The role of CXCR2 in systemic neovascularization of the mouse lung

Journal of Applied Physiology

Volumn 103, Issue 2, 2007, Pages 594-599

  Sánchez, Jesús ^a   Moldobaeva, Aigul ^a   McClintock, Jessica ^a   Jenkins, John ^a   Wagner, Elizabeth M ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

Angiogenesis; Chemokines; Macrophage inflammatory protein 2

Indexed keywords

CHEMOKINE RECEPTOR CXCR2; MACROPHAGE INFLAMMATORY PROTEIN 2; CHEMOKINE; CHEMOKINE RECEPTOR CXCR1; MIP 2 PROTEIN, MOUSE; MIP-2 PROTEIN, MOUSE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY LIGATION; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; IN VIVO STUDY; LUNG FUNCTION; LUNG HOMOGENATE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY ARTERY OCCLUSION; SYSTEMIC CIRCULATION; ANIMAL; BAGG ALBINO MOUSE; BLOOD FLOW; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; LIGATION; LUNG; MALE; MOUSE MUTANT; PHYSIOLOGY; VASCULARIZATION;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CHEMOKINES; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; LIGATION; LUNG; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOVASCULARIZATION, PHYSIOLOGIC; PULMONARY ARTERY; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B; REGIONAL BLOOD FLOW;

EID: 34547645193     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00037.2007     Document Type: Article

References (30)

1. 2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity. J Immunol 165: 5269-5277, 2000.
2. Arenberg DA, Keane MP, DiGiovine B, Kunkel SL, Morris SB, Xue YY, Burdick MD, Glass MC, Iannettoni MD, Strieter RM. Epithelial-neutrophil activating peptide (ENA-78) is an important angiogenic factor in non-small cell lung cancer. J Clin Invest 102: 465-472, 1998.
3. 2 ligands in vascular remodeling during bronchiolitis obliterans syndrome. J Clin Invest 115: 1150-1162, 2005.
4. Brinson GM, Noone PG, Mauro MA, Knowles MR, Yankaskas JR, Sandhu JS, Jaques PF. Bronchial artery embolization for the treatment of hemoptysis in patients with cystic fibrosis. Am J Respir Crit Care Med 157: 1951-1958, 1998.
5. Charan NB, Carvalho P. Angiogenesis in bronchial circulatory system after unilateral pulmonary artery obstruction. J Appl Physiol 82: 284-291, 1997.
6. Fadel E, Mazmanian GM, Chapelier A, Baudet B, Detruit H, de Montpreville V, Libert JM, Wartski M, Herve P, Dartevelle P. Lung reperfusion injury after chronic or acute unilateral pulmonary artery occlusion. Am J Respir Crit Care Med 157: 1294-1300, 1998.
7. 1 is a functional receptor for GCP-2/CXCL6 and IL-8/CXCL8. J Biol Chem 282: 11658-11666, 2007.
8. 1. Cytokine 31: 9-17, 2005.
9. Karsner H, Ghoreyeb A. Studies in infarction: the circulation in experimental pulmonary embolism. J Exp Med 18: 507-522, 1913.
10. Keane MP, Belperio JA, Moore TA, Moore BB, Arenberg DA, Smith RE, Burdick MD, Kunkel SL, Strieter RM. Neutralization of the CXC chemokine, macrophage inflammatory protein-2, attenuates bleomycin-induced pulmonary fibrosis. J Immunol 162: 5511-5518, 1999.
11. 2 inhibits tumor growth and angiogenesis in a murine model of lung cancer. J Immunol 172: 2853-2860, 2004.
12. Li A, Dubey S, Varney ML, Dave BJ, Singh RK. IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis. J Immunol 170: 3369-3376, 2003.
13. Li X, Wilson JW. Increased vascularity of the bronchial mucosa in mild asthma. Am J Respir Crit Care Med 156: 229-233, 1997.
14. McClintock JY, Wagner EM. Role of IL-6 in systemic angiogenesis of the lung. J Appl Physiol 99: 861-866, 2005.
15. Mitzner W, Lee W, Georgakopoulos D, Wagner E. Angiogenesis in the mouse lung. Am J Pathol 157: 93-101, 2000.
16. 1 is expressed in the mouse. Mol Immunol 43: 897-914, 2006.
17. 2. Am J Physiol Lung Cell Mol Physiol 288: L1117-L1123, 2005.
18. Murphy PM, Baggiolini M, Charo IF, Hebert CA, Horuk R, Matsushima K, Miller LH, Oppenheim JJ, Power CA. International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev 52: 145-176, 2000.
19. Remy-Jardin M, Duhamel A, Deken V, Bouaziz N, Dumont P, Remy J. Systemic collateral supply in patients with chronic thromboembolic and primary pulmonary hypertension: assessment with multi-detector row helical CT Angiography. Radiology 235: 274-281, 2005.
20. Salcedo R, Resau JH, Halverson D, Hudson EA, Dambach M, Powell D, Wasserman K, Oppenheim JJ. Differential expression and responsiveness of chemokine receptors (CXCR1-3) by human microvascular endothelial cells and umbilical vein endothelial cells. FASEB J 14: 2055-2064, 2000.
21. 2 through Rho and Rac signaling pathways. Am J Physiol Lung Cell Mol Physiol 280: L1094-L1103, 2001.
22. Srisuma S, Biswal SS, Mitzner WA, Gallagher SJ, Mai KH, Wagner EM. Identification of genes promoting angiogenesis in mouse lung by transcriptional profiling. Am J Respir Cell Mol Biol 29: 172-179, 2003.
23. Strieter R, Kunkel SL. Chemokines. In: The Lung, edited by Crystal RG, West JB, Barnes PJ, and Weibel ER. Philadelphia: Lippincott-Raven, 1997, p. 155-186.
24. Strieter RM. Interleukin-8: a very important chemokine of the human airway epithelium. Am J Physiol Lung Cell Mol Physiol 283: L688-L689, 2002.
25. Strieter RM, Belperio JA, Keane MP. CXC chemokines in vascular remodeling related to pulmonary fibrosis. Am J Respir Cell Mol Biol 29: S67-69, 2003.
26. Strieter RM, Polverini PJ, Kunkel SL, Arenberg DA, Burdick MD, Kasper J, Dzuiba J, Van Damme J, Walz A, Marriott D, Chan S-Y, Roczniak S, Shanafelt AB. The functional role of the ELR motif in CXC chemokine-mediated angiogenesis. J Biol Chem 270: 27348-27357, 1995.
27. Wagner EM, Karagulova G, Jenkins J, Bishai J, McClintock J. Changes in lung permeability after chronic pulmonary artery obstruction. J Appl Physiol 100: 1224-1229, 2006.
28. Wagner EM, Petrache I, Schofield B, Mitzner W. Pulmonary ischemia induces lung remodeling and angiogenesis. J Appl Physiol 100: 587-593, 2006.
29. Weibel ER. Early stages in the development of collateral circulation to the lung in the rat. Circ Res 8: 353-376, 1960.
30. Wislez M, Fujimoto N, Izzo JG, Hanna AE, Cody DD, Langley RR, Tang H, Burdick MD, Sato M, Minna JD, Mao L, Wistuba I, Strieter RM, Kurie JM. High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras. Cancer Res 66: 4198-4207, 2006.