Duplex Doppler ultrasonography in portal hypertension

Journal of Medical Ultrasound

Volumn 15, Issue 2, 2007, Pages 103-111

  Yang, Sien Sing ^a  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

Cirrhosis; Duplex Doppler; Portal hypertension; Vein flow velocity

Indexed keywords

GLYCERYL TRINITRATE; INTERFERON; METFORMIN; NADOLOL; PROPRANOLOL; SHU 508; SOMATOSTATIN; TERLIPRESSIN; VARDENAFIL;

ARTERY RESISTANCE; COLOR ULTRASOUND FLOWMETRY; COLORECTAL CARCINOMA; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DOPPLER ECHOGRAPHY; ESOPHAGUS VARICES; FLOW KINETICS; HEMODYNAMIC MONITORING; HEMODYNAMIC PARAMETERS; HEPATITIS C; HUMAN; LIVER BLOOD FLOW; LIVER CIRRHOSIS; LIVER DISEASE; LIVER METASTASIS; LIVER PERFUSION; NONALCOHOLIC FATTY LIVER; PATHOGENESIS; PATIENT SAFETY; PORTAL HYPERTENSION; PORTAL VEIN; PULSATILE FLOW; REVIEW;

EID: 34547596783     PISSN: 09296441     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0929-6441(08)60028-4     Document Type: Review

References (110)

1. Laleman W, Van Landeghem L, Wilmer A, et al. Portal hypertension: from pathophysiology to clinical practice. Liver Int 2005;5:1079-90.
2. Rodriguez-Vilarrupla A, Fernandez M, Bosch J, et al. Current concepts on the pathophysiology of portal hypertension. Ann Hepatol 2007;6:8-36.
3. Groszmann RJ, Abraldes JG. Portal hypertension: from bedside to belch. J Clin Gastroenterol 2005;39 (Suppl 2):S125-30.
4. Groszmann R, Vorobioff JD, Gao H. Measurement of portal pressure: when, how and why to do it. Clin Liver Dis 2006; 10:499-512.
5. Bosch J, Garcia-Pagan JC, Berzigotti A, et al. Measurement of portal pressure and its role in the management of chronic liver disease. Semin Liver Dis 2006;26: 348-362.
6. Takahashi H, Suzuki M, Ikeda H, et al. Evaluation of quantitative portal venous, hepatic arterial and total hepatic tissue blood flow using xenon CT in alcoholic liver cirrhosis: comparison with liver cirrhosis C. Alcoholism 2007;31 (SUppl 1):S43-8.
7. Cohen El, Wilck EJ, Shapiro RS. Hepatic imaging in the 21 st century. Semin Liver Dis 2006;26:363-72.
8. Shiomi S, Iwata Y, Sasaki N, et al. Assessment of hepatic blood flow by PET with 150 water: Correlation between per-rectal portal scintigraphy with 99Tcm-pertechnetate and scintigraphy with 99Tcm-GSA. Nucl Med Commun 2000;21:533-8.
9. Shapiro RS, Stancato-Pasik A, Glajchen N, et al. Color Doppler applications in hepatic imaging. Clin Imaging 1998;22:272-9.
10. Moriyasu F. Doppler ultrasound in diagnosis of liver tumor and portal hypertension. Radiol Med 1993; 85(Suppl 1):44-55.
11. Coley BD. Pediatric applications of abdominal vascular Doppler imaging: Part I and II. Pediatric Radiol 2004; 34:757-71, 772-86.
12. Bolondi L, Gaiani S, Gebel M. Portohepatic vascular pathology and liver disease: diagnosis and monitoring. Eur J Ultrasound 1998;7(Suppl 3):S41-52.
13. Gupta D, Chawla YK, Dhiman RK, et al. Clinical significance of patent paraumbilical vein in patients with liver cirrhosis. Dig Dis Sci 2000;45:1861-4.
14. Bookstein JJ, Cho KJ, Davis GB, et al. Arterioportal communications: observations and hypotheses concerning transsinusoidal and transvasal types. Radiology 1982;142:581-90.
