywords

Adrenomedullin; Fetoplacental circulation; Intrauterine growth restriction; Nitric oxide; Vasodilator peptide

Indexed keywords

ADRENOMEDULLIN; NITRIC OXIDE;

ANALYTIC METHOD; ARTICLE; BLOOD FLOW; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FEMALE; GESTATIONAL AGE; HUMAN; INFANT; INTRAUTERINE GROWTH RETARDATION; MAJOR CLINICAL STUDY; MALE; MATERNAL BLOOD; NEWBORN; PRIORITY JOURNAL; SMALL FOR DATE INFANT; UMBILICAL CORD BLOOD;

ADRENOMEDULLIN; ADULT; DELIVERY, OBSTETRIC; FEMALE; FETAL BLOOD; FETAL GROWTH RETARDATION; HUMANS; INFANT, NEWBORN; INFANT, SMALL FOR GESTATIONAL AGE; MALE; NITRIC OXIDE; PLACENTAL CIRCULATION; PREGNANCY;

EID: 34547653941     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.1080/14767050701412263     Document Type: Article

References (30)

1. Blair E, Stanley F. Intrauterine growth and spastic cerebral palsy II. The association with morphology at birth. Early Hum Dev 1992;28:91-103.
2. De Wolf F, Robertson WB, Brosens I. Inadequate maternal vascular response to placentation in pregnancies complicated by preeclampsia and by small for gestational age infants. Br J Obstet Gynaecol 1986;93:1049-1059.
3. Kitamura K, Kangawa K, Kawamoto M, Ichiki Y, Nakamura S, Matsuo H, Eto T. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun 1993;192:553-556.
4. Ishizaka Y, Tanaka M, Kitamura K, Kitamura K, Kangawa K, Minamino N, Matsuo H, Eto T. Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells. Biochem Biophys Res Commun 1994;200:642-646.
5. Di Iorio R, Marinoni E, Letizia C, Cosmi EV. Adrenomedullin in perinatal medicine. Regul Pept 2003;112:103-113.
6. Di Iorio R, Marinoni E, Letizia C, Gazzolo D, Lucchini C, Cosmi EV. Adrenomedullin is increased in the fetoplacental circulation in intrauterine growth restriction with abnormal umbilical artery waveforms. Am J Obstet Gynecol 2000;182:650-654.
7. Apodaca CC, Moore KH, Rossignol TM, Pierce B, Matej LA, Hume RF Jr, Calhoun BC. Localization of messenger ribonucleic acid for adrenomedullin and adrenomedullin receptor in the human placenta in normal pregnancies and pregnancies complicated by oligohydramnios. Am J Obstet Gynecol 2000;183:1213-1219.
8. Knowles RG, Moncada S. Nitric oxide synthases in mammals. Biochem J 1994;298:249-258.
9. Myatt L, Brewer AS, Langdon G, Brockman DE. Attenuation of the vasoconstrictor effects of thromboxane and endothelin by nitric oxide in the human fetal-placental circulation. Am J Obstet Gynecol 1992;164:687-692.
10. Lyall F, Greer IA, Young A, Myatt L. Nitric oxide concentrations are increased in the feto-placental circulation in intrauterine growth restriction. Placenta 1996;17:165-168.
11. Wijnberger LD, Krediet TG, Egberts J, van Bel F. Nitric oxide production during the early neonatal period in small-for-gestational-age infants. Acta Paediatr 2001;90:569-572.
12. Casanello P, Sobrevia L. Intrauterine growth retardation is associated with reduced activity and expression of the cationic amino acid transport systems y+/hCAT-1 and y+/hCAT-2B and lower activity of nitric oxide synthase in human umbilical vein endothelial cells. Circ Res 2002;91:127-134.
13. Lubchenco LO, Hansman C, Boyd E. Intrauterine growth as estimated from live born birth-weight data at 24-42 weeks of gestation. Pediatrics 1963;32:793-798.