15. Colombato LA, Spahr L, Martinet JP, et al. Haemodynamic adaptation 2 months after transjugular intrahepatic portosystemic shunt (TIPS) in cirrhotic patients. Gut 1996;39:600-4.
16. Itkin M, Trerotola SO, Stavropoulos SW, et al. Portal flow and arterioportal shunting after transjugular intrahepatic portosystemic shunt creation. J Vasc Interv Radiol 2006;17:55-62.
17. Abraldes JG, Gilabert R, Turnes J, et al. Utility of color Doppler ultrasonography predicting TIPS dysfunction. Am J Gastroenterol 2005;100:2696-701.
18. Middleton WD, Teefey SA, Darcy MD. Doppler evaluation of transjugular intrahepatic portosystemic shunts. Ultrasound Q 2003;19:56-70.
19. Sugimoto H, Kaneko T, Takeda S, et al. The use of quantitative Doppler ultrasonography to predict posthepatectomy complications on the basis of hepatic hemodynamic parameters. Surgery 2002;132:431-40.
20. Mortele KJ, Cantisani V, Troisi R, et al. Preoperative liver donor evaluation: imaging and pitfalls. Liver Transplant 2003;9:S6-14.
21. Lai YC, Yang SS, Wu CH. Portal vein thrombosis after splenectomy in a patient with liver cirrhosis and esophageal varices. J Med Ultrasound 1997;5:21-5.
22. Stamou MK, Toutouzas GK, Kekis BP, et al. Prospective study of the incidence and risk factors of postsplenectomy thrombosis of the portal, mesenteric and splenic veins. Arch Surgery 2006;141:663-9.
23. Rossi S, Rosa L, Ravetta V, et al. Contrast-enhanced versus conventional and color Doppler sonography for the detection of thrombosis of the portal and hepatic venous systems. AJR Am J Roentgenol 2006;186:763-73.
24. Cheng YF, Chen CL, Huang TL, et al. Risk factors for intraoperative portal vein thrombosis in pediatric living donor liver transplantation. Clin Transplant 2004; 18:390-4.
25. Hirai T, Ohishi H, Yamada R, et al. Color Doppler sonographic assessment of intrahepatic hemodynamics and shunt patency after transjugular intrahepatic portosystemic shunt. Nippon Acta Radiol 1996; 56:470-6.
26. Wachsberg RH. Doppler ultrasound evaluation of transjugular intrahepatic portosystemic shunt function: pitfalls and artifacts. Ultrasound Q 2003;19:139-48.
27. Colombato LA, Spahr L, Martinet JP, et al. Haemodynamic adaptation two months after transjugular intrahepatic portosystemic shunt in cirrhotic patients. Gut 1996;39:600-4.
28. Abraldes GJ, Gilabert R, Turnes J, et al. Utility of color Doppler ultrasonography predicting TIPS dysfunction. Am J Gastroenterol 2005;100:2696-701.
29. Nakanishi S, Shiraki K, Yamamoto K, et al. Early graft hemodynamics in living related liver transplantation evaluated by Doppler ultrasonography. Int J Mol Med 2004;14:265-9.
30. Platt JF, Yutzy GG, Bude RO, et al. Use of Doppler sonography for revealing hepatic artery stenosis in liver transplant recipients. AJR Am J Roentgenol 1997; 168:473-6.
31. Garcia-Criado A, Gilabert R, Nicolau C, et al. Early detection of hepatic artery thrombosis after liver transplantation by Doppler ultrasonography: prognostic implications. J Ultrasound Med 2001;20:51-8.
32. Vit A, de Candia A, Como G, et al. Doppler evaluation of arterial complications of adult orthotopic liver transplantation. J Clin Ultrasound 2003;31:339-45.
33. Sabba C, Weltin GG, Cicchetti DV, et al. Observer variability in echo-Doppler measurements of portal flow in cirrhotic patients and normal volunteers. Gastroenterology 1990;98:1603-11.
34. Tai DI, Chuah SK, Chen CL, et al. Inter-observer variability of portal hemodynamics measured by Doppler ultrasound on three different locations of portal vein. J Clin Ultrasound 1996;24:61-6.
35. Hubner GH, Steudel N, Reissmann A, et al. Hepatic arterial Doppler sonography in patients with cirrhosis and controls: observer and equipment variability with use of the ultrasonic contrast agent SHU 508A. Z Gastroenterol 2005;43:639-45.
36. Hu JT, Yang SS, Lai YC, et al. Percentage of peak-to-peak pulsatility of portal blood flow can predict right-sided congestive heart failure. World J Gastroenterol 2003;9:1828-31.
37. Barakat M. Portal vein pulsatility and spectral width changes in patients with portal hypertension: relation to the severity of liver disease. Br J Radiol 2002;75: 417-21.
38. Rector WGJ, Hoefs JC, Hossack KF, et al. Hepatofugal portal flow in cirrhosis: observations on hepatic hemodynamics and the nature of the arterioportal communications. Hepatology 1988;8:16-20.
39. Rengo C, Brevetti G, Sorrentino G, et al. Portal vein pulsatility ratio provides a measure of right heart function in chronic heart failure. Ultrasound Med Biol 1998; 24:327-32.
40. Moriyasu F, Nishida O, Ban N, et al. Measurement of portal vascular resistance in patients with portal hypertension. Gastroenterology 1986;90:710-7.
41. Rehrer NJ, Smets A, Reynaert H, et al. Effect of exercise on portal vein blood flow in man. Med Sci Sports Exerc 2001;33:1533-7.
42. Nakai A, Sekiya I, Oya A, et al. Assessment of the hepatic arterial and portal venous blood flows during pregnancy with Doppler ultrasonography. Arch Gynecol Obstet 2002;266:25-9.
43. Yang SS, Wu CH, Chen TK, et al. Portal blood flow in acute hepatitis with and without ascites: a non-invasive measurement using ultrasonic Doppler. J Gastroenterol Hepatol 1995;10:36-41.
44. Chiu CH, Chang-Chien CS, Liaw YF, et al. Albumin gradient and portal vein velocity in severe viral hepatitis patients complicated with ascites. Hepatogastroenterology 2000;47:1700-2.
45. Chawla Y, Sreedharan A, Dhiman RK, et al. Portal hemodynamics in fulminant hepatic failure as assessed by duplex Doppler ultrasonography. Dig Dis Sci 2001; 46:504-8.
46. Perisic M, Ilic-Mostic T, Stojkovic M, et al. Doppler hemodynamic study in portal hypertension and hepatic encephalopathy. Hepatogastroenterology 2005;52: 156-60.
47. Watanabe A. Portal-systemic encephalopathy in non-cirrhotic patients: classification of clinical types, diagnosis and treatment. J Gastroenterol Hepatol 2000;15: 969-79.
48. Benoit JN, Granger DN. Splanchnic hemodynamics in chronic portal hypertension. Semin Liver Dis 1986;6: 287-98.
49. Kozaiwa K, Tajiri H, Yoshimura N, et al. Utility of duplex Doppler ultrasound in evaluating portal hypertension in children. J Pediatr Gastroenterol Nutr 1995; 21:215-9.
50. Kok TE, van der Jagt J, Haagsma EB, et al. The value of Doppler ultrasound in cirrhosis and portal hypertension. Scand J Gastroenterol 1999;34(Suppl 230):82-8.
51. Nakanishi S, Shiraki K, Yamamoto K, et al. Hemodynamics in the portal vein evaluated by pulse wave Doppler ultrasonography in patients with chronic hepatitis C treated with interferon. World J Gastroenterol 2005;11:396-9.
52. Taourel P, Blanc P, Dauzat M, et al. Doppler study of mesenteric, hepatic and portal circulation in alcoholic cirrhosis: relationship between quantitative Doppler measurements and the severity of portal hypertension and hepatic failure. Hepatology 1998;28:932-6.
53. Chiu KC, Sheu BS, Chuang CH. Portal venous flow pattern as a useful tool for predicting esophageal varix bleeding in cirrhotic patients. Dig Dis Sci 2005;50: 1170-4.