14. Mant CT, Hudges RS. High performance liquid chromatography of peptides and proteins. Boca Raton: CRC Press; 1991.
15. Miranda KM, Espey MG, Wink DA. A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide 2001;5:62-71.
16. Morris NH, Sooranna SR, Learmont JG, Poston L, Ramsey B, Pearson JD, Steer PJ. Nitric oxide synthase activities in placental tissue from normotensive, pre-eclamptic and growth retarded pregnancies. Br J Obstet Gynaecol 1995;102:711-714.
17. Hata T, Hashimoto M, Manabe A, Aoki S, Iida K, Masumura S, Miyazaki K. Maternal and fetal nitric oxide synthesis is decreased in pregnancies with small for gestational age infants. Hum Reprod 1998;13:1070-1073.
18. Witlin AG, Li ZY, Wimalawansa SJ, Grady JJ, Grafe MR, Yallampalli C. Placental and fetal growth and development in late rat gestation is dependent on adrenomedullin. Biol Reprod 2002;67:1025-1031.
19. Yamashiro C, Hayashi K, Yanagihara T, Hata T. Plasma adrenomedullin levels in pregnancies with appropriate for gestational age and small for gestational age infants. J Perinat Med 2001;29:513-518.
20. Dotsch J, Hogen N, Nyul Z, Hanze J, Knerr I, Kirschbaum M, Rascher W. Increase of endothelial nitric oxide synthase and endothelin-1 mRNA expression in human placenta during gestation. Eur J Obstet Gynecol Reprod Biol 2001;97:163-167.
21. Kitamura K, Kato J, Kawamoto M, Tanaka M, Chino N, Kangawa K, Eto T. The intermediate form of glycine-extended adrenomedullin is the major circulating molecular form in human plasma. Biochem Biophys Res Commun 1998;244:551-555.
22. Elsasser TH, Kahl S, Martinez A, Montuenga L, Pio R, Cuttitta F. Adrenomedullin binding protein in the plasma of multiple species: Characterization by radioligand blotting. Endocrinology 1999;140:4908-4911.
23. Lah JJ, Frishman WH. Adrenomedullin a vasoactive and natriuretic peptide with therapeutic potential. Heart Dis 2000;2:259-265.
24. Hinson JP, Kapas S, Smith DM. Adrenomedullin, a multifunctional regulatory peptide. Endocr Rev 2000;21:138-167.
25. Shimekake Y, Nagata K, Ohta S, Kambayashi Y, Teraoka H, Kitamura K, Eto T, Kangawa K, Matsuo H. Adrenomedullin stimulates two signal transduction pathways, cAMP accumulation and Ca21 mobilization, in bovine aortic endothelial cells. J Biol Chem 1995;270:4412-4417.
26. Marinoni E, Di Iorio R, Letizia C, Villaccio B, Scucchi L, Cosmi EV. Immunoreactive adrenomedullin in human fetoplacental tissues. Am J Obstet Gynecol 1998;179:784-787.
27. Boldt T, Luukkainen P, Fyhrquist F, Pohjavuori M, Andersson S. Birth stress increases adrenomedullin in the newborn. Acta Paediatr 1998;87:93-94.
28. Di Iorio R, Marinoni E, Letizia C, Alo P, Villaccio B, Poverini R, Cosmi EV. Influence of labor on fetoplacental adrenomedullin concentrations. Am J Obstet Gynecol 2001;185:697-702.
29. Endo A, Izumi H, Ayusawa M, Minato M, Takahashi S, Harada K. Spontaneous labor increases nitric oxide synthesis during the early neonatal period. Pediatr Int 2001;43:340-342.
30. Jo T, Takauchi Y, Nakajima Y, Fukami K, Kosaka H, Terada N. Maternal or umbilical venous levels of nitrite/nitrate during pregnancy and at delivery. In Vivo 1998;12:523-526.