54. Sugimoto H, Kaneko T, Takeda S, et al. The use of quantitative Doppler ultrasonography to predict posthepatectomy complications on the basis of hepatic hemodynamic parameters. Surgery 2002;132:431-40.
55. Kalambokis G, Economou M, Paraskevi K, et al. Effects of somatostatin, terlipressin and somatostatin plus terlipressin on portal and systemic hemodynamics and renal sodium excretion in patients with cirrhosis. J Gastroenterol Hepatol 2005;20:1075-81.
56. Yang SS, Ralls PW, Korula J. The effect of oral nitro-glycerin on portal vein flow. J Clin Gastroenterol 1991; 13:173-7.
57. Deibert P, Schumacher YO, Ruecker G, et al. Effect of vardenafil, an inhibitor of phosphodiesterase-5, on portal haemodynamics in normal and cirrhotic liver - results of a pilot study. Aliment Pharmacol Ther 2006; 23:121-8.
58. Ludwig D, Schadel S, Bruning A, et al. 48-hour hemodynamic effects of octreotide on postprandial splanchnic hyperemia in patients with liver cirrhosis and portal hypertension: double-blind, placebo-controlled study. Dig Dis Sci 2000;45:1019-27.
59. Castano G, Viudez P, Carlevaro O, et al. Portal and systemic hemodynamic changes after propranolol and 5-isosorbide mononitrate combination therapy in cirrhotic patients [abstract]. J Hepatol 1999; 30(Suppl 1):194.
60. Berzigotti A, Rinaldi MF, Magalotti D, et al. Primary prophylaxis with nadolol in cirrhotic patients: Doppler patterns of splanchnic hemodynamics in good and poor responders. J Hepatol 2006;44:310-6.
61. Sagarad SV, Chawla YK, Dhiman RK. Portal hemodynamics after large-volume paracentesis in patients with liver cirrhosis and tense ascites. Dig Dis Sci 1998; 43:2470-2.
62. Moriyasu F, Nishida O, Ban N, et al. Congestion index of the portal vein. AJR Am J Roentgenol 1986;146:735-9.
63. Merkel C, Sacerdoti D, Bolognesi M, et al. Doppler sonography and hepatic vein catheterization in portal hypertension: assesment of agreement in evaluating severity and response to treatment. J Hepatol 1998; 28:622-30.
64. Moriyasu F, Nishida O, Ban N, et al. Measurement of portal vascular resistance in patients with portal hypertension. Gastroenterelogy 1986;90:710-7.
65. Sinha R. Grayscale and pulsed Doppler characteristics of non-cirrhotic portal fibrosis: a preliminary report. Clin Radiol 1999;54:156-9.
66. Kayacetin E, Efe D, Dogan C. Portal and splenic hemodynamics in cirrhotic patients: relationship between esophageal variceal bleeding and the severity of hepatic failure. J Gastroenterol 2004; 39:661-7.
67. Haag K, Rossle M, Ochs A, et al. Correlation of duplex sonography findings and portal pressure in 375 patients with portal hypertension. AJR Am J Roentgenol 1999;172:631-5.
68. Plestina S, Pulanic R, Kralik M, et al. Color Doppler ultrasonography is reliable in assessing the risk of esophageal variceal bleeding in patients with liver cirrhosis. Wien Klin Wochenschr 2005;117:711-7.
69. Li FH, Hao J, Xia JG, et al. Hemodynamic analysis of esophageal varices in patients with liver cirrhosis using color Doppler ultrasound. World J Gastroenterol 2005; 11:4560-5.
70. Miyajima H, Nomura M, Muguruma N, et al. Relationship among gastric motility, autonomic activity and portal hemodynamics in patients with liver cirrhosis. J Gastroenterol Hepatol 2001;16:647-59.
71. Ludwig D, Schwarting K, Korbel C, et al. The postprandial portal flow is related to the severity of portal hypertension and liver cirrhosis. J Hepatol 1998;28:631-8.
72. Platt JF, Rubin JM, Ellis JH. Hepatic artery resistance changes in portal vein thrombosis. Radiology 1995; 196:95-8.
73. Schneider AW, Kalk JF, Klein CP. Hepatic arterial pulsatility index in cirrhosis: correlation with portal pressure. J Hepatol 1999;30:876-81.
74. Colli A, Cocciolo M, Mumoli N, et al. Hepatic artery resistance in alcoholic liver disease. Hepatology 1998; 28:1182-6.
75. Bolognesi M, Sacerdoti D, Mescoli C, et al. Different hemodynamic patterns of alcoholic and viral end stage cirrhosis: analysis of explanted liver weight, degree of fibrosis and splanchnic Doppler parameters. Scand J Gastroenterol 2007;42:256-62.
76. Marder DM, DeMarino GB, Sumkin JH, et al. Liver transplant rejection: value of the resistive index in Doppler US of hepatic arteries. Radiology 1989;173: 127-9.
77. Asthana S, McClean PS, Stringer MD. Does the pediatric end-stage liver disease score or hepatic artery resistance index predict outcome after liver transplantation for biliary atresia? Pediatr Surg Int 2006;22: 697-700.
78. Mihmanli I, Kantarci F, Yilmaz MH, et al. Effect of diffuse fatty infiltration of the liver on hepatic artery resistance index. J Clin Ultrasound 2005;33:95-9.
79. Magalotti D, Marchesini G, Ramilli S, et al. Splanchnic haemodynamics in non-alcoholic fatty liver disease: effect of a dietary/pharmacological treatment; a pilot study. Digest Liver Dis 2004;36:406-11.
80. Sugimoto H, Kaneko T, Inoue S, et al Simultaneous Doppler measurement of portal venous peak velocity, hepatic arterial peak velocity and splenic arterial pulsatility index for assessment of hepatic circulation. Hepatogastroenterology 2002;49:793-7.
81. Capponi A, Rizzo G, Arduini D, et al. Splenic artery velocity waveforms in small-for-gestational-age fetuses: relationship with PH and blood gases measured in umbilical blood at cordocentesis. Am J Obstet Gynecol 1997;176:300-7.
82. Oz U, Kovanci E, Jeffress A, et al. Splenic artery Doppler in the prediction of the small-for-gestational age infant. Ultrasound Obstet Gynecol 2002;20:346-50.
83. Wicklein S, Mühlberg W, Richter B, et al. Increased splanchnic arterial vascular resistance in very old patients. Z Gerontol Geriatr 2007;40:37-42.
84. Rivolta R, Maggi A, Cazzaniga M, et al. Reduction of renal cortical blood flow assessed by Doppler in cirrhotic patients with refractory ascites. Hepatology 1998; 28:1235-40.
85. Abdallah AF, Bakr AM, El-Haggar M, et al. Renal hemodynamic changes in children with liver cirrhosis. Pediatr Nephrol 1999;13:854-8.
86. Celebi H, Donder E, Celiker H. Renal blood flow detection with Doppler ultrasonography in patients with hepatic cirrhosis. Arch Intern Med 1997;157: 564-6.
87. Leen E, Angerson WJ, Wotherspoon H, et al. Comparison of the Doppler perfusion index and intraoperative ultrasonography in diagnosing colorectal liver metastases: evaluation with postoperative follow-up results. Ann Surg 1994;220:663-7.
88. Leen E, Goldberg JA, Angerson WJ, et al. Potential role of Doppler perfusion index in selection of patients with colorectal cancer for adjuvant chemotherapy. Lancet 2000;355:34-7.
89. Oktar SO, Yucel C, Demirogullari T, et al. Doppler sonographic evaluation of hemodynamic changes in colorectal liver metastases relative to liver size. J Ultrasound Med 2006;25:575-82.
90. Kopljar M, Brkljacic B, Doko M, et al. Nature of Doppler perfusion index changes in patients with colorectal cancer liver metastases. J Ultrasound Med 2004; 23:1295-300.
91. Roumen RM, Scheltinga MR, Slooter GD, et al. Doppler perfusion index fails to predict the presence of occult hepatic colorectal metastases. Eur J Surg Oncol 2005;31:521-7.
92. Kakkos SK, Yarmenitis SD, Tsamandas AC, et al. Fatty liver in obesity: relation to Doppler perfusion index measurement of the liver. Scand J Gastroenterol 2000;35:976-80.
93. Hirota M, Kaneko T, Sugimoto H, et al. Intrahepatic circulatory time analysis of an ultrasound contrast agent in liver cirrhosis. Liver Int 2005;25:337-42.
94. Sudhamshu KC, Matsutani S, Maruyama H, et al. Doppler study of hepatic vein in cirrhotic patients: correlation with liver dysfunction and hepatic hemodynamics. World J Gastroenterol 2006;12:5853-8.
95. von Herbay A, Frieling T, Haussinger D. Association between duplex Doppler sonographic flow pattern in right hepatic vein and various liver diseases. J Clin Ultrasound 2001;29:25-30.
96. Dietrich CF, Lee JH, Gottschalk R, et al. Hepatic and portal vein flow pattern in correlation with intrahepatic fat deposition and liver histology in patients with chronic hepatitis C. AJR Am J Roentgenol 1998;171:437-43.
97. Baik SK, Kim JW, Kim HS, et al. Recent variceal bleeding: Doppler US hepatic vein waveform in assessment of severity of portal hypertension and vasoactive drug response. Radiology 2006;240:574-80.
98. Haktanir A, Cihan BS, Celenk C, et al. Value of Doppler sonography in assessing the progression of chronic viral hepatitis and in the diagnosis and grading of cirrhosis. J Ultrasound Med 2005;24:311-21.
99. Murat A, Akarsu S, Cihangiroglu M, et al. Assessment of Doppler waveform patterns and flow velocities of hepatic veins in children with acute viral hepatitis. Diagn Interv Radiol 2006;12:85-9.
100. Oguzkurt L, Yildirim T, Torun D, et al. Hepatic vein Doppler waveform in patients with diffuse fatty infiltration of the liver. Eur J Radiol 2005;54:253-7.
101. Carricart M, Denault AY, Couture P, et al. Incidence and significance of abnormal hepatic venous Doppler flow velocities before cardiac surgery. J Cardiothorac Vasc Anesth 2005;19:751-8.
102. Pedersen JF, Dakhil AZ, Jensen DB, et al. Abnormal hepatic vein Doppler waveform in patients without liver disease. Br J Radiol 2005;78:242-4.
103. Lim AK, Patel N, Eckersley RJ, et al. Can Doppler sonography grade he severity of hepatitis C-related liver disease? AJR Am J Roentgenol 2005;184: 1848-53.
104. Albrecht T, Blomley MJ, Cosgrove DO, et al. Non-invasive diagnosis of hepatic cirrhosis by transit-time analysis of an ultrasound contrast agent. Lancet 1999;353:1579-83.
105. Blomley MJ, Lim AK, Harvey CJ, et al. Liver microbubble transit time compared with histology and Child-Pugh score in diffuse liver disease: a cross sectional study. Gut 2003;52:1188-93.
106. Sugimoto H, Kaneko T, Hirota M, et al. Earlier hepatic vein transit-time measured by contrast ultrasonography reflects intrahepatic hemodynamic changes accompanying cirrhosis. J Hepatol 2002;37: 578-83.
107. Sato T, Yamazaki K, Toyota J, et al. Usefulness of electronic radial endoscopic color Doppler ultrasonography in esophageal varices: comparison with convex type. J Gastroenterol 2006;41:28-33.
108. Sato T, Yamazaki K, Toyota J, et al. Evaluation of arterial blood flow in esophageal varices via endoscopic color Doppler ultrasonography with a galactose-based contrast agent. J Gastroenterol 2005;40: 64-9.
109. Kaneko T, Teshigawara O, Sugimoto H, et al. Signal intensity of the liver parenchyma in microbubble contrast agent in the late liver phase reflects advanced fibrosis of the liver. Liver Int 2005;25: 288-93.
110. Harvey CJ, Blomley MJ, Eckersley RJ, et al. Pulse-inversion mode imaging of liver specific microbubbles: improved detection of subcentimetre metastases. Lancet 2000;355:807-8